Hydrophobic Determinants of  -Defensin Bactericidal Activity

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

(2012) Håkan S. Andersson et al.   AMINO ACIDS

Human  -Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide Nanonets

(2012) H. Chu et al.   SCIENCE

Criterion for Amino Acid Composition of Defensins and Antimicrobial Peptides Based on Geometry of Membrane Destabilization

(2011) Nathan W. Schmidt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II

(2010) Erik de Leeuw et al.   FEBS LETTERS

Trp-26 Imparts Functional Versatility to Human α-Defensin HNP1

(2010) Gang Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

Selective arginines are important for the antibacterial activity and host cell interaction of human α-defensin 5

(2009) Erik de Leeuw et al.   FEBS LETTERS

Electropositive Charge in  -Defensin Bactericidal Activity: Functional Effects of Lys-for-Arg Substitutions Vary with the Peptide Primary Structure

(2009) R. A. Llenado et al.   INFECTION AND IMMUNITY

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

Mechanisms of α-Defensin Bactericidal Action: Comparative Membrane Disruption by Cryptdin-4 and Its Disulfide-Null Analogue†

(2008) Chrystalleni Hadjicharalambous et al.   BIOCHEMISTRY

The Conserved Salt Bridge in Human α-Defensin 5 Is Required for Its Precursor Processing and Proteolytic Stability

(2008) Mohsen Rajabi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In VitroActivation of the Rhesus Macaque Myeloid α-Defensin Precursor proRMAD-4 by Neutrophil Serine Proteinases

(2008) Karishma Kamdar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY