Review
Microbiology
Cecile Philippe, Jeffrey K. Cornuault, Alessandra G. de Melo, Rachel Morin-Pelchat, Alice P. Jolicoeur, Sylvain Moineau
Summary: Over the past few decades, there has been a growing interest in lactic acid bacteria (LAB) due to their industrial use, health benefits, and ecological importance. However, phage infection poses a significant risk to LAB production and use. This review discusses the defense systems employed by LAB against phage infections and the strategies used by phages to overcome these defenses. It also explores the impact of phage-host interactions on their evolution and highlights the potential of novel defense systems discovered in other bacteria for phage research in LAB.
FEMS MICROBIOLOGY REVIEWS
(2023)
Article
Chemistry, Multidisciplinary
Giulia Tuci, Andrea Rossin, Xiong Zhang, Lai Truong-Phuoc, Enrico Berretti, Yuefeng Liu, Cuong Pham-Huu, Sajjad Ali, Faheem Jan, Lorenzo Poggini, Giuliano Giambastiani
Summary: Hydrogen peroxide (H2O2) electrosynthesis via 2e(-) Oxygen Reduction Reaction (ORR) is an environmentally friendly and cost-effective alternative to the current anthraquinone-based technology. Various lightweight element hetero-doped carbon nanostructures, particularly those containing O-functionalities, show promise as cheap metal-free electrocatalysts for H2O2 synthesis. The covalent exohedral functionalization of the outer surface of extra-pure multi-walled carbon nanotubes (MWCNTs) with discrete O-functional groups provides new insights into the structure/reactivity relationship of O-containing carbon-based catalysts for ORR, clarifying the role of hydroxyl/phenol groups as key functionalities.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Review
Oncology
Liliana Montella, Margaret Ottaviano, Rocco Morra, Erica Pietroluongo, Pietro De Placido, Marianna Tortora, Chiara Sorrentino, Gaetano Facchini, Sabino De Placido, Mario Giuliano, Giovannella Palmieri
Summary: Thymic epithelial tumors are rare and often associated with paraneoplastic syndromes. Treatment options include surgical resection, platinum-refractory therapies, and somatostatin analogs, but their exact role in thymic tumors remains unclear.
Article
Engineering, Environmental
You Zhang, Wenhong Fan, Xiaomin Li, Wen-Xiong Wang, Shu Liu
Summary: In this study, nanobubble technology and hydrogen water were combined for the first time to remove reactive oxygen species caused by environmental stress. Hydrogen nanobubbles showed remarkable capability in removing H2O2 and O(2)(center dot- ), and increasing the activity and expression of antioxidant enzymes.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Otorhinolaryngology
Emily Z. Yan, Benjamin M. Wahle, Erik R. Nakken, Smrithi Chidambaram, Kayla Getz, Wade L. Thorstad, Jose P. Zevallos, Angela L. Mazul
Summary: Clinical outcomes in patients with oral cavity squamous cell carcinoma (OCSCC) who have never smoked or drunk alcohol are similar to those who have had tobacco and alcohol exposure, when adjusted for independent biological features.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Article
Biochemistry & Molecular Biology
Leanne E. Mocniak, Zachary T. Bitzer, Neil Trushin, John P. Richie
Summary: Tobacco smoke free radicals, which depend on the intrinsic nitrate levels in tobacco, are closely associated with adverse health effects. The levels of gas phase radicals are highly correlated with nitrate levels in different tobacco types and brands. Nitrate addition to tobacco leaves increases the production of gas phase radicals and NNK in smoke. Tobacco nitrate plays a key role in the production of gas phase radicals and has implications for health regulation.
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Review
Surgery
Ali R. Ahmadi, Liron S. Duraku, Mark J. W. van der Oest, Caroline A. Hundepool, Ruud W. Selles, J. Michiel Zuidam
Summary: This study compared the outcomes of PRC and FCA in the treatment of type two and type three SLAC and SNAC-induced degenerative arthritis. The results showed no significant difference between PRC and FCA in any of the outcome measures. However, due to the high risk of bias in the studies, further validation is needed for the results.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2022)
Article
Environmental Sciences
Periklis Vardakas, Ioannis A. Kartsonakis, Ioannis D. Kyriazis, Panagiotis Kainourgios, Aikaterini Flora A. Trompeta, Constantinos A. Charitidis, Demetrios Kouretas
Summary: The purpose of this study was to evaluate the antioxidant properties of MWCNTs and their hybrid nanocomposites. The results showed that most of the tested MWCNTs exhibited strong antioxidant activities, with CNTs@Fe3O4 material showing the strongest radical scavenging capacity, CNTs-Ref material exhibiting high electron donating capacity, and CNTs@SiC material having potent ability to inhibit the formation of peroxyl radicals, thus preventing oxidative DNA damage.
ENVIRONMENTAL RESEARCH
(2023)
Article
Food Science & Technology
Juan David Figueroa, Noreima Barroso-Torres, Marcela Morales, Barbara Herrera, Mario Aranda, Eva Dorta, Camilo Lopez-Alarcon
Summary: The ORAC assay does not differentiate between peptides based on their chemical structures and the contribution of oxidation products. Peptides showed similar ORAC values, but the bond dissociation energy (BDE) varied.
Article
Engineering, Environmental
Shi-Ming Jia, De-Qi Wang, Li-Yan Liu, Zi-Feng Zhang, Wan-Li Ma
Summary: The study comprehensively investigated the distribution of environmental persistent free radicals (EPFRs) in different size particles and evaluated the inhalation exposure risk. The results showed that the concentration of EPFRs was higher during heating season compared to non-heating season. The contribution of EPFRs in PM>10 to the total concentration of EPFRs cannot be neglected, particularly during non-heating season. The study also indicated a higher inhalation exposure risk for 3-4-year-old children.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Multidisciplinary Sciences
Thales Henrique B. De Oliveira, Norma B. De Gusmao, Leonor A. O. Da Silva, Luana C. B. B. Coelho
Summary: Free radicals are harmful to human health and antioxidants can stabilize these molecules. Actinobacteria, a less explored natural source of antioxidants, has been found to possess important capacity in producing these compounds.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2021)
Article
Biochemistry & Molecular Biology
Thi Chinh Ngo, Dinh Hieu Truong, Thi Thuy Nga Nguyen, Duong Tuan Quang, Duy Quang Dao
Summary: The primary and secondary antioxidant activities of pyridoxal were investigated using density functional theory. The results showed that pyridoxal exhibited efficient radical scavenging ability towards HO· and NO2· radicals in water.
Article
Oncology
Xuqi Sun, Lingling Li, Li Xu, Zhongguo Zhou, Jinbin Chen, Juncheng Wang, Yaojun Zhang, Dandan Hu, Minshan Chen
Summary: The study found that prior cancer history did not compromise the survival of hepatocellular carcinoma (HCC) patients, regardless of tumor stage or cancer interval period. The exclusion criteria for HCC clinical trials may need to be reconsidered.
Article
Oncology
Seung-hwan Jeong, Jang Hee Han, Chang Wook Jeong, Hyeon Hoe Kim, Cheol Kwak, Hyeong Dong Yuk, Ja Hyeon Ku
Summary: This study retrospectively examined prospective patients enrolled in the registry of Seoul National University to determine the clinical significance of CA 19-9 in UTUC, finding that high serum CA 19-9 levels are associated with poor prognosis in UTUC, particularly in patients with high T and N stages.
FRONTIERS IN ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jessie Kang, Sharon E. Clarke, Mohammed Abdolell, Ravi Ramjeesingh, Jennifer Payne, Andreu F. Costa
Summary: The study evaluated the proportion of missed/misinterpreted imaging examinations in patients with PDAC, finding that delays in imaging were associated with longer diagnostic intervals but did not impact overall survival due to the poor prognosis of the disease.
EUROPEAN RADIOLOGY
(2021)
