标题
Potential targets for pancreatic cancer immunotherapeutics
作者
关键词
-
出版物
Immunotherapy
Volume 3, Issue 4, Pages 517-537
出版商
Future Medicine Ltd
发表日期
2011-04-04
DOI
10.2217/imt.11.10
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer
- (2014) M. C. B. Tan et al. JOURNAL OF IMMUNOLOGY
- Adoptive T-cell Immunotherapy of Cancer Using Chimeric Antigen Receptor-Grafted T Cells
- (2010) David Marc Davies et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Current strategies to target p53 in cancer
- (2010) Fang Chen et al. BIOCHEMICAL PHARMACOLOGY
- Single, double and triple alanine to glycine replacements in the AxAxAxA motif of alkaliphilic Bacillus pseudofirmus OF4 c-subunits affect c-ring stability, change both monomer and c-ring mobility in SDS-PAGE and lead to deficits in ATP synthesis
- (2010) Jun Liu et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Cancer Statistics, 2010
- (2010) A. Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Development of a live and highly attenuated Listeria monocytogenes-based vaccine for the treatment of Her2/neu-overexpressing cancers in human
- (2010) V Shahabi et al. CANCER GENE THERAPY
- Anti-tumor immunotherapy despite immunity to adenovirus using a novel adenoviral vector Ad5 [E1-, E2b-]-CEA
- (2010) Elizabeth S. Gabitzsch et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Generation of a tumor vaccine candidate based on conjugation of a MUC1 peptide to polyionic papillomavirus virus-like particles
- (2010) Sharmila Pejawar-Gaddy et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Anti-HER2 vaccines: new prospects for breast cancer therapy
- (2010) Maha Zohra Ladjemi et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Vaccine Prevention of Cancer: Can Endogenous Antigens Be Targeted?
- (2010) L. M. Weiner et al. Cancer Prevention Research
- Increased Immunogenicity of Tumor-Associated Antigen, Mucin 1, Engineered to Express -Gal Epitopes: A Novel Approach to Immunotherapy in Pancreatic Cancer
- (2010) T. Deguchi et al. CANCER RESEARCH
- Tumor vaccines in 2010: Need for integration
- (2010) David Koos et al. CELLULAR IMMUNOLOGY
- Transforming growth factor-β and the hallmarks of cancer
- (2010) Maozhen Tian et al. CELLULAR SIGNALLING
- Cancer Vaccine by Fusions of Dendritic and Cancer Cells
- (2010) Shigeo Koido et al. Clinical & Developmental Immunology
- Recent Advances in Anti-Survivin Treatments for Cancer
- (2010) R. Kanwar et al. CURRENT MEDICINAL CHEMISTRY
- MUC1 immunotherapy
- (2010) Richard E Beatson et al. Immunotherapy
- A novel high-affinity human monoclonal antibody to mesothelin
- (2010) Mitchell Ho et al. INTERNATIONAL JOURNAL OF CANCER
- Selective Expansion of Chimeric Antigen Receptor-targeted T-cells with Potent Effector Function using Interleukin-4
- (2010) Scott Wilkie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Putting the brakes on BTLA in T cell–mediated cancer immunotherapy
- (2010) Chrystal M. Paulos et al. JOURNAL OF CLINICAL INVESTIGATION
- BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination
- (2010) Laurent Derré et al. JOURNAL OF CLINICAL INVESTIGATION
- An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer
- (2010) Michael A. Morse et al. JOURNAL OF CLINICAL INVESTIGATION
- Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates
- (2010) Julie R. Brahmer et al. JOURNAL OF CLINICAL ONCOLOGY
- Single-Chain HLA-A2 MHC Trimers That Incorporate an Immundominant Peptide Elicit Protective T Cell Immunity against Lethal West Nile Virus Infection
- (2010) S. Kim et al. JOURNAL OF IMMUNOLOGY
- Heterologous Prime/Boost Immunization With p53-based Vaccines Combined With Toll-like Receptor Stimulation Enhances Tumor Regression
- (2010) Hidenobu Ishizaki et al. JOURNAL OF IMMUNOTHERAPY
- Current Experience With CTLA4-blocking Monoclonal Antibodies for the Treatment of Solid Tumors
- (2010) Sanjiv S. Agarwala et al. JOURNAL OF IMMUNOTHERAPY
- Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma
- (2010) Richard E. Royal et al. JOURNAL OF IMMUNOTHERAPY
- Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy
- (2010) Pravin Mishra et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The patterns and dynamics of genomic instability in metastatic pancreatic cancer
- (2010) Peter J. Campbell et al. NATURE
- Genome remodelling in a basal-like breast cancer metastasis and xenograft
- (2010) Li Ding et al. NATURE
- Distant metastasis occurs late during the genetic evolution of pancreatic cancer
- (2010) Shinichi Yachida et al. NATURE
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
- (2010) Philip W. Kantoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chemoradiation in Pancreatic Adenocarcinoma: A Literature Review
- (2010) R. Roy et al. ONCOLOGIST
- Reactivity of a humanized antibody (hPankoMab) towards a tumor-related MUC1 epitope (TA-MUC1) with various human carcinomas
- (2010) Xiao-Na Fan et al. PATHOLOGY RESEARCH AND PRACTICE
- Listeria and Salmonella bacterial vectors of tumor-associated antigens for cancer immunotherapy
- (2010) Yvonne Paterson et al. SEMINARS IN IMMUNOLOGY
- Immune Checkpoint Proteins: A New Therapeutic Paradigm for Cancer—Preclinical Background: CTLA-4 and PD-1 Blockade
- (2010) Jeffrey Weber SEMINARS IN ONCOLOGY
- Engineering superior DNA vaccines: MHC class I single chain trimers bypass antigen processing and enhance the immune response to low affinity antigens
- (2010) Lijin Li et al. VACCINE
- Combined cetuximab and trastuzumab are superior to gemcitabine in the treatment of human pancreatic carcinoma xenografts
- (2009) C. Larbouret et al. ANNALS OF ONCOLOGY
- The Human Cancer Antigen Mesothelin Is More Efficiently Presented to the Mouse Immune System when Targeted to the DEC-205/CD205 Receptor on Dendritic Cells
- (2009) Bei Wang et al. Annals of the New York Academy of Sciences
- Induction of protective and therapeutic anti-pancreatic cancer immunity using a reconstructed MUC1 DNA vaccine
- (2009) Yefei Rong et al. BMC CANCER
- Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis
- (2009) S Q Ashraf et al. BRITISH JOURNAL OF CANCER
- Concurrent vaccination with two distinct vaccine platforms targeting the same antigen generates phenotypically and functionally distinct T-cell populations
- (2009) Amanda L. Boehm et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Phase I clinical trial using peptide vaccine for human vascular endothelial growth factor receptor 2 in combination with gemcitabine for patients with advanced pancreatic cancer
- (2009) Motoki Miyazawa et al. CANCER SCIENCE
- Survivin: A new target for anti-cancer therapy
- (2009) Bríd M. Ryan et al. CANCER TREATMENT REVIEWS
- Protective anti-tumour immune responses by murine dendritic cells pulsed with recombinant Tat-carcinoembryonic antigen derived fromEscherichia coli
- (2009) M.-Y. Bae et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Phase I Trial of Continuous Infusion Anti-Mesothelin Recombinant Immunotoxin SS1P
- (2009) R. J. Kreitman et al. CLINICAL CANCER RESEARCH
- Genetically Targeted T Cells Eradicate Established Breast Cancer in Syngeneic Mice
- (2009) H. Wang et al. CLINICAL CANCER RESEARCH
- Circulating Mesothelin Protein and Cellular Antimesothelin Immunity in Patients with Pancreatic Cancer
- (2009) F. Mc. Johnston et al. CLINICAL CANCER RESEARCH
- A Novel Human Her-2/neu Chimeric Molecule Expressed by Listeria monocytogenes Can Elicit Potent HLA-A2 Restricted CD8-positive T cell Responses and Impact the Growth and Spread of Her-2/neu-positive Breast Tumors
- (2009) M. M. Seavey et al. CLINICAL CANCER RESEARCH
- Novel agents for the treatment of adenocarcinoma of the pancreas
- (2009) R Pamela Mackenzie et al. Expert Review of Anticancer Therapy
- Anti-MUC1 Nanobody Can Redirect T-Body Cytotoxic Effector Function
- (2009) Seyed Hamid Aghaee Bakhtiari et al. HYBRIDOMA
- An Anti-Vascular Endothelial Growth Factor Receptor 2/Fetal Liver Kinase-1 Listeria monocytogenes Anti-Angiogenesis Cancer Vaccine for the Treatment of Primary and Metastatic Her-2/neu+ Breast Tumors in a Mouse Model
- (2009) M. M. Seavey et al. JOURNAL OF IMMUNOLOGY
- A Herceptin-Based Chimeric Antigen Receptor with Modified Signaling Domains Leads to Enhanced Survival of Transduced T Lymphocytes and Antitumor Activity
- (2009) Y. Zhao et al. JOURNAL OF IMMUNOLOGY
- Antitumor Efficacy of Trastuzumab in Nude Mice Orthotopically Xenografted With Human Pancreatic Tumor Cells Expressing Low Levels of HER-2/neu
- (2009) Graziella Pratesi et al. JOURNAL OF IMMUNOTHERAPY
- Allogeneic Melanoma Vaccine Expressing αGal Epitopes Induces Antitumor Immunity to Autologous Antigens in Mice Without Signs of Toxicity
- (2009) Gabriela R. Rossi et al. JOURNAL OF IMMUNOTHERAPY
- Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs
- (2009) Mark M Aloysius et al. Journal of Translational Medicine
- A novel human monoclonal antibody that binds with high affinity to mesothelin-expressing cells and kills them by antibody-dependent cell-mediated cytotoxicity
- (2009) Y. Feng et al. MOLECULAR CANCER THERAPEUTICS
- The cancer vaccine roller coaster
- (2009) Bruce Goldman et al. NATURE BIOTECHNOLOGY
- Immune infiltration in human tumors: a prognostic factor that should not be ignored
- (2009) F Pagès et al. ONCOGENE
- High expression of N-acetylglucosaminyltransferase V in mucinous tumors of the ovary
- (2009) Yamamoto ONCOLOGY REPORTS
- Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
- (2009) C. Carpenito et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Late administration of plasmid DNA by intradermal electroporation efficiently boosts DNA-primed T and B cell responses to carcinoembryonic antigen
- (2009) Andreas Bråve et al. VACCINE
- Two novel HLA-A*0201 T-cell epitopes in avian H5N1 viral nucleoprotein induced specific immune responses in HHD mice
- (2009) Ying-Kit Cheung et al. VETERINARY RESEARCH
- The αGal HyperAcute®Technology: Enhancing Immunogenicity of Antiviral Vaccines by Exploiting the Natural αGal-Mediated Zoonotic Blockade
- (2009) R. B. Mandell et al. Zoonoses and Public Health
- Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen
- (2008) P J Conaghan et al. BRITISH JOURNAL OF CANCER
- Anti-Mesothelin Antibodies and Circulating Mesothelin Relate to the Clinical State in Ovarian Cancer Patients
- (2008) I. Hellstrom et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Pilot study of mutant ras peptide-based vaccine as an adjuvant treatment in pancreatic and colorectal cancers
- (2008) Antoun Toubaji et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy
- (2008) C. Marcela Diaz-Montero et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Immunosurveillance of pancreatic adenocarcinoma: Insights from genetically engineered mouse models of cancer
- (2008) Carolyn E. Clark et al. CANCER LETTERS
- Equilibrium between Host and Cancer Caused by Effector T Cells Killing Tumor Stroma
- (2008) B. Zhang et al. CANCER RESEARCH
- Epitope Landscape in Breast and Colorectal Cancer
- (2008) N. H. Segal et al. CANCER RESEARCH
- The Immunogenicity of the hTERT540-548 Peptide in Cancer
- (2008) L. Wenandy et al. CLINICAL CANCER RESEARCH
- Vaccination with a Recombinant Saccharomyces cerevisiae Expressing a Tumor Antigen Breaks Immune Tolerance and Elicits Therapeutic Antitumor Responses
- (2008) E. K. Wansley et al. CLINICAL CANCER RESEARCH
- Second-Generation Anti-Carcinoembryonic Antigen Designer T Cells Resist Activation-Induced Cell Death, Proliferate on Tumor Contact, Secrete Cytokines, and Exhibit Superior Antitumor Activity In vivo: A Preclinical Evaluation
- (2008) P. C.R. Emtage et al. CLINICAL CANCER RESEARCH
- Targeted Therapies to Improve Tumor Immunotherapy
- (2008) J. Begley et al. CLINICAL CANCER RESEARCH
- Phase I Safety and Pharmacokinetic Study of CT-011, a Humanized Antibody Interacting with PD-1, in Patients with Advanced Hematologic Malignancies
- (2008) R. Berger et al. CLINICAL CANCER RESEARCH
- DNA vaccination and gene therapy: optimization and delivery for cancer therapy
- (2008) Angela M Bodles-Brakhop et al. Expert Review of Vaccines
- Strategies used for MUC1 immunotherapy: human clinical studies
- (2008) Choon-Kit Tang et al. Expert Review of Vaccines
- Host responses to alphavirus infection
- (2008) Kate D. Ryman et al. IMMUNOLOGICAL REVIEWS
- Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape
- (2008) Jessica B. Katz et al. IMMUNOLOGICAL REVIEWS
- A Binding Domain on Mesothelin for CA125/MUC16
- (2008) Osamu Kaneko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anti–Cytotoxic T-Lymphocyte Antigen-4 Antibody: The First in an Emerging Class of Immunomodulatory Antibodies for Cancer Treatment
- (2008) Lawrence Fong et al. JOURNAL OF CLINICAL ONCOLOGY
- Expression of Indoleamine 2,3-Dioxygenase in Metastatic Pancreatic Ductal Adenocarcinoma Recruits Regulatory T Cells to Avoid Immune Detection
- (2008) Agnes Witkiewicz et al. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
- Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer
- (2008) M. Li et al. MOLECULAR CANCER THERAPEUTICS
- DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
- (2008) Timothy J. Ley et al. NATURE
- Engineered lentivector targeting of dendritic cells for in vivo immunization
- (2008) Lili Yang et al. NATURE BIOTECHNOLOGY
- Targeting RAS and PI3K in lung cancer
- (2008) Julian Downward NATURE MEDICINE
- Human dendritic cell maturation and activation by a heat-killed recombinant yeast (Saccharomyces cerevisiae) vector encoding carcinoembryonic antigen
- (2008) Cinzia Remondo et al. VACCINE
- Releasable PEGylation of proteins with customized linkers
- (2007) David Filpula et al. ADVANCED DRUG DELIVERY REVIEWS
- The Galα1,3Galβ1,4GlcNAc-R (α-Gal) epitope: A carbohydrate of unique evolution and clinical relevance
- (2007) Bruce A. Macher et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Mesothelin targeted cancer immunotherapy
- (2007) Raffit Hassan et al. EUROPEAN JOURNAL OF CANCER
- Recombinant Saccharomyces cerevisiae (yeast-CEA) as a potent activator of murine dendritic cells
- (2007) Michael B. Bernstein et al. VACCINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now