Reversible Lipid Accumulation and Associated Division Arrest of Mycobacterium avium in Lipoprotein-Induced Foamy Macrophages May Resemble Key Events during Latency and Reactivation of Tuberculosis

Human Granuloma In Vitro Model, for TB Dormancy and Resuscitation

(2013) Nidhi Kapoor et al.   PLoS One

Identification of Residues Involved in Substrate Specificity and Cytotoxicity of Two Closely Related Cutinases from Mycobacterium tuberculosis

(2013) Luc Dedieu et al.   PLoS One

Mycobacterial lipolytic enzymes: A gold mine for tuberculosis research

(2012) L. Dedieu et al.   BIOCHIMIE

Mycobacterium tuberculosis-Driven Targeted Recalibration of Macrophage Lipid Homeostasis Promotes the Foamy Phenotype

(2012) Varshneya Singh et al.   Cell Host & Microbe

Infection of macrophages withMycobacterium tuberculosisinduces global modifications to phagosomal function

(2012) Maria Podinovskaia et al.   CELLULAR MICROBIOLOGY

Emerging Roles for Lipid Droplets in Immunity and Host-Pathogen Interactions

(2011) Hector Alex Saka et al.   Annual Review of Cell and Developmental Biology

Watching intracellular lipolysis in mycobacteria using time lapse fluorescence microscopy

(2011) Rabeb Dhouib et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) Protein Domains Target LipY Lipases of Pathogenic Mycobacteria to the Cell Surface via the ESX-5 Pathway

(2011) Maria H. Daleke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages

(2011) Jaiyanth Daniel et al.   PLoS Pathogens

Evidence for the cytotoxic effects of Mycobacterium tuberculosis phospholipase C towards macrophages

(2010) J.C. Bakala N'Goma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Modulation of lipid droplets by Mycobacterium leprae in Schwann cells: a putative mechanism for host lipid acquisition and bacterial survival in phagosomes

(2010) Katherine A. Mattos et al.   CELLULAR MICROBIOLOGY

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

(2010) Mi-Jeong Kim et al.   EMBO Molecular Medicine

Two cutinase-like proteins secreted by Mycobacterium tuberculosis show very different lipolytic activities reflecting their physiological function

(2010) Mathieu Schué et al.   FASEB JOURNAL

A Monoacylglycerol Lipase from Mycobacterium smegmatis Involved in Bacterial Cell Interaction

(2010) R. Dhouib et al.   JOURNAL OF BACTERIOLOGY

Mycobacterium requires an all-around closely apposing phagosome membrane to maintain the maturation block and this apposition is re-established when it rescues itself from phagolysosomes

(2009) Chantal de Chastellier et al.   CELLULAR MICROBIOLOGY

Cutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identification

(2009) Nicholas P. West et al.   FASEB JOURNAL

The many niches and strategies used by pathogenic mycobacteria for survival within host macrophages

(2009) Chantal de Chastellier   IMMUNOBIOLOGY

Triacylglycerol Utilization Is Required for Regrowth of In Vitro Hypoxic Nonreplicating Mycobacterium bovis Bacillus Calmette-Guerin

(2009) K. L. Low et al.   JOURNAL OF BACTERIOLOGY

Activity-Based Proteome Profiling of Potential Cellular Targets of Orlistat − An FDA-Approved Drug with Anti-Tumor Activities

(2009) Peng-Yu Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Therapeutic potential of lipase inhibitor orlistat in Alzheimer’s disease

(2009) Jing Du et al.   MEDICAL HYPOTHESES

Foamy macrophages and the progression of the human tuberculosis granuloma

(2009) David G Russell et al.   NATURE IMMUNOLOGY

A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen

(2009) Chirajyoti Deb et al.   PLoS One

Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids

(2009) Catherine Astarie-Dequeker et al.   PLoS Pathogens

Biogenesis of cytoplasmic lipid droplets: From the lipid ester globule in the membrane to the visible structure

(2008) Yuki Ohsaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The great divide: coordinating cell cycle events during bacterial growth and division

(2008) Daniel P Haeusser et al.   CURRENT OPINION IN MICROBIOLOGY

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous Sputum

(2008) Natalie J Garton et al.   PLOS MEDICINE

Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

(2008) Pascale Peyron et al.   PLoS Pathogens