Progranulin does not inhibit TNF and lymphotoxin-α signalling through TNF receptor 1

Deletion of progranulin exacerbates atherosclerosis in ApoE knockout mice

(2013) Ryota Kawase et al.   CARDIOVASCULAR RESEARCH

Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor

(2013) Nima Etemadi et al.   FEBS Journal

Progranulin deficiency exaggerates, whereas progranulin-derived Atsttrin attenuates, severity of dermatitis in mice

(2013) Yun-Peng Zhao et al.   FEBS LETTERS

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

(2013) James M. Murphy et al.   IMMUNITY

Regulation of TNF-α with a focus on rheumatoid arthritis

(2013) Eva AV Moelants et al.   IMMUNOLOGY AND CELL BIOLOGY

Progranulin Does Not Bind Tumor Necrosis Factor (TNF) Receptors and Is Not a Direct Regulator of TNF-Dependent Signaling or Bioactivity in Immune or Neuronal Cells

(2013) X. Chen et al.   JOURNAL OF NEUROSCIENCE

Progranulin: A Proteolytically Processed Protein at the Crossroads of Inflammation and Neurodegeneration

(2012) Basar Cenik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

(2012) Lauren Herl Martens et al.   JOURNAL OF CLINICAL INVESTIGATION

Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling

(2011) Boyoun Park et al.   IMMUNITY

Structure, Function, and Mechanism of Progranulin; the Brain and Beyond

(2011) Huishi Toh et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Loss of function mutations in the progranulin gene are related to pro-inflammatory cytokine dysregulation in frontotemporal lobar degeneration patients

(2011) Paola Bossù et al.   Journal of Neuroinflammation

The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice

(2011) W. Tang et al.   SCIENCE