Article
Medicine, Research & Experimental
Hsiao-Chi Lai, Chang-Shen Lin, Ching-Shuang Wu, Cheng-Che E. Lan
Summary: The study showed that low irradiance UVB induced significantly more aberrant epidermal proliferation via enhanced ROS and pAKT signaling compared to high irradiance UVB at equivalent fluence. Reducing UVB-induced AKT phosphorylation presents a novel strategy to improve the protective capacity of the currently available sunscreens.
Article
Immunology
Han Liu, Xiaopu Guo, Tangwei Yi, Yihan Zhu, Xinyi Ren, Renxian Guo, Yi Dai, Shaohui Liang
Summary: The tree frog Hyla annectans in the southwestern plateau area of China may possess novel peptides with anti-inflammatory and antioxidant properties, which can protect the skin from UV-induced damage by modulating stress signaling pathways.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Rengin Ozgur, Baris Uzilday, Tolga Yalcinkaya, Turgut Yigit Akyol, Hasan Yildirim, Ismail Turkan
Summary: The study found that compared to Arabidopsis thaliana, Arabis alpina showed better antioxidant response and lipid peroxide detoxification under UV-B stress, providing greater protection to PSII.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2021)
Review
Cell Biology
Tetsuya Ishimoto, Hisashi Mori
Summary: This mini review provides an overview of advancements in controlling intracellular actin polymerization using optical approaches and discusses future challenges.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Chemistry, Medicinal
Yuqian Wang, Dan Han, Yingjian Huang, Yilin Dai, Yan Wang, Meng Liu, Ning Wang, Tingyi Yin, Wenqian Du, Ke He, Yan Zheng
Summary: Punicalagin-enriched pomegranate extract can alleviate inflammation and lesions in psoriasis, inhibit cell proliferation and cytokine expression, and improve the quality of life for patients.
PHYTOTHERAPY RESEARCH
(2023)
Article
Tropical Medicine
Cheol Park, Da Hye Kwon, Hyesook Lee, Su Hyun Hong, Gi-Young Kim, Hee-Jae Cha, Do-Hyung Kim, Suhkmann Kim, Heui-Soo Kim, Hye-Jin Hwang, Yung Hyun Choi
Summary: The study showed that ethanol extracts of Chondracanthus tenellus can enhance immunomodulatory properties by activating the TLR4/NF-kappa B signaling pathway, leading to increased production of immunomodulatory mediators and cytokines. This suggests that EECT has the potential to enhance immune activity.
ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE
(2021)
Article
Chemistry, Physical
Haiyin Zhan, Qixing Zhou, Mingmei Li, Ruiren Zhou, Yueshuang Mao, Pengfei Wang
Summary: By designing B-x-C3N4 material, the efficiency of photocatalytic activity is greatly improved due to the enhanced O-2 adsorption energy and electron transfer efficiency. This leads to a significant enhancement in photocatalytic degradation.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2022)
Article
Dermatology
Pranjal Gohad, John McCoy, Carlos Wambier, Maja Kovacevic, Mirna Situm, Andrija Stanimirovic, Andy Goren
Summary: Studies have found that CBD has a protective effect on keratinocytes and melanocytes in sunscreen products, showing a dose-dependent relationship. This protective effect is likely due to the reduction in reactive oxygen species by CBD, even though it does not absorb in the UVB spectra.
JOURNAL OF COSMETIC DERMATOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Wisurumuni Arachchilage Hasitha Maduranga Karunarathne, Ilandarage Menu Neelaka Molagoda, Kyoung Tae Lee, Yung Hyun Choi, Sang-Mi Yu, Chang-Hee Kang, Gi-Young Kim
Summary: The study found that AHs extracted from the flower petals of H. syriacus L. have anti-aging, antioxidant, and anti-melanogenic properties, protecting the skin from UVB-induced photodamage. AHs prevented apoptosis, ER stress, and mtROS production induced by UVB irradiation, effectively preventing skin cell damage.
Article
Cell Biology
Chenjun Guo, Xiaona Ning, Jie Zhang, Chen Zhang, Jue Wang, Liping Su, Jing Han, Nan Ma
Summary: Exposure to UVB radiation leads to the formation of cataracts by inducing excessive reactive oxygen species (ROS) and apoptosis in human lens epithelial cells (HLECs). Sodium-dependent Vitamin C transports-2 (SVCT2) is downregulated in UVB-treated HLECs, leading to increased ROS accumulation and apoptosis. The NF-κB/SVCT2/AsA regulatory pathway may provide therapeutic potential in UVB-induced cataract.
Article
Biochemistry & Molecular Biology
Sin Ri Kim, Ji Won Park, Byung-Hoon Lee, Kyung Min Lim, Tong-Shin Chang
Summary: Ultraviolet B (UVB) irradiation induces the production of reactive oxygen species (ROS), leading to damage in exposed skin cells. Mitochondria and NADPH oxidase are two major sources of ROS in UVB-irradiated keratinocytes. Peroxiredoxin V (PrxV) is a cysteine-dependent peroxidase enzyme found in mitochondria and cytosol, which effectively removes H2O2. We investigated the role of PrxV in protecting epidermal keratinocytes against UVB-induced ROS damage.
Review
Immunology
Esen Yonca Bassoy, Michael Walch, Denis Martinvalet
Summary: The immune system protects the host by distinguishing self from non-self and relying on two lines of defense - the fast-acting innate immune system followed by the slower but potent adaptive immune system. T lymphocytes and B lymphocytes are essential for eliminating pathogens and establishing immunological memory.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Naihui Guo, Shengjia Tang, Jiayu Wang, Shikai Hu, Shaoqing Tang, Xiangjin Wei, Gaoneng Shao, Guiai Jiao, Zhonghua Sheng, Peisong Hu
Summary: This study investigated the mechanism of hormone and reactive oxygen species (ROS) crosstalk in regulating rice dormancy using Zhonghua11 (ZH11) and Introgression line (IL) varieties. Transcriptome and proteome analysis identified differentially expressed genes (DEGs) and proteins (DEPs) between IL and ZH11. Hormone content detection revealed significant differences in abscisic acid (ABA) and jasmonic acid (JA) levels between IL and ZH11. ROS content measurement showed variations in hydrogen peroxide (H2O2) and superoxide anion (O-2(.-)) levels between IL and ZH11. These findings suggest that hormones and ROS play a role in rice dormancy regulation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Tropical Medicine
Da Hye Kwon, Cheol Park, Hyesook Lee, Su Hyun Hong, Gi-Young Kim, Hee-Jae Cha, Suhkmann Kim, Heui-Soo Kim, Hye-Jin Hwang, Yung Hyun Choi
Summary: The ethanol extract of Chondracanthus tenellus showed potential anti-inflammatory and antioxidant effects by downregulating NF-kappa B, MAPKs, and PI3K/Akt signaling pathways in LPS-stimulated RAW 264.7 macrophages.
ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE
(2021)
Review
Agronomy
Rupal Singh Tomar, Sunita Kataria, Anjana Jajoo
Summary: This article explores the recent research on signaling and mechanisms for salt tolerance in plants, focusing on the role of the salt overly sensitive system (SOS) and related antiporters proteins and mitogen-activated protein kinase cascades under salt stress. It also highlights the differential expression of various antioxidative enzymes in C3, C4 and CAM plants.
JOURNAL OF AGRONOMY AND CROP SCIENCE
(2021)