Article
Biochemistry & Molecular Biology
Qing Yi-Jun Zhou, Xin Liao, Hao-Ming Kuang, Jia-Yu Li, Shui-Han Zhang
Summary: This study systematically identified the metabolites in extracts from the roots, leaves, twigs, and fruits of the Morus alba tree, and evaluated their hypoglycemic activity. The extracts from the roots and twigs showed significant hypoglycemic activity, and a high-level component called morusin was found to decrease blood glucose levels. This research provides a basis for further development of Morus alba extracts as anti-diabetic drugs.
Article
Nutrition & Dietetics
Tae Sik Sung, Seung-Bum Ryoo, Chang-Hyun Lee, Seon-Min Choi, Joo-Won Nam, Hyun-Bok Kim, Ji Young Lee, Jung-Dae Lim, Kyu Joo Park, Hyun-Tai Lee
Summary: The fruit of Morus alba L. (MAF) has been used as a food worldwide and in traditional medicine in East Asia for thousands of years. This study found that MAF has prokinetic activity and can enhance gastrointestinal motor function in mice and human intestines. It increased both myogenic and neurogenic contractions, resulting in accelerated intestinal transit rate (ITR). These findings suggest that MAF has potential as a new prokinetic agent.
Article
Plant Sciences
Sureeporn Suriyaprom, Thida Kaewkod, Itthayakorn Promputtha, Mickael Desvaux, Yingmanee Tragoolpua
Summary: White mulberries from Chiang Mai and Mae Hong Son provinces in Thailand exhibit high antioxidant and antibacterial activities, especially in aqueous extracts. They can effectively inhibit the growth of certain pathogenic bacteria causing gastrointestinal tract infections and prevent their adhesion to intestinal epithelial cells.
Article
Plant Sciences
Meng Zhu, Zhao-Jie Wang, Ying-Jie He, Yan Qin, Ying Zhou, Zi-Heng Qi, Zhong-Shun Zhou, Yan-Yan Zhu, Dan-Ni Jin, Shan-Shan Chen, Xiao-Dong Luo
Summary: Compounds in the root bark of Morus alba have shown promising antibacterial activity against MRSA, potentially serving as a new antibacterial medicine or a potential efflux pump inhibitor for MRSA infection.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Plant Sciences
Yahui Xuan, Bi Ma, Dong Li, Yu Tian, Qiwei Zeng, Ningjia He
Summary: This study analyzed the genome of wild mulberry species M. notabilis, revealing the chromosomal synteny and restructuring process between wild and cultivated mulberry. The activity of the centromere was found to be crucial for stable chromosome inheritance. Long terminal repeat retrotransposons were identified as the major driver of mulberry genome divergence and evolution after divergence.
HORTICULTURE RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Lu Yang, Jiuyang Zhao, Shaoli Fan, Jinfa Liao, Yicun Chen, Yangdong Wang
Summary: Mulberry leaves collected after frost have superior medicinal properties. This study conducted metabolic profiling analyses on two types of mulberry leaves harvested at different times and identified over 100 compounds. The results showed that frost had different effects on the accumulation of metabolites in Morus nigra L. and Morus alba L., and picking time also influenced the levels of DNJ alkaloids and flavonoids in mulberry leaves.
Article
Green & Sustainable Science & Technology
Ahmet Can, Ahmet Kazankaya, Erdal Orman, Muttalip Gundogdu, Sezai Ercisli, Ravish Choudhary, Rohini Karunakaran
Summary: This study analyzed 55 wild-grown mulberry landraces in the Van Lake basin, belonging to Morus alba, Morus rubra, and Morus nigra species, to determine their fruit characteristics. The research found that chlorogenic acid and rutin were the predominant compounds in all mulberry landraces. Malic acid was identified as the dominant organic acid among genotypes. These findings suggest that these mulberry landraces could be valuable for breeding purposes and may have potential health benefits due to their rich bioactive compounds.
Article
Agronomy
Yuyang Cong, Yang Liu, Yurong Tang, Jiale Ma, Xingyu Wang, Shuai Shen, Hong Zhang
Summary: The collaborative action of microwave and vacuum can cause increases in temperature and the gasification of water, leading to cell swelling, changes in fiber structures, and the formation of microstructures. This study investigated the dehydration characteristics of mulberries using microwave-vacuum drying technology. The optimized Two-term model successfully predicted the dehydration process of mulberries under various drying variables. The optimal drying variables were determined based on the crispness of the dried mulberries, and the diffusion coefficient and activation energy for drying were also determined.
Article
Biochemistry & Molecular Biology
Seung-Hwa Baek, Sungbo Hwang, Tamina Park, Yoon-Ju Kwon, Myounglae Cho, Daeui Park
Summary: The study revealed that kuwanon A is a compound with selective COX-2 inhibitory activity, which interacts strongly with key positions at the COX active site, potentially explaining its high selectivity and efficacy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Horticulture
Surapon Saensouk, Rattanavalee Senavongse, Chanakran Papayrata, Theeraphan Chumroenphat
Summary: This study investigated the color, phytochemical compounds, and antioxidant activity in mulberry fruit during seven ripening stages. The results show that different ripening stages of mulberry fruits contain varying levels of nutrients and antioxidants, with increasing ripeness leading to enhanced antioxidant activity.
Article
Medicine, Research & Experimental
Anna Gryn-Rynko, Iga Holynska-Iwan, Michal Adam Janiak, Dorota Olszewska-Slonina, Ryszard Amarowicz, Radomir Graczyk
Summary: Morus alba L., a herbal plant with therapeutic properties, has been found to affect ion channels in rabbit colon epithelium, leading to changes in electrical potential. This study provides valuable insights into the pharmacological effects of white mulberry leaves.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Plant Sciences
Li Liu, Nan Chao, Keermula Yidilisi, Xiaoru Kang, Xu Cao
Summary: This study conducted a comprehensive identification and functional analysis of MYBs in Morus, providing functional annotation for R2R3-MYBs and serving as an informative reference for further research on the functionality of MYBs in Morus.
Article
Multidisciplinary Sciences
Agnieszka Bilska
Summary: The study found that the addition of mulberry leaf extract can delay fat oxidation in meat products, enhance their antioxidant activity and inhibitory enzyme activity. After adding mulberry leaf extract in simulated liver pates, the products maintained high sensory quality and unchanged microbiological quality during storage.
Article
Plant Sciences
Michael Ackah, Yisu Shi, Mengmeng Wu, Lei Wang, Peng Guo, Liangliang Guo, Xin Jin, Shaocong Li, Qiaonan Zhang, Changyu Qiu, Qiang Lin, Weiguo Zhao
Summary: The study examined the impact of drought stress on mulberry Yu-711 metabolic balance using a global metabolomic analysis approach. Results revealed significant alterations in various metabolic components, with a more differentiated metabolite response under drought stress conditions compared to the control. The levels of total lipids, galactolipids, and phospholipids were significantly altered, while other classes of metabolites also showed dynamic trends in response to drought stress.
Article
Pharmacology & Pharmacy
Sheng-li Pei, Fang Kan, Chun-jiang Yue
Summary: The study showed that Morus alba extract has significant antihypertensive effects in renovascular hypertensive rats, possibly through inhibiting endothelin-converting enzyme and exerting antioxidant activity. Additionally, it significantly improved renal function in the rats.
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
(2021)