Decreased arthritis severity in cathepsin L-deficient mice is attributed to an impaired T helper cell compartment

Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice

(2010) Lisa Sevenich et al.   BIOCHIMIE

Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis

(2010) Urška Požgan et al.   BIOLOGICAL CHEMISTRY

Specialized roles for cysteine cathepsins in health and disease

(2010) Jochen Reiser et al.   JOURNAL OF CLINICAL INVESTIGATION

Diverse regulatory roles for lysosomal proteases in the immune response

(2009) Jeff D. Colbert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation evoked by collagen-induced arthritis in mice

(2009) Lena Svelander et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulatory T cells as therapeutic targets in rheumatoid arthritis

(2009) Jonathan H. Esensten et al.   Nature Reviews Rheumatology

Cleavage of Type II Collagen by Cathepsin K in Human Osteoarthritic Cartilage

(2008) Valeria M. Dejica et al.   AMERICAN JOURNAL OF PATHOLOGY

Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor–transgenic mice

(2008) Uta Schurigt et al.   ARTHRITIS AND RHEUMATISM