Human B cells differentiate into granzyme B-secreting cytotoxic B lymphocytes upon incomplete T-cell help

IL-21-Induced Isotype Switching to IgG and IgA by Human Naive B Cells Is Differentially Regulated by IL-4

(2014) D. T. Avery et al.   JOURNAL OF IMMUNOLOGY

HIV-Specific IL-21 Producing CD4+ T Cells Are Induced in Acute and Chronic Progressive HIV Infection and Are Associated with Relative Viral Control

(2010) F. Y. Yue et al.   JOURNAL OF IMMUNOLOGY

HIV-1-Specific Interleukin-21+ CD4+ T Cell Responses Contribute to Durable Viral Control through the Modulation of HIV-Specific CD8+ T Cell Function

(2010) M. F. Chevalier et al.   JOURNAL OF VIROLOGY

Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion

(2009) B. Jahrsdorfer et al.   BLOOD

Targeting HSP90 for cancer therapy

(2009) D Mahalingam et al.   BRITISH JOURNAL OF CANCER

Human B Cells Secrete Granzyme B When Recognizing Viral Antigens in the Context of the Acute Phase Cytokine IL-21

(2009) M. Hagn et al.   JOURNAL OF IMMUNOLOGY

IL-21 Is Required to Control Chronic Viral Infection

(2009) H. Elsaesser et al.   SCIENCE

IL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro

(2008) A. Gowda et al.   BLOOD

Interleukin-21: biology and application to cancer therapy

(2008) David J Andorsky et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Regulation of tumor immunity: the role of NKT cells

(2008) Elena Ambrosino et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Interleukin 21: a cytokine/cytokine receptor system that has come of age

(2008) Warren J. Leonard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

NK cells and cancer immunosurveillance

(2008) I Waldhauer et al.   ONCOGENE

Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis

(2008) F. C. Kurschus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

(2007) Rosanne Spolski et al.   Annual Review of Immunology