Article
Agriculture, Dairy & Animal Science
Mustafa Ozan Atasoy, Hakan Isidan, Turhan Turan
Summary: Calf diarrhea is a major problem in cattle farming, and this study investigated the infection frequencies of three pathogens in diarrhoeic bovines. The results showed that BRV and BCoV were the leading cause of gastroenteritis in young calves, while PBV was also associated with diarrhea. Sequence analysis revealed high genetic heterogeneity within PBV sequences, and co-infections of PBV with other enteric agents were detected for the first time.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2022)
Article
Multidisciplinary Sciences
Isabel Fuentes-Calvo, Cristina Cuesta, Sandra M. Sancho-Martinez, Omar A. Hidalgo-Thomas, Maria Paniagua-Sancho, Francisco J. Lopez-Hernandez, Carlos Martinez-Salgado
Summary: This study identified subclinical sequelae persisting after recovery from AKI in rats, including histological and functional alterations, as well as susceptibility to new AKI episodes. Additionally, potential diagnostic tools were found in the FST and urinary [TIMP-2]*[IGFBP7] product, to monitor the sequelae and kidney vulnerability after apparent recovery from AKI.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Geraldine Moloney, David W. Eyre, Micheal Mac Aogain, Maire C. McElroy, Alison Vaughan, Tim E. A. Peto, Derrick W. Crook, Thomas R. Rogers
Summary: Genomic analysis of a diverse collection of Clostridioides difficile ribotype 078 isolates from Ireland and 9 countries in Europe revealed complex regional and international dissemination patterns, not limited to humans, but also affecting pigs. These isolates are associated with C. difficile colonization and clinical illness in both humans and pigs.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Chatanun Eamudomkarn, Sirowan Ruantip, Jiraporn Sithithaworn, Anchalee Techasen, Kulthida Y. Kopoolrat, Chanika Worasith, Phattharaphon Wongphutorn, Jeffrey M. Bethony, Thewarach Laha, Paiboon Sithithaworn
Summary: Detection of anti-Strongyloides IgG in urine by ELISA showed comparable performance to conventional serum assays for diagnosing strongyloidiasis. Optimized urine ELISA protocols using different antigens yielded higher prevalence rates and showed potential as alternative diagnostic methods. The results supported the utility of urine specimens for the diagnosis of strongyloidiasis.
Article
Multidisciplinary Sciences
Julian Varghese, Sarah Sandmann, Kevin Ochs, Inga-Marie Schrempf, Christopher Froemmel, Martin Dugas, Hartmut H. Schmidt, Richard Vollenberg, Phil-Robin Tepasse
Summary: This study found that a majority of recovered COVID-19 patients experience persistent symptoms, with fatigue, dyspnea, and anosmia being the most common. Lymphopenia was a persistent laboratory finding, and patients with this condition were more likely to have persistent symptoms. Additionally, patients with persistent symptoms had significantly lower serum IgA levels, indicating a potential association between lymphopenia and persistence of COVID-19 symptoms.
SCIENTIFIC REPORTS
(2021)
Article
Obstetrics & Gynecology
Rita Zlatkin, Efraim Bilavsky, Joseph Pardo, Lina Salman, Ron Bardin, Eran Hadar, Anat Shmueli
Summary: This study evaluated the association between maternal CMV urinary excretion and congenital CMV infection, finding no association between the two in infants of women with primary CMV infection during pregnancy.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Virology
Mahdi Ouafi, Alexandre Regueme, Isabelle Alcaraz, Pierre Riviere, Helene Bazus, Arnaud Salmon-Rousseau, Bertrand Cappeliez, Noemie Cartier, Aurelie Guigon, Mouna Lazrek, Laurence Bocket, Emmanuel Faure, Olivier Robineau, Didier Hober, Enagnon Kazali Alidjinou
Summary: The ongoing outbreak of monkeypox virus is the largest in historically non-endemic countries, with atypical epidemiological and clinical presentations. This study found a significantly lower viral load in oropharyngeal samples compared to lesion samples, indicating that pharyngeal sampling does not provide additional information for the initial diagnosis in patients with typical lesions.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Multidisciplinary Sciences
Zhe Huang, Seung Goo Kang, Yunqiao Li, Jaroslav Zak, Namir Shaabani, Kaiyuan Deng, Jovan Shepherd, Raag Bhargava, John R. Teijaro, Changchun Xiao
Summary: Inhibition of IFN-I signaling in NK cells enhances the responses of CD4 and CD8 T cells, promotes humoral immune responses, and thereby facilitates the control of persistent virus infection.
Article
Multidisciplinary Sciences
Giulia Besutti, Paolo Giorgi Rossi, Marta Ottone, Lucia Spaggiari, Simone Canovi, Filippo Monelli, Efrem Bonelli, Tommaso Fasano, Nicola Sverzellati, Andrea Caruso, Nicola Facciolongo, Giulia Ghidoni, Anna Simonazzi, Mauro Iori, Andrea Nitrosi, Stefania Fugazzaro, Stefania Costi, Stefania Croci, Elisabetta Teopompi, Annalisa Gallina, Marco Massari, Giovanni Dolci, Fabio Sampaolesi, Pierpaolo Pattacini, Carlo Salvarani
Summary: Inflammatory burden during COVID-19 is associated with residual lung CT abnormalities in severe COVID-19 pneumonia survivors, suggesting that inflammation is linked to short- and medium-term lung damage in COVID-19 patients.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Ryota Itoh, Yusuke Kurihara, Michinobu Yoshimura, Kenji Hiromatsu
Summary: This study found that anticancer drugs, bortezomib and ixazomib, have strong inhibitory activity against Chlamydia, a parasitic intracellular bacterium that causes various infectious diseases. These drugs selectively eliminate Chlamydia-infected cells and show potential for treating chlamydial infections, including persistent infections.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Immunology
Richard A. Strugnell
Summary: IgA deficiency is a common immunodeficiency disease that affects a significant number of individuals. Recent studies have shown that the removal of secretory IgA can have subtle inflammatory consequences, suggesting a potential role for the excretory immune system in immune regulation.
FRONTIERS IN IMMUNOLOGY
(2022)
Letter
Biochemistry & Molecular Biology
Mai-Juan Ma, Shao-Fu Qiu, Xiao-Ming Cui, Ming Ni, Hong-Jie Liu, Run-Ze Ye, Lin Yao, Hong-Bo Liu, Wu-Chun Cao, Hong-Bin Song
Summary: Intra-host evolution of SARS-CoV-2 has been observed in symptomatic and immunocompromised cases, but not among asymptomatic cases. However, this study identified a group of asymptomatic cases with persistent infection and dynamic mutations of the virus. The dysregulation of immune responses, characterized by lower antibody levels and upregulation of CD4 regulatory T cells, may contribute to the persistent infection.
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2022)
Article
Virology
Zhiying Cui, Likun Zhou, Xingxing Hu, Shijie Zhao, Pengli Xu, Wen Li, Jing Chen, Yina Zhang, Pingan Xia
Summary: This study aimed to explore the pathogenesis mechanism of co-infection with PRRSV and PCV2. The results showed that co-infection had no effect on promoting PCV2 replication, but it could promote PRRSV replication. The immune regulatory molecules were down-regulated, while inflammatory factors and immune checkpoint molecules were up-regulated in the co-infection groups. These findings partially explain the enhanced pulmonary lesions caused by dual infection with PCV2 and PRRSV in PAMs.
Article
Surgery
Benjamin Del Tatto, Didier Le Roy, Martine Lambelet, Jean-Marc Corpataux, Nabil Chakfe, Stefano Giulieri, Florent Allagnat, Thierry Roger, Francois Saucy
Summary: Stapled porcine pericardium reduces the growth and adherence of bacteria and yeasts, making it a promising option for vascular grafting with lower infectivity. It outperforms native and sutured porcine pericardium in vitro.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Immunology
Mara Schwerdtfeger, Julia Dickow, Yasmin Schmitz, Sandra Francois, Zehra Karakoese, Anna Malyshkina, Torben Knuschke, Ulf Dittmer, Kathrin Sutter
Summary: Type I interferons (IFNs) play important roles in the immune response against viral infections, but they have opposing activities during acute and chronic retroviral infections. IFN alpha 11 has strong antiviral potential and can reactivate exhausted T cells during persistent infection, while IFN beta is involved in immune dysfunction in chronic infections.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Environmental Sciences
P. A. Barril, T. M. Fumian, V. E. Prez, P. I. Gil, L. C. Martinez, M. O. Giordano, G. Masachessi, M. B. Isa, L. J. Ferreyra, V. E. Re, M. Miagostovich, J. V. Pavan, S. V. Nates
ENVIRONMENTAL RESEARCH
(2015)
Article
Infectious Diseases
Gisela Masachessi, Balasubramanian Ganesh, Laura C. Martinez, Miguel O. Giordano, Patricia A. Barril, Maria B. Isa, Giorgio V. Pavan, Carlos A. Mateos, Silvia V. Nates
INFECTION GENETICS AND EVOLUTION
(2015)
Article
Environmental Sciences
V. E. Prez, P. I. Gil, C. F. Temprana, P. R. Cuadrado, L. C. Martinez, M. O. Giordano, G. Masachessi, M. B. Isa, V. E. Re, J. V. Pavan, S. V. Nates, P. A. Barril
SCIENCE OF THE TOTAL ENVIRONMENT
(2015)
Article
Public, Environmental & Occupational Health
M. B. Isa, J. V. Pavan, P. Sicilia Don, S. Grutadauria, L. C. Martinez, M. O. Giordano, G. Masachessi, P. A. Barril, S. V. Nates
EPIDEMIOLOGY AND INFECTION
(2014)
Article
Virology
Maribel G. Martinez Wassaf, Maria B. Pisano, Patricia A. Barril, Osvaldo C. Elbarcha, Marcelo A. Pinto, Jaqueline Mendes de Oliveira, Pablo DiGiusto, Silvia V. Nates, Viviana E. Re
JOURNAL OF CLINICAL VIROLOGY
(2014)
Article
Virology
Laura A. Yanez, Noelia S. Lucero, Patricia A. Barril, Maria del P. Diaz, Maria M. Tenaglia, Lorena I. Spinsanti, Silvia V. Nates, Maria B. Isa, Viviana E. Re
JOURNAL OF CLINICAL VIROLOGY
(2014)
Article
Multidisciplinary Sciences
C. Facundo Temprana, Marcelo H. Arguelles, Nicolas M. Gutierrez, Patricia A. Barril, Laura E. Esteban, Dalila Silvestre, Marcelo G. Mandile, Graciela Glikmann, Alejandro A. Castello
Article
Food Science & Technology
Patricia A. Barril, Silvina A. Soto, Maria V. Jaureguiberry, Gabriela Gottardi, Ianina Bascur, Gerardo A. Leotta, Juan M. Oteiza
LWT-FOOD SCIENCE AND TECHNOLOGY
(2019)
Article
Food Science & Technology
Juan M. Oteiza, Patricia A. Barril, Cesar E. Quintero, Marianela Savio, Romina Befani, Alicia Fernandez Cirelli, Natalia S. Echegaray, Carolina Murad, Ariel Buedo
Article
Environmental Sciences
Veronica Emilse Prez, Hugo Ramiro Poma, Georgina Gisela Giordano, Matias Victoria, Silvia Viviana Nates, Veronica Beatriz Rajal, Patricia Angelica Barril
JOURNAL OF WATER AND HEALTH
(2020)
Article
Environmental Sciences
G. Masachessi, V. E. Prez, J. F. Michelena, A. Lizasoain, L. J. Ferreyra, L. C. Martinez, M. O. Giordano, P. A. Barril, J. Pavan, M. B. Pisano, A. A. Farias, M. B. Isa, V. E. Re, R. Colina, S. Nates
Summary: An environmental survey conducted in San Roque Dam, Cordoba, Argentina revealed high detection frequencies of PBV, HAdV, and iEV, which were consistent over the years and not affected by seasonal patterns. The study suggests using these viruses to enhance the evaluation of microbiological quality in freshwater in Argentina.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Patricia Angelica Barril, Luis Alfredo Pianciola, Melina Mazzeo, Maria Julia Ousset, Maria Virginia Jaureguiberry, Mauricio Alessandrello, Gloria Sanchez, Juan Martin Oteiza
Summary: Wastewater-based epidemiology is a valuable tool for monitoring SARS-CoV-2 in communities and early detection of COVID-19 outbreaks. This study evaluated 11 different virus concentration techniques in wastewater and found that methods involving PEG precipitation and PAC flocculation showed high efficiency for virus recovery. Further testing showed that PAC flocculation had a lower limit of detection for SARS-CoV-2 compared to PEG precipitation.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Food Science & Technology
Juan M. Oteiza, Magdevis Y. R. Caturla, Leonardo Do Prado-Silva, Antonio A. Camara, Patricia A. Barril, Anderson S. Sant'Ana, Leda Giannuzzi, Noemi Zaritzky
Summary: This study evaluated the acid-adaptation and UV-C radiation resistance of both pathogenic and non-pathogenic strains of Escherichia coli in orange juice. The results showed that pre-exposure of the strains in orange juice for more than 2 hours increased their resistance to UV-C radiation. Additionally, the sensitivity to UV-C treatment varied among different strains. These findings provide valuable insights for the development of reliable UV-C radiation processes to inactivate pathogenic E. coli in orange juice.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Environmental Sciences
Juan Martin Oteiza, Veronica Emilse Prez, Dayana Pereyra, Maria Virginia Jaureguiberry, Gloria Sanchez, Anderson S. Sant'Ana, Patricia Angelica Barril
Summary: Berries have been implicated in the transmission of norovirus and hepatitis A virus outbreaks. This study investigated the virological quality of berries cultivated in Argentina and detected the presence of norovirus GII.6 in one out of 184 samples. The data collected provides important reference information for assessing the potential risk of soft fruits as vehicles for foodborne pathogenic viruses.
FOOD AND ENVIRONMENTAL VIROLOGY
(2022)
Article
Food Science & Technology
Patricia Angelica Barril, Juan Martin Oteiza, Javier Pardo, Gerardo Anibal Leotta, Marcelo Lisandro Signorini
Summary: This research analyzed the prevalence of human pathogens in vegetables, focusing on bacteria, parasites, and viruses. The study found relatively low occurrence rates of bacterial, parasitic, and viral hazards in vegetables, emphasizing the importance of proper sanitation methods for raw vegetables.
FOOD RESEARCH INTERNATIONAL
(2022)