Epithelium: the interplay between innate and Th2 immunity

The Human IL-17F/IL-17A Heterodimeric Cytokine Signals through the IL-17RA/IL-17RC Receptor Complex

(2014) J. F. Wright et al.   JOURNAL OF IMMUNOLOGY

IL-33, a Potent Inducer of Adaptive Immunity to Intestinal Nematodes

(2014) N. E. Humphreys et al.   JOURNAL OF IMMUNOLOGY

Identification of Functional Roles for Both IL-17RB and IL-17RA in Mediating IL-25-Induced Activities

(2014) E. A. Rickel et al.   JOURNAL OF IMMUNOLOGY

IL-33 Induces Antigen-Specific IL-5+ T Cells and Promotes Allergic-Induced Airway Inflammation Independent of IL-4

(2014) M. Kurowska-Stolarska et al.   JOURNAL OF IMMUNOLOGY

The Critical Role of Epithelial-Derived Act1 in IL-17- and IL-25-Mediated Pulmonary Inflammation

(2014) S. Swaidani et al.   JOURNAL OF IMMUNOLOGY

The Adaptor Protein CIKS/Act1 Is Essential for IL-25-Mediated Allergic Airway Inflammation

(2014) E. Claudio et al.   JOURNAL OF IMMUNOLOGY

IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes

(2009) I. Stuart Wood et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthma

(2009) Xiaojin Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Thymic stromal lymphopoietin is a critical mediator of IL-13-driven allergic inflammation

(2009) Masanori Miyata et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-γ production

(2009) Elvire Bourgeois et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T Cells in Asthma

(2009) Clare M. Lloyd et al.   IMMUNITY

Regulatory T Cells Reinforce Intestinal Homeostasis

(2009) Michael J. Barnes et al.   IMMUNITY

The Multifaceted Influence of the Mucosal Microflora on Mucosal Dendritic Cell Responses

(2009) Warren Strober   IMMUNITY

Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

(2009) Alexander U. Lüthi et al.   IMMUNITY

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

(2009) Steven A. Saenz et al.   IMMUNOLOGICAL REVIEWS

Interleukin-33 Is Biologically Active Independently of Caspase-1 Cleavage

(2009) Dominique Talabot-Ayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis

(2009) Betsy C. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proteases Induce Production of Thymic Stromal Lymphopoietin by Airway Epithelial Cells through Protease-Activated Receptor-2

(2009) H. Kouzaki et al.   JOURNAL OF IMMUNOLOGY

Regulation of Helminth-Induced Th2 Responses by Thymic Stromal Lymphopoietin

(2009) Thirumalai R. Ramalingam et al.   JOURNAL OF IMMUNOLOGY

Induction of Airway Hyperreactivity by IL-25 Is Dependent on a Subset of Invariant NKT Cells Expressing IL-17RB

(2009) P. Stock et al.   JOURNAL OF IMMUNOLOGY

The Essential Role of Single Ig IL-1 Receptor-Related Molecule/Toll IL-1R8 in Regulation of Th2 Immune Response

(2009) K. Bulek et al.   JOURNAL OF IMMUNOLOGY

IL-33 Activates Unprimed Murine Basophils Directly In Vitro and Induces Their In Vivo Expansion Indirectly by Promoting Hematopoietic Growth Factor Production

(2009) E. Schneider et al.   JOURNAL OF IMMUNOLOGY

IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38α-dependent pathway

(2009) Kelly M. Kroeger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Differentiation and function of pro-inflammatory Th17 cells

(2009) Chen Dong   MICROBES AND INFECTION

Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma

(2009) Sangeeta Goswami et al.   NATURE IMMUNOLOGY

A Commensal Helicobacter sp. of the Rodent Intestinal Flora Activates TLR2 and NOD1 Responses in Epithelial Cells

(2009) Nadia Chaouche-Drider et al.   PLoS One

Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function

(2009) J. C. Massacand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

(2009) C. Cayrol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Act1, a U-box E3 Ubiquitin Ligase for IL-17 Signaling

(2009) C. Liu et al.   Science Signaling

Nuclear Interleukin-33 Is Generally Expressed in Resting Endothelium but Rapidly Lost upon Angiogenic or Proinflammatory Activation

(2008) Axel M. Küchler et al.   AMERICAN JOURNAL OF PATHOLOGY

Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33

(2008) T. Pecaric-Petkovic et al.   BLOOD

CD4 T cells: fates, functions, and faults

(2008) J. Zhu et al.   BLOOD

Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2-polarizing conditions

(2008) J. Tanaka et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Initiation and maintenance of Th2 cell identity

(2008) Toshinori Nakayama et al.   CURRENT OPINION IN IMMUNOLOGY

NOD-like receptors (NLRs): bona fide intracellular microbial sensors

(2008) Michael H Shaw et al.   CURRENT OPINION IN IMMUNOLOGY

CD1d-restricted iNKT cells, the ‘Swiss-Army knife’ of the immune system

(2008) Jennifer L Matsuda et al.   CURRENT OPINION IN IMMUNOLOGY

The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33

(2008) Gaby Palmer et al.   CYTOKINE

An overview of IL-17 function and signaling

(2008) Sarah L. Gaffen   CYTOKINE

Structure–function relationships in the IL-17 receptor: Implications for signal transduction and therapy

(2008) Fang Shen et al.   CYTOKINE

The microbial and danger signals that activate Nod-like receptors

(2008) Szilvia Benko et al.   CYTOKINE

Mast cell regulation of epithelial TSLP expression plays an important role in the development of allergic rhinitis

(2008) Masanori Miyata et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD1d presentation of glycolipids

(2008) Anneliese O Speak et al.   IMMUNOLOGY AND CELL BIOLOGY

Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system

(2008) Y. Kondo et al.   INTERNATIONAL IMMUNOLOGY

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

(2008) W. Brett Cherry et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Commensal-dependent expression of IL-25 regulates the IL-23–IL-17 axis in the intestine

(2008) Colby Zaph et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-33 reduces the development of atherosclerosis

(2008) Ashley M. Miller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of inflammatory responses by IL-17F

(2008) Xuexian O. Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction of IL-33 expression and activity in central nervous system glia

(2008) Chad A. Hudson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils

(2008) Maho Suzukawa et al.   LABORATORY INVESTIGATION

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

(2008) Aurelien Trompette et al.   NATURE

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One

The Airway Epithelium is Central to the Pathogenesis of Asthma

(2008) Stephen T. Holgate   ALLERGOLOGY INTERNATIONAL