The interplay between pathogen-associated and danger-associated molecular patterns: an inflammatory code in cancer?

Endogenous Damage-Associated Molecular Pattern Molecules at the Crossroads of Inflammation and Cancer

(2015) Geetha Srikrishna et al.   NEOPLASIA

HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines

(2014) Y. Sha et al.   JOURNAL OF IMMUNOLOGY

High Mobility Group Box 1 Protein Binding to Lipopolysaccharide Facilitates Transfer of Lipopolysaccharide to CD14 and Enhances Lipopolysaccharide-Mediated TNF-  Production in Human Monocytes

(2014) J. H. Youn et al.   JOURNAL OF IMMUNOLOGY

Stories of love and hate

(2013) Philip Rosenstiel   CURRENT OPINION IN GASTROENTEROLOGY

Cancer and Inflammation: An Old Intuition with Rapidly Evolving New Concepts

(2012) Giorgio Trinchieri   Annual Review of Immunology

Siglecs and Immune Regulation

(2012) Shiv Pillai et al.   Annual Review of Immunology

p53/HMGB1 Complexes Regulate Autophagy and Apoptosis

(2012) K. M. Livesey et al.   CANCER RESEARCH

Cancer Cell Secretion of the DAMP Protein HMGB1 Supports Progression in Malignant Mesothelioma

(2012) S. Jube et al.   CANCER RESEARCH

Optimizing Cancer Treatments to Induce an Acute Immune Response: Radiation Abscopal Effects, PAMPs, and DAMPs

(2012) C. M. Ludgate   CLINICAL CANCER RESEARCH

PAMPs and DAMPs: signal 0s that spur autophagy and immunity

(2012) Daolin Tang et al.   IMMUNOLOGICAL REVIEWS

Specificity of Antimicrobial Peptide LL-37 to Neutralize Periodontopathogenic Lipopolysaccharide Activity in Human Oral Fibroblasts

(2012) Wiroj Suphasiriroj et al.   JOURNAL OF PERIODONTOLOGY

Unknown

(2012) Hulda Hreggvidsdottir et al.   MOLECULAR MEDICINE

HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease

(2012) Helena Erlandsson Harris et al.   Nature Reviews Rheumatology

HMGB1 induces the overexpression of miR-222 and miR-221 and increases growth and motility in papillary thyroid cancer cells

(2012) STEFANIA MARDENTE et al.   ONCOLOGY REPORTS

Trial Watch

(2012) Lorenzo Galluzzi et al.   OncoImmunology

Inherited variation in pattern recognition receptors and cancer: dangerous liaisons?

(2012) Anton Kutikhin et al.   Cancer Management and Research

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

High Mobility Group Box 1 (HMGB1) Activates an Autophagic Response to Oxidative Stress

(2011) Daolin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1β release in human macrophages

(2011) Goran Petrovski et al.   Autophagy

Mycobacterium tuberculosis infection induces non-apoptotic cell death of human dendritic cells

(2011) Ruth CM Ryan et al.   BMC MICROBIOLOGY

Ten years of progress in vaccination against cancer: the need to counteract cancer evasion by dual targeting in future therapies

(2011) Yeranddy A. Alpizar et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Differential ex vivo and in vivo endotoxin tolerance kinetics following human endotoxemia*

(2011) Matthijs Kox et al.   CRITICAL CARE MEDICINE

Damage-associated molecular patterns (DAMPs) and mesenchymal stem cells: A matter of attraction and excitement

(2011) Vito Pistoia et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dysfunctional mitochondria contain endogenous high-affinity human Toll-like receptor 4 (TLR4) ligands and induce TLR4-mediated inflammatory reactions

(2011) Sally A. Nicholas et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

LL37 and Cationic Peptides Enhance TLR3 Signaling by Viral Double-stranded RNAs

(2011) Yvonne Lai et al.   PLoS One

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Inflammation and immune surveillance in cancer

(2011) Melvyn T. Chow et al.   SEMINARS IN CANCER BIOLOGY

High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts

(2011) Heidi Wähämaa et al.   ARTHRITIS RESEARCH & THERAPY

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

High-Mobility Group Box 1, Oxidative Stress, and Disease

(2010) Daolin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

Immunomodulation of monocyte-derived dendritic cells through ligation of tumor-produced mucins to Siglec-9

(2010) Mariko Ohta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Viruses and human cancer: From detection to causality

(2010) Ronit Sarid et al.   CANCER LETTERS

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

LPS-induced cytokine levels are repressed by elevated expression of HSP70 in rats: possible role of NF-κB

(2010) Karol Dokladny et al.   CELL STRESS & CHAPERONES

Microparticles as a source of extracellular DNA

(2010) David S. Pisetsky et al.   IMMUNOLOGIC RESEARCH

Endogenous HMGB1 regulates autophagy

(2010) Daolin Tang et al.   JOURNAL OF CELL BIOLOGY

CD14 is a coreceptor of Toll-like receptors 7 and 9

(2010) Christoph L. Baumann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells

(2010) L Liu et al.   LEUKEMIA

DAMPening Inflammation by Modulating TLR Signalling

(2010) A. M. Piccinini et al.   MEDIATORS OF INFLAMMATION

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

(2010) D Tang et al.   ONCOGENE

The antimicrobial peptide LL37 and its truncated derivatives potentiates proinflammatory cytokine induction by lipoteichoic acid in whole blood

(2010) Anna Gustafsson et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice

(2009) Maziyar Saberi et al.   Cell Metabolism

The role of Toll-like receptors in chronic inflammation

(2009) Stefan K. Drexler et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

(2009) Andrea Babelova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-1, Caspase-8, and Calpain Are Dispensable for IL-33 Release by Macrophages

(2009) T. Ohno et al.   JOURNAL OF IMMUNOLOGY

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation

(2009) Hulda Sigridur Hreggvidsdottir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HMGB1 loves company

(2009) Marco E. Bianchi   JOURNAL OF LEUKOCYTE BIOLOGY

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

(2009) Hideyuki Yanai et al.   NATURE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

CD24 and Siglec-10 Selectively Repress Tissue Damage-Induced Immune Responses

(2009) G.-Y. Chen et al.   SCIENCE

CD24-Siglec G/10 discriminates danger- from pathogen-associated molecular patterns

(2009) Yang Liu et al.   TRENDS IN IMMUNOLOGY

In vitro interaction between calf thymus DNA andEscherichia coli LPS in the presence of divalent cation Ca2+

(2008) Subrata Panja et al.   BIOPOLYMERS

Induction of Immunological Tolerance by Apoptotic Cells Requires Caspase-Dependent Oxidation of High-Mobility Group Box-1 Protein

(2008) Hirotaka Kazama et al.   IMMUNITY

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One

A clinical grade poly I:C-analogue (Ampligen®) promotes optimal DC maturation and Th1-type T cell responses of healthy donors and cancer patients in vitro

(2008) H. Navabi et al.   VACCINE

A review of the S100 proteins in cancer

(2007) I. Salama et al.   EJSO