siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo

TLR7 Is Involved in Sequence-Specific Sensing of Single-Stranded RNAs in Human Macrophages

(2014) M. P. Gantier et al.   JOURNAL OF IMMUNOLOGY

Double stranded RNA- relative to other TLR ligand-activated dendritic cells induce extremely polarized human Th1 responses

(2010) Risa K. Benwell et al.   CELLULAR IMMUNOLOGY

Enhancement of antitumor effect using dendritic cells activated with natural killer cells in the presence of Toll-like receptor agonist

(2010) Thanh Nhan Nguyen Pham et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Systemic delivery of E6/7 siRNA using novel lipidic particles and its application with cisplatin in cervical cancer mouse models

(2010) S Y Wu et al.   GENE THERAPY

Rational Design of Immunostimulatory siRNAs

(2010) Michael P Gantier et al.   MOLECULAR THERAPY

Targeting cyclin B1 inhibits proliferation and sensitizes breast cancer cells to taxol

(2009) Ilija Androic et al.   BMC CANCER

Toll-like Receptor 9 Activation of Signal Transducer and Activator of Transcription 3 Constrains Its Agonist-Based Immunotherapy

(2009) M. Kortylewski et al.   CANCER RESEARCH

Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice

(2009) Adam D. Judge et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunostimulatory RNA Blocks Suppression by Regulatory T Cells

(2009) D. Anz et al.   JOURNAL OF IMMUNOLOGY

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

(2009) Marcin Kortylewski et al.   NATURE BIOTECHNOLOGY

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

(2008) Mark E. Kleinman et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

(2008) Hendrik Poeck et al.   NATURE MEDICINE

Chemical Modification Patterns Compatible with High Potency Dicer-Substrate Small Interfering RNAs

(2008) Michael A. Collingwood et al.   OLIGONUCLEOTIDES

Development of a Novel Method for Formulating Stable siRNA-Loaded Lipid Particles for In vivo Use

(2008) Sherry Y. Wu et al.   PHARMACEUTICAL RESEARCH