The unconventional expression of IL-15 and its role in NK cell homeostasis

Epidermal IL-15Rα acts as an endogenous antagonist of psoriasiform inflammation in mouse and man

(2013) Grégory Bouchaud et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcriptional Regulation of IL-15 Expression during Hematopoiesis

(2013) S. L. Colpitts et al.   JOURNAL OF IMMUNOLOGY

Circulating IL-15 exists as heterodimeric complex with soluble IL-15R  in human and mouse serum

(2012) C. Bergamaschi et al.   BLOOD

Regulating the immune system via IL-15 transpresentation

(2012) Eliseo F. Castillo et al.   CYTOKINE

Paracrine and Transpresentation Functions of IL-15 Are Mediated by Diverse Splice Versions of IL-15Rα in Human Monocytes and Dendritic Cells

(2012) Jürgen R. Müller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: The Role of IFN-  Receptor and MyD88 Signaling in Induction of IL-15 Expression In Vivo

(2012) S. L. Colpitts et al.   JOURNAL OF IMMUNOLOGY

Increased serum soluble IL-15R  levels in T-cell large granular lymphocyte leukemia

(2011) J. Chen et al.   BLOOD

Identification of the earliest NK-cell precursor in the mouse BM

(2011) S. Carotta et al.   BLOOD

CX3CR1 expression defines 2 KLRG1+ mouse NK-cell subsets with distinct functional properties and positioning in the bone marrow

(2011) G. Sciume et al.   BLOOD

Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens

(2011) R. W. DePaolo et al.   NATURE

Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation

(2010) E. F. Castillo et al.   BLOOD

Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15R  complexes

(2010) K. G. Elpek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maturation of mouse NK cells is a 4-stage developmental program

(2009) L. Chiossone et al.   BLOOD

Macrophage- and Dendritic-Cell-Derived Interleukin-15 Receptor Alpha Supports Homeostasis of Distinct CD8+ T Cell Subsets

(2009) Erwan Mortier et al.   IMMUNITY

Trans-Presentation of IL-15 by Intestinal Epithelial Cells Drives Development of CD8   IELs

(2009) L. J. Ma et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells Support the In Vivo Development and Maintenance of NK Cells via IL-15 Trans-Presentation

(2009) E. F. Castillo et al.   JOURNAL OF IMMUNOLOGY

Higher constitutive IL15Rα expression and lower IL-15 response threshold in coeliac disease patients

(2008) D. Bernardo et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation

(2008) Erwan Mortier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

(2008) Nicholas D. Huntington et al.   JOURNAL OF EXPERIMENTAL MEDICINE