期刊
INDIAN PEDIATRICS
卷 50, 期 2, 页码 237-242出版社
SPRINGER INDIA
DOI: 10.1007/s13312-013-0041-0
关键词
Thalidomide; Juvenile idiopathic arthritis
类别
Systemic onset juvenile idiopathic arthritis (SOJIA) is the most common autoimmune auto inflammatory disease in childhood. A sizeable number of these patients run a recalcitrant disease course, resistant to the conventional line of management, ultimately resulting in permanent disability from joint destruction, local growth deformities or iatrogenic side effects. The new biological agents although very effective, are beyond the affordability of most in our country. Thalidomide, a cheaper option has been shown to be very effective in the disease control of patients with SOJIA. We report three Indian children with a chronic refractory course of SOJIA, all of whom had failed conventional line of treatment but improved with thalidomide.
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