Article
Ecology
Anilei Hoare, Hui Wang, Archana Meethil, Loreto Abusleme, Bo-Young Hong, Niki M. Moutsopoulos, Philip D. Marsh, George Hajishengallis, Patricia I. Diaz
Summary: Recent studies have shown that population size plays a crucial role in determining the growth, colonization, and virulence of the human oral pathogen Porphyromonas gingivalis, while cell-density-dependent diffusible cues exchanged between early and late colonizing species drive microbial successions, pathogen colonization, and disease development in a polymicrobial community.
Article
Medicine, General & Internal
Marushka L. Silveira, Colm D. Everard, Eva Sharma, Kristin Lauten, Apostolos A. Alexandridis, Kara Duffy, Ethel Taylor, Eric A. Tolliver, Carlos Blanco, Wilson M. Compton, Heather L. Kimmel, Timothy Iafolla, Andrew Hyland, Benjamin W. Chaffee
Summary: This study examined the associations between tobacco use and adverse oral health outcomes. The results showed that smoking was associated with gum disease, loose teeth, and tooth removal, while cigar smoking was associated with precancerous oral lesions. Additionally, hookah smoking was associated with gum disease, and ENDS use was associated with bleeding after brushing or flossing. These findings highlight the importance of longitudinal studies and tobacco cessation counseling in clinical practice.
Article
Multidisciplinary Sciences
Zhu Changkun, Ghose Bishwajit, Lu Ji, Shangfeng Tang
Summary: This study provides important insights into the current scenario of seeking cancer screening services among women in India. The findings suggest that older age, urban residence, higher education, employment, health insurance ownership, exposure to electronic media, higher household wealth, and better healthcare autonomy are associated with a higher uptake of cancer screening services. Additionally, the strength of these associations varies between urban and rural residents, indicating the need for region-specific intervention strategies.
Article
Microbiology
Leanne M. Cleaver, Rebecca V. Moazzez, Guy H. Carpenter
Summary: The study demonstrates that in a nutrient limited environment, proline has a beneficial effect on in vitro oral biofilms, promoting growth, reducing the number of dead bacteria, and maintaining the pH of the biofilms in a neutral range.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biology
Hidehiro Ishizawa, Masashi Kuroda, Daisuke Inoue, Michihiko Ike
Summary: Genome-wide transposon sequencing was used to identify genes involved in bacterial colonization and overall fitness on duckweed. The study found that the efficiency of initial colonization is mainly determined by the motility and cell surface structure of the bacteria, while overall fitness is associated with diverse metabolic and regulatory functions. Genes involved in the synthesis of lipopolysaccharides and type-IV pili showed different contributions to colonization and fitness, reflecting their metabolic cost and important roles in host association.
COMMUNICATIONS BIOLOGY
(2022)
Article
Biology
Catherine Weathered, Kelly Pennington, Patricio Escalante, Elsje Pienaar
Summary: MAC is a challenging pulmonary disease with increasing incidence and prevalence globally. The formation of biofilms by MAC aids in epithelial cell invasion. Understanding the impact of initial host immune levels, bacterial loads, and biofilm conditions on the course of infection is crucial for further exploration and development of prevention and treatment strategies targeting biofilm-macrophage interactions.
JOURNAL OF THEORETICAL BIOLOGY
(2022)
Review
Engineering, Environmental
Ana C. Afonso, Ines B. Gomes, Maria Jose Saavedra, Efstathios Giaouris, Lucia C. Simoes, Manuel Simoes
Summary: Bacterial coaggregation is believed to be a key step in the formation of sessile communities in aquatic systems, with bacteria capable of autoaggregation and coaggregation being found in various aquatic systems. The coaggregation mechanism plays an important role in the development and stability of multispecies biofilms, particularly with potential implications for controlling undesirable biofilms in wastewater treatment plants.
Article
Microbiology
Kassandra L. Dudek, Susanne Neuer
Summary: This study investigates the influence of plastic polymer type, incubation time, and geographic location on the microbial community of the plastisphere. The results show that bacterial community composition is primarily determined by the incubation time and geographic location, rather than plastic type. A core plastisphere consisting of 57 common amplicon sequence variants across all plastic types, incubation times, and locations was identified, suggesting potential synergistic interactions between taxa.
ENVIRONMENTAL MICROBIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Shima Afrasiabi, Nasim Chiniforush, Hamid Reza Barikani, Alireza Partoazar, Ramin Goudarzi
Summary: Pathogenic oral biofilms are recognized as a key factor in oral infectious diseases, and nanotechnology has brought about new methods to control bacterial biofilms and potentially reverse microbial dysbiosis for better oral health.
Review
Microbiology
Simon Alvarez, Camila Leiva-Sabadini, Christina M. A. P. Schuh, Sebastian Aguayo
Summary: This review explores the adhesion of oral bacteria to collagen surfaces and its impact on oral and systemic diseases, as well as its implications for collagen biomaterials and regenerative dentistry. The understanding of bacteria-collagen coupling is crucial for developing future therapeutic approaches.
CRITICAL REVIEWS IN MICROBIOLOGY
(2022)
Review
Substance Abuse
Tabassum Rahman, Parivash Eftekhari, Michelle Bovill, Amanda L. Baker, Gillian S. Gould
Summary: The research identified complex and overlapping barriers faced by Indigenous Australian pregnant and postpartum women at individual, family, community, societal, and system levels in quitting smoking. It also revealed the impact of factors such as racism and socioeconomic disadvantages during pregnancy on their smoking behavior.
NICOTINE & TOBACCO RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Samuel G. V. Charlton, Amber N. Bible, Eleonora Secchi, Jennifer L. Morrell-Falvey, Scott T. Retterer, Thomas P. Curtis, Jinju Chen, Saikat Jana
Summary: Biofilms are bacterial communities structured within an extracellular matrix, which plays a role in controlling their architecture and mechanical resistance. The research investigates the correlation between biofilm structure and viscoelastic response by comparing biofilms of Pantoea sp. (WT) and a mutant (& UDelta;UDP) with reduced exopolysaccharide production.
Article
Mathematics, Applied
Lucia M. Wagner, Sara M. Clifton
Summary: Since the introduction of electronic cigarettes to the U.S. market in 2007, vaping prevalence has increased significantly in adult and adolescent populations. Concerns have been raised by the U.S. government and health professionals about the attraction of e-cigarettes to young non-smokers. A dynamical systems model was developed to analyze the competition between traditional and electronic cigarettes, predicting changes in smoking prevalence and determining the conditions under which e-cigarettes may benefit or harm society's public health.
Article
Substance Abuse
Merideth A. Addicott, Alison H. Oliveto, Stacey B. Daughters
Summary: This study found that smokers showed larger differences in neural connectivity when experiencing affective distress compared to ex-smokers, indicating that smokers are more vulnerable to cognitive-affective distress.
DRUG AND ALCOHOL DEPENDENCE
(2023)
Article
Multidisciplinary Sciences
Mohit P. Dalwadi, Philip Pearce
Summary: Bacteria use quorum sensing to collectively respond to their environment, with their autoinducers affected by factors such as fluid flow. Understanding how genetic architectures in cells promote population-level phenotypes in varying flow conditions reveals that positive feedback in cells can lead to a robust collective response. By accounting for dynamic flow, positive feedback acts as a low-pass filter in oscillatory flow, allowing populations to respond to changes over slow timescales.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Editorial Material
Dentistry, Oral Surgery & Medicine
Purnima Kumar, Maria Geisinger, Hillary R. DeLong, Ruth D. Lipman, Marcelo W. B. Araujo
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2020)
Article
Dentistry, Oral Surgery & Medicine
P. S. Kumar, M. F. Monteiro, S. M. Dabdoub, G. L. Miranda, M. Z. Casati, F. V. Ribeiro, F. R. Cirano, S. P. Pimentel, R. C. V. Casarin
JOURNAL OF DENTAL RESEARCH
(2020)
Article
Multidisciplinary Sciences
Sukirth M. Ganesan, Shareef M. Dabdoub, Haikady N. Nagaraja, Michelle L. Scott, Surya Pamulapati, Micah L. Berman, Peter G. Shields, Mary Ellen Wewers, Purnima S. Kumar
Review
Dentistry, Oral Surgery & Medicine
Purnima S. Kumar, Kumar Subramanian
JOURNAL OF PERIODONTOLOGY
(2020)
Article
Dentistry, Oral Surgery & Medicine
Purnima S. Kumar, Maria L. Geisinger, Gustavo Avila-Ortiz
Summary: Infection control measures are crucial in preventing disease spread in dental settings, especially in procedures involving aerosol generation. Various infection control methods can be implemented to reduce the risk of infection transmission in dental environments.
JOURNAL OF PERIODONTOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
A. P. Meethil, S. Saraswat, P. P. Chaudhary, S. M. Dabdoub, P. S. Kumar
Summary: The study tracked the origins of microbiota in aerosols generated during dental procedures and found that most of the microbiota came from the dental irrigant, while saliva contributed minimally. The results indicate that dental treatment does not increase the risk of SARS-CoV-2 transmission in asymptomatic patients when infection control measures are used.
JOURNAL OF DENTAL RESEARCH
(2021)
Article
Microbiology
Khaled Altabtbaei, Pooja Maney, Sukirth M. Ganesan, Shareef M. Dabdoub, Haikady N. Nagaraja, Purnima S. Kumar
Summary: The study identified dysbiotic signatures in aggressive periodontitis, with LAP showing more phenotype-specific indicators. Genetic capabilities and metabolic pathways play important roles in all three forms of periodontitis.
Article
Dentistry, Oral Surgery & Medicine
Purnima S. Kumar
JOURNAL OF PERIODONTOLOGY
(2021)
Letter
Dentistry, Oral Surgery & Medicine
A. Meethil, S. Saraswat, P. P. Chaudhary, S. Dabdoub, P. Kumar
JOURNAL OF DENTAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Helvis E. S. Paz, Mabelle F. Monteiro, Camila S. Stolf, Khaled Altabtbaei, Marcio Z. Casati, Renato C. Casarin, Purnima S. Kumar
Summary: This study evaluated the taxonomic and predicted functional content of the subgingival microbiome of young patients with Grade C periodontitis under supportive periodontal therapy. The results showed that despite clinical improvements, the microbiome of these patients remained different from individuals without a history of disease.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Sukirth M. Ganesan, Shareef M. Dabdoub, Haikady N. Nagaraja, Angelo J. Mariotti, Christopher W. Ludden, Purnima S. Kumar
Summary: This study revealed that there is an active transcriptional activity of the peri-implant microbiome surrounding healthy implants. In disease conditions, an upregulation of microbial genes correlated with human genes, suggesting a potential role of commensals in maintaining epithelial integrity.
JOURNAL OF PERIODONTOLOGY
(2022)
Review
Dentistry, Oral Surgery & Medicine
Purnima S. Kumar
Article
Dentistry, Oral Surgery & Medicine
Aurelio Amorim Reis, Mabelle Freitas Monteiro, Gabriela Martin Bonilha, Luciana Saraiva, Cassia Araujo, Mauro Pedrine Santamaria, Marcio Zaffalon Casati, Purnima Kumar, Renato Correa Viana Casarin
Summary: The aim of this study was to evaluate microbial colonization in different dentition phases among individuals from 0 to 18 years old with a family history of periodontitis compared to descendants of periodontally healthy parents. The results showed that the parents' periodontal status significantly affected the microbiome composition of their offspring, and descendants with a family history of periodontitis exhibited different microbial diversity and a higher prevalence of periodontitis-associated species in the mixed and permanent dentition phases.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Khaled Sinjab, Shriya Sawant, Alice Ou, J. Christopher Fenno, Hom-Lay Wang, Purnima Kumar
Summary: This study aimed to investigate the impact of implant surface modifications on the peri-implant microbiome. The results showed that surface modifications did not significantly affect the microbiome of healthy implants, but had a significant impact on peri-implantitis (PI) implants. Furthermore, different surface modifications led to changes in the composition of bacterial species in healthy and PI implants.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Tamires Pereira Dutra, Mabelle Freitas Monteiro, Isabela Lima Franca-Grohmann, Renato Correa Viana Casarin, Marcio Zaffalon Casati, Karina Gonzalez Silverio Ruiz, Purnima S. Kumar, Enilson Antonio Sallum
Summary: This study compared individuals with a history of periodontitis to periodontally healthy subjects in terms of immunological and microbiological changes during experimental peri-implant mucositis and gingivitis. The results showed that different microbial shifts contribute to the onset and progression of inflammatory responses around teeth and implants, while the history of periodontal disease plays a role in modulating the immune response.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)