Autophagy activation by interferon-γ via the p38 mitogen-activated protein kinase signalling pathway is involved in macrophage bactericidal activity

Selective Roles of MAPKs during the Macrophage Response to IFN- 

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Observation of autophagosome maturation in the interferon-γ-primed and lipopolysaccharide-activated macrophages using a tandem fluorescent tagged LC3

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IFN-  Elicits Macrophage Autophagy via the p38 MAPK Signaling Pathway

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GBP5 Promotes NLRP3 Inflammasome Assembly and Immunity in Mammals

(2012) A. R. Shenoy et al.   SCIENCE

Autophagy in immunity and cell-autonomous defense against intracellular microbes

(2011) Vojo Deretic   IMMUNOLOGICAL REVIEWS

Autophagy facilitates an IFN-γ response and signal transduction

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Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

A Family of IFN- -Inducible 65-kD GTPases Protects Against Bacterial Infection

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Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria

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Autophagy, Immunity, and Microbial Adaptations

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Recognizing Macrophage Activation and Host Defense

(2009) John D. MacMicking   Cell Host & Microbe

Interferon-γ: A historical perspective

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Roles of phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase in the regulation of protein kinase C-α activation in interferon-γ-stimulated macrophages

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Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

The IRG proteins: A function in search of a mechanism

(2008) Jonathan Howard   IMMUNOBIOLOGY

Emerging themes in IFN-γ-induced macrophage immunity by the p47 and p65 GTPase families

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