The CD8 T-cell road to immunotherapy of toxoplasmosis

Cutting Edge: T-bet and IL-27R Are Critical for In Vivo IFN-  Production by CD8 T Cells during Infection

(2014) K. D. Mayer et al.   JOURNAL OF IMMUNOLOGY

IL-12 Signaling Drives CD8 + T Cell IFN-γ Production and Differentiation of KLRG1 + Effector Subpopulations during Toxoplasma gondii Infection

(2014) Douglas C. Wilson et al.   JOURNAL OF IMMUNOLOGY

Removal of Toxoplasma gondii Cysts from the Brain by Perforin-Mediated Activity of CD8+ T Cells

(2010) Yasuhiro Suzuki et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of CD8+ T cell responses to infection with parasitic protozoa

(2010) Kimberly A. Jordan et al.   EXPERIMENTAL PARASITOLOGY

Generation of effector CD8+ T cells and their conversion to memory T cells

(2010) Weiguo Cui et al.   IMMUNOLOGICAL REVIEWS

Polyfunctional CD4+ and CD8+ T Cell Responses to Tuberculosis Antigens in HIV-1-Infected Patients before and after Anti-Retroviral Treatment

(2010) J. S. Sutherland et al.   JOURNAL OF IMMUNOLOGY

IL-21 Deficiency Influences CD8 T Cell Quality and Recall Responses following an Acute Viral Infection

(2010) J. S. Yi et al.   JOURNAL OF IMMUNOLOGY

Virulence of Toxoplasma gondii Is Associated with Distinct Dendritic Cell Responses and Reduced Numbers of Activated CD8+ T Cells

(2010) E. D. Tait et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cell Inhibition Is Connected to Exhaustion of CD8+ T Cell Polyfunctionality during Chronic Hepatitis C Virus Infection

(2010) I. G. Rodrigue-Gervais et al.   JOURNAL OF IMMUNOLOGY

Vaccines against Toxoplasma gondii: challenges and opportunities

(2010) Erik Jongert et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Absence of Both IL-7 and IL-15 Severely Impairs the Development of CD8+ T Cell Response against Toxoplasma gondii

(2010) Rajarshi Bhadra et al.   PLoS One

Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques

(2010) Y. Sui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-10 directly suppresses CD4 but not CD8 T cell effector and memory responses following acute viral infection

(2010) D. G. Brooks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transnuclear Mice with Predefined T Cell Receptor Specificities Against Toxoplasma gondii Obtained via SCNT

(2010) O. Kirak et al.   SCIENCE

Towards an immunosense vaccine to prevent toxoplasmosis: Protective Toxoplasma gondii epitopes restricted by HLA-A*0201

(2010) Hua Cong et al.   VACCINE

Differential Regulation of Effector- and Central-Memory Responses to Toxoplasma gondii Infection by IL-12 Revealed by Tracking of Tgd057-Specific CD8+ T Cells

(2010) Douglas C. Wilson et al.   PLoS Pathogens

Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

(2009) J. R. Almeida et al.   BLOOD

Current status of toxoplasmosis vaccine development

(2009) Józef Kur et al.   Expert Review of Vaccines

Behavior of Parasite-Specific Effector CD8+ T Cells in the Brain and Visualization of a Kinesis-Associated System of Reticular Fibers

(2009) Emma H. Wilson et al.   IMMUNITY

Transcriptional Repressor Blimp-1 Promotes CD8+ T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties

(2009) Rachel L. Rutishauser et al.   IMMUNITY

Mechanisms of costimulation

(2009) Arlene H. Sharpe   IMMUNOLOGICAL REVIEWS

Kinetics and Phenotype of Vaccine-Induced CD8+ T-Cell Responses to Toxoplasma gondii

(2009) K. A. Jordan et al.   INFECTION AND IMMUNITY

Long-Term Immunity to Lethal Acute or Chronic Type II Toxoplasma gondii Infection Is Effectively Induced in Genetically Susceptible C57BL/6 Mice by Immunization with an Attenuated Type I Vaccine Strain

(2009) J. P. Gigley et al.   INFECTION AND IMMUNITY

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

(2009) Fernando Cruz-Guilloty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dynamic Imaging of T Cell-Parasite Interactions in the Brains of Mice Chronically Infected with Toxoplasma gondii

(2009) Marie Schaeffer et al.   JOURNAL OF IMMUNOLOGY

IL-21 Is Required to Control Chronic Viral Infection

(2009) H. Elsaesser et al.   SCIENCE

Spatiotemporal Regulation of T Cell Costimulation by TCR-CD28 Microclusters and Protein Kinase C θ Translocation

(2008) Tadashi Yokosuka et al.   IMMUNITY

Parasite Stage–Specific Recognition of EndogenousToxoplasma gondii–Derived CD8+T Cell Epitopes

(2008) Eva‐Maria Frickel et al.   JOURNAL OF INFECTIOUS DISEASES

Emergence of Polyfunctional CD8+ T Cells after Prolonged Suppression of Human Immunodeficiency Virus Replication by Antiretroviral Therapy

(2008) M. Rehr et al.   JOURNAL OF VIROLOGY

Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum

(2008) Nicolas Blanchard et al.   NATURE IMMUNOLOGY

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY