Article
Public, Environmental & Occupational Health
Sarah M. Alexander, Alfred Agaba, Jeffrey I. Campbell, Nuriat Nambogo, Carol S. Camlin, Mallory Johnson, Grant Dorsey, Kristian R. Olson, David R. Bangsberg, Ryan W. Carroll, Data Santorino, Paul J. Krezanoski
Summary: In Uganda, households generally find the use of SmartNet for monitoring bednet usage acceptable and similar to standard LLINs. The large size, soft fabric, and perceived efficacy of SmartNet contribute to its perceived usefulness and ease of use. However, some concerns such as difficulties in washing nets and dislike of blinking lights on the device were expressed as opportunity costs by households.
Article
Public, Environmental & Occupational Health
Adama Traore, Laura Donovan, Benoit Sawadogo, Charlotte Ward, Helen Smith, Christian Rassi, Helen Counihan, Johanna Johansson, Sol Richardson, Justin Ragnessi Savadogo, Kevin Baker
Summary: This study assessed the acceptability and feasibility of extending seasonal malaria chemoprevention (SMC) from four to five cycles in Mangodara health district in Burkina Faso. The results showed that the extension was perceived as acceptable by caregivers, community distributors, and stakeholders, despite concerns over conflicts with farming activities. The data from end-of-cycle surveys indicated no difference in coverage between five SMC cycles and four cycles in comparison districts.
Article
Health Care Sciences & Services
Jody L. Lin, Bernd Huber, Ofra Amir, Sebastian Gehrmann, Kimberly S. Ramirez, Kimberly M. Ochoa, Steven M. Asch, Krzysztof Z. Gajos, Barbara J. Grosz, Lee M. Sanders
Summary: This study aimed to assess the feasibility and acceptability of GoalKeeper (GK), an internet-based system for eliciting and monitoring family-centered goals for children with medical complexity (CMC). The results showed that family-centered technologies like GK are feasible and acceptable for the care of CMC, but integrating them into electronic health records remains a key challenge.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Pediatrics
Rebecca E. Lee, Michael Todd, Hyunsung Oh, SeungYong Han, Michelle Santana, Jaquelyn Aguilar-Troncoso, Meg Bruening, Joanna L. Kramer, Tomas Leon, Vel Murugan, Hector Valdez, Michelle Villegas-Gold
Summary: A study examined the acceptability and feasibility of using a COVID-19 saliva test for young children and their caregivers in preschools. The results showed that saliva testing is an acceptable strategy for 4- and 5-year-olds, but alternate testing strategies may be needed for younger children.
Article
Infectious Diseases
Nnenna Ogbulafor, Perpetua Uhomoibhi, Emmanuel Shekarau, Jamilu Nikau, Chukwu Okoronkwo, Nadia M. L. Fanou, Ibrahima Marietou Mbaye, Jean-Louis Ndiaye, Andre-Marie Tchouatieu, Abena Poku-Awuku, Corinne Merle, Susana Scott, Paul Milligan, Aminu Ali, Hauwa'u Evelyn Yusuf, Stephen Oguche, Tukur Dahiru
Summary: Despite the large-scale expansion of SMC, this study in Nigeria demonstrates that the attitude towards SMC is positive, with people perceiving it as a key preventive measure against malaria. The findings reinforce the importance of continuing to deliver SMC door-to-door.
Article
Health Care Sciences & Services
Omolola Oyinkan Adeshina, Solomon Nyame, James Milner, Ai Milojevic, Kwaku Poku Asante
Summary: This study examined the factors that would influence or hinder the implementation of the malaria vaccine in Ghana. The main driving forces were the disease burden, vaccine efficacy, stakeholder involvement, and feasibility evidence generated by researchers. The logistics of vaccine delivery were identified as the most influential barrier.
HEALTH POLICY AND PLANNING
(2023)
Article
Multidisciplinary Sciences
Emily Hayward, Kiera Solaiman, Penny Bee, Amy Barr, Hannah J. Edwards, Jennifer Lomas, Lucy Tindall, Alexander J. Scott, Katie Biggs, Barry Wright
Summary: A study conducted in the UK compared the effectiveness of One-Session Treatment and Cognitive Behavioural Therapy for children and young people with specific phobias. The qualitative evaluation showed that One-Session Treatment was deemed acceptable and identified barriers and facilitators for its implementation. Further research comparing children and young people's experiences of receiving Cognitive Behavioural Therapy and One-Session Treatment would be valuable.
Article
Multidisciplinary Sciences
Emily Hayward, Kiera Solaiman, Penny Bee, Amy Barr, Hannah Edwards, Jennifer Lomas, Lucy Tindall, Alexander J. Scott, Katie Biggs, Barry Wright
Summary: A trial conducted in the UK examined the non-inferiority of One-Session Treatment compared to Cognitive Behavioural Therapy for children with specific phobias. The trial found One-Session Treatment to be an acceptable intervention, but identified barriers for its implementation.
Article
Public, Environmental & Occupational Health
Rita Nakalega, Nelson Mukiza, Robert Menge, Samuel Kizito, Juliet Allen Babirye, Cynthia Ndikuno Kuteesa, Denis Mawanda, Emmie Mulumba, Josephine Nabukeera, Joseph Ggita, Lydia Nakanjako, Carolyne Akello, Brenda Gati Mirembe, Zubair Lukyamuzi, Catherine Nakaye, Hajira Kataike, Joel Maena, Juliane Etima, Hadijah Kalule Nabunya, Florence Biira, Christine Nagawa, Renee Heffron, Connie Celum, Monica Gandhi, Andrew Mujugira
Summary: Peer delivery of HIV self-tests (HIVST) and oral pre-exposure prophylaxis (PrEP) was found to be feasible and acceptable among young women with suboptimal PrEP adherence in Uganda. This intervention improved linkage to HIV care and medication adherence, addressing the high HIV infection rates among adolescent girls and young women.
Article
Anesthesiology
Melanie Hamilton, Stephanie Mathieson, Danijela Gnjidic, Jesse Jansen, Kristie Weir, Christina A. Shaheed, Fiona Blyth, Chung-Wei C. Lin
Summary: This study investigated the barriers and facilitators to deprescribing opioid analgesics in patients with chronic noncancer pain. The study found that doctors face many difficulties including considering patient factors and varying prescribing practices. Patient motivation and doctor-patient rapport are central factors to facilitate deprescribing and doctors consider a multidisciplinary network of clinicians to be the most important resource.
Article
Psychology, Multidisciplinary
Signe Hjelen Stige, Tonje Barca, Kristina Osland Lavik, Christian Moltu
Summary: Mental health problems often start early in life. This study conducted interviews with 12 young people who entered mental health care reluctantly before the age of 18. Despite sharing the same starting point, their journeys through mental health care varied significantly, resulting in three distinct trajectories.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Health Care Sciences & Services
Ronald Anguzu, Laura D. Cassidy, Kirsten M. M. Beyer, Harriet M. Babikako, Rebekah J. Walker, Julia Dickson-Gomez
Summary: This study explored the facilitators and barriers to intimate partner violence screening during pregnancy by healthcare providers in Uganda. It found that limited resources, lack of training, and provider unawareness were barriers to routine screening. Availability of protocols and knowledge of screening tools acted as facilitators.
BMC HEALTH SERVICES RESEARCH
(2022)
Article
Multidisciplinary Sciences
Laura K. Beres, Ismail Mbabali, Aggrey Anok, Charles Katabalwa, Jeremiah Mulamba, Alvin G. Thomas, Eva Bugos, Mary K. Grabowski, Gertrude Nakigozi, Larry Chang
Summary: Valid and reliable behavioral data, along with contextually meaningful interventions, are necessary for improving health outcomes. Ecological Momentary Assessment and Intervention (EMAI) collects real-time data and delivers interventions as behaviors occur, potentially making it more accurate and reliable than retrospective methods. This study assesses the acceptability and feasibility of EMAI in sub-Saharan Africa, using mobile technologies for remote data collection and intervention. The results show that EMAI was acceptable and feasible, with good response rates. However, additional strategies to improve compliance should be investigated.
Article
Urology & Nephrology
Sijrike F. van der Mei, Manna A. Alma, Angelique E. de Rijk, Sandra Brouwer, Ron T. Gansevoort, Casper F. M. Franssen, Stephan J. L. Bakker, Marc H. Hemmelder, Ralf Westerhuis, Marjolijn van Buren, Annemieke Visser
Summary: Through a qualitative study, this research aimed to describe the barriers to and facilitators of sustained employment experienced by Dutch patients with CKD. The results showed a wide range of barriers and facilitators in health-related, personal, and environmental factors, highlighting the importance of personalized nephrology and occupational health care for promoting sustained employment for patients with CKD.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2021)
Article
Infectious Diseases
Monnaphat Jongdeepaisal, Mom Ean, Chhoeun Heng, Thoek Buntau, Rupam Tripura, James J. Callery, Thomas J. Peto, Franca Conradis-Jansen, Lorenz von Seidlein, Panarasri Khonputsa, Kulchada Pongsoipetch, Ung Soviet, Siv Sovannaroth, Christopher Pell, Richard J. Maude
Summary: The study found that prophylaxis with artemether-lumefantrine for forest goers was acceptable under trial conditions. Three factors were key: community awareness and perception of the effectiveness of prophylaxis, trust in the provider, and malaria as a local health concern. The findings emphasize how uptake and adherence to prophylaxis are influenced by the perceived balance between benefits and burden of anti-malarials, modulated by the seasonality of forest visits and its influence on malaria risk.
Article
Infectious Diseases
Ann-Sophie Stratil, Lieven Vernaeve, Sergio Lopes, Yves Bourny, Kylie Mannion, Prudence Hamade, Arantxa Roca-Feltrer, James K. Tibenderana, Siv Sovannaroth, Mark Debackere
Summary: Tailored proactive and reactive case detection strategies have successfully reached remote populations in Cambodia to support the elimination of Plasmodium falciparum malaria. Mobile malaria workers conducted effective testing and case detection in forested border areas, playing a key role in achieving the goal of malaria elimination.
Article
Infectious Diseases
Hannah M. Edwards, Rubaiyath Sarwar, Parvez Mahmud, Shekarau Emmanuel, Kolawole Maxwell, James K. Tibenderana
Summary: The private sector in Nigeria has a significant role in malaria treatment. The Affordable Medicines Facility-Malaria and the private sector co-payment mechanism (PSCM) have improved access to and affordability of artemisinin-based combination therapy (QA-ACT). Results show that the PSCM has increased the availability and market reach of subsidized and non-subsidized ACT medicines, leading to increased market competition and reduced costs. However, concerns remain regarding the market share of non-QA brands and oral artemisinin monotherapies.
Article
Infectious Diseases
Alyssa J. Young, Will Eaton, Matt Worges, Honelgn Hiruy, Kolawole Maxwell, Bala Mohammed Audu, Madeleine Marasciulo, Charles Nelson, James Tibenderana, Tarekegn A. Abeku
Summary: This work provides a practical mechanism for prioritizing geographic areas for insecticide-treated net (ITN) distribution campaigns. It offers a tool that can be applied in various country contexts, providing expedited outputs and utilizing systematically collected malaria indicators to inform prioritization.
Article
Infectious Diseases
Anthony Nuwa, Janet Oola, Sam Okot Obonyo, Mitra Feldman, Shirah Karungi, Edmound Kertho, David Salandini Odong, Isaac Kimera, Godfrey Magumba, Geofrey Beinomugisha, Alexandra Chitty, James Tibenderana, Jimmy Opigo, Francis Abwaimo
Summary: This study compares the impact of district-led and national-led malaria surveillance and response systems on the malaria burden in Nwoya district, Uganda. The findings indicate that district-led systems can effectively reduce malaria cases and positivity rates, while also being sustainable and efficient.
Correction
Infectious Diseases
Chris Ebong, Asadu Sserwanga, Jane Frances Namuganga, James Kapisi, Arthur Mpimbaza, Samuel Gonahasa, Victor Asua, Sam Gudoi, Ruth Kigozi, James Tibenderana, John Bosco Bwanika, Agaba Bosco, Denis Rubahika, Daniel Kyabayinze, Jimmy Opigo, Damian Rutazana, Gloria Sebikaari, Kassahun Belay, Mame Niang, Eric S. Halsey, Leah F. Moriarty, Naomi W. Lucchi, Samaly S. Svigel Souza, Sam L. Nsobya, Moses R. Kamya, Adoke Yeka
Article
Infectious Diseases
Jane Achan, Asadu Serwanga, Humphrey Wanzira, Tonny Kyagulanyi, Anthony Nuwa, Godfrey Magumba, Stephen Kusasira, Isaac Sewanyana, Kevin Tetteh, Chris Drakeley, Fredrick Nakwagala, Helen Aanyu, Jimmy Opigo, Prudence Hamade, Madeleine Marasciulo, Byarugaba Baterana, James K. Tibenderana
Summary: This study revealed a prevalence of 12% of P falciparum infection in COVID-19 patients in Uganda, with higher rates in younger and older age groups. Co-infection with P falciparum was associated with more frequent confusion and vomiting. Patients with low previous exposure to P falciparum had increased frequency of severe or critical COVID-19, especially when no comorbidities were present.
Letter
Biochemistry & Molecular Biology
Branwen Nia Owen, Munir Winkel, Craig Bonnington, Anthony Nuwa, Jane Achan, Jimmy Opigo, James K. Tibenderana, Emilie Pothin
Article
Infectious Diseases
Hannah M. Edwards, Rubaiyath Sarwar, Parvez Mahmud, Shekarau Emmanuel, Kolawole Maxwell, James K. Tibenderana
Summary: Correct diagnosis of fever is essential in the private healthcare sector in Nigeria before prescribing drugs. However, the availability of malaria rapid diagnostic tests (RDTs) is low, which may be attributed to low demand, supply-side issues, and high prices. Increasing household knowledge of RDTs and subsidizing RDTs can address these issues.
Article
Infectious Diseases
Adeola Y. Olukosi, Olusola Ajibaye, Omowunmi Omoniwa, Olusola Oresanya, Aina O. Oluwagbemiga, Chinazo Ujuju, Michael Ekholuenetale, Kolawole Maxwell, Colin J. Sutherland, James K. Tibenderana, Khalid B. Beshir
Summary: A rapid surveillance study was conducted in Ebonyi and Osun states in Nigeria to assess the suitability of sulfadoxine/pyrimethamine (SP) as perennial malaria chemoprevention (PMC). The study revealed that both states are suitable for SP-PMC implementation, and it has been implemented in Osun since 2022. Continuous monitoring of the 540E mutation is necessary to ensure the effectiveness of SP chemoprevention in Nigeria.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2023)
Article
Infectious Diseases
Manuela Runge, Anne Stahlfeld, Monique Ambrose, Kok Ben Toh, Semiu Rahman, Omowunmi F. Omoniwa, Caitlin A. Bever, Olusola Oresanya, Perpetua Uhomoibhi, Beatriz Galatas, James K. Tibenderana, Jaline Gerardin
Summary: Perennial malaria chemoprevention (PMC) can significantly reduce clinical and severe malaria cases in areas with high malaria burden and perennial transmission. However, a better understanding of the malaria risk profile by age and feasible coverage by age is needed for selecting an appropriate PMC schedule.
Article
Infectious Diseases
Anthony Nuwa, Kevin Baker, Craig Bonnington, Musa Odongo, Tonny Kyagulanyi, John Baptist Bwanika, Sol Richardson, Jane Nabakooza, Jane Achan, Richard Kajubi, David Salandini Odong, Maureen Nakirunda, Godfrey Magumba, Geofrey Beinomugisha, Madeleine Marasciulo-Rice, Hilda Abio, Christian Rassi, Damian Rutazaana, Denis Rubahika, James Tibenderana, Jimmy Opigo
Summary: A study in the Karamoja sub-region of Uganda assessed the protective effectiveness of monthly administration of SP + AQ for malaria prevention in children aged 3-59 months. The study found that the intervention significantly reduced the incidence of malaria, with a protective effectiveness of 92%.
Article
Parasitology
Leo Braack, Shobiechah A. Wulandhari, Emmanuel Chanda, Florence Fouque, Corinne S. Merle, Udoka Nwangwu, Raman Velayudhan, Marietjie Venter, A. Gildas Yahouedo, Jo Lines, Poe Poe Aung, Kallista Chan, Tarakegn A. Abeku, James Tibenderana, Sian E. Clarke
Summary: This meeting report summarizes the key findings and discussions of a 3-hour virtual workshop organized by the RAFT research consortium on 21 September 2022. The workshop aimed to identify priorities for advancing arbovirus research, network, and capacity strengthening in Africa, where mosquito-borne arboviral diseases are increasing in distribution and prevalence. The report highlights the current status of arboviruses in Africa, the importance of networking, and the main priorities identified by breakout groups.
PARASITES & VECTORS
(2023)
Meeting Abstract
Public, Environmental & Occupational Health
Anthony Nuwa, Geofrey Beinomugisha, Geofrey Magumba, David Salandini, Flavia Mpanga, Francis Abwaimo, Musa Odongo, Maureen Amutuhaire, Robinah Lukwago, Fred Kagwire, Shirah Karungi, James Tibenderana
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2021)
Meeting Abstract
Public, Environmental & Occupational Health
Anthony Nuwa, Jimmy Opigo, Maureen Nakirunda, Kevin Baker, David Salandini, Tonny Kyagulanyi, Craig Bonnington, Christian Rassi, Madeleine Marasciulo-Rice, Godfrey Magumba, Musa Odongo, Jane Achan, Sol Richardson, Jane Nabakooza, Denis Rubahika, James Tibenderana
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2021)
Meeting Abstract
Public, Environmental & Occupational Health
Branwen Nia Owen, Munir Winkel, Laura Skrip, Craig Bonnington, Jane Achan, Jimmy Opigo, James Tibenderana, Emilie Pothin
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2021)