Attaching and Effacing Bacterial Effector NleC Suppresses Epithelial Inflammatory Responses by Inhibiting NF-κB and p38 Mitogen-Activated Protein Kinase Activation

A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation

(2011) Jaclyn S. Pearson et al.   MOLECULAR MICROBIOLOGY

IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7

(2011) Fengyi Wan et al.   NATURE IMMUNOLOGY

The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling

(2010) Stephanie R. Shames et al.   CELLULAR MICROBIOLOGY

Metalloprotease type III effectors that specifically cleave JNK and NF-κB

(2010) Kobi Baruch et al.   EMBO JOURNAL

Interleukin-11 Reduces TLR4-Induced Colitis in TLR2-Deficient Mice and Restores Intestinal STAT3 Signaling

(2010) Deanna L. Gibson et al.   GASTROENTEROLOGY

Novel Changes in NF-κB Activity during Progression and Regression Phases of Hyperplasia

(2010) Parthasarathy Chandrakesan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome-independent Degradation of Canonical NFκB Complex Components by the NleC Protein of PathogenicEscherichia coli

(2010) Sabrina Mühlen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gut inflammation provides a respiratory electron acceptor for Salmonella

(2010) Sebastian E. Winter et al.   NATURE

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Type III Secretion Effector NleE Inhibits NF-κB Activation

(2010) Chen Nadler et al.   PLoS Pathogens

The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-κB p65

(2010) Hayley J. Newton et al.   PLoS Pathogens

NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelA

(2010) Hilo Yen et al.   PLoS Pathogens

Lipopolysaccharide activates innate immune responses in murine intestinal myofibroblasts through multiple signaling pathways

(2009) Kristen L. W. Walton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

p38 Mitogen-activated protein kinase signalling regulates vascular inflammation and epithelial barrier dysfunction in an experimental model of radiation-induced colitis

(2009) A. Mihaescu et al.   BRITISH JOURNAL OF SURGERY

The effector repertoire of enteropathogenic E. coli: ganging up on the host cell

(2009) Paul Dean et al.   CURRENT OPINION IN MICROBIOLOGY

A Comprehensive Proteomic Analysis of the Type III Secretome ofCitrobacter rodentium

(2009) Wanyin Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms of Escherichia coli pathogenicity

(2009) Matthew A. Croxen et al.   NATURE REVIEWS MICROBIOLOGY

Bacterial Effector Binding to Ribosomal Protein S3 Subverts NF-κB Function

(2009) Xiaofei Gao et al.   PLoS Pathogens

Flagellin-Dependent and -Independent Inflammatory Responses following Infection by Enteropathogenic Escherichia coli and Citrobacter rodentium

(2008) M. A. Khan et al.   INFECTION AND IMMUNITY

Complete Genome Sequence and Comparative Genome Analysis of Enteropathogenic Escherichia coli O127:H6 Strain E2348/69

(2008) A. Iguchi et al.   JOURNAL OF BACTERIOLOGY

Direct Visualization of Horizontal Gene Transfer

(2008) A. Babic et al.   SCIENCE

MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis

(2007) D. L. Gibson et al.   CELLULAR MICROBIOLOGY