Role of recombination activating genes in the generation of antigen receptor diversity and beyond

Mechanism of Fragility atBCL2Gene Minor Breakpoint Cluster Region during t(14;18) Chromosomal Translocation

(2012) Mridula Nambiar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional characterization of an active Rag-like transposase

(2012) Cary G Hencken et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Differential Reaction Kinetics, Cleavage Complex Formation, and Nonamer Binding Domain Dependence Dictate the Structure-Specific and Sequence-Specific Nuclease Activity of RAGs

(2011) Abani Kanta Naik et al.   JOURNAL OF MOLECULAR BIOLOGY

The RAG2 C terminus suppresses genomic instability and lymphomagenesis

(2011) Ludovic Deriano et al.   NATURE

How does DNA break during chromosomal translocations?

(2011) M. Nambiar et al.   NUCLEIC ACIDS RESEARCH

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci

(2010) Yanhong Ji et al.   CELL

Cytosines, but Not Purines, Determine Recombination Activating Gene (RAG)-induced Breaks on Heteroduplex DNA Structures

(2010) Abani Kanta Naik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma

(2010) Mridula Nambiar et al.   NUCLEIC ACIDS RESEARCH

A Non-Sequence-Specific DNA Binding Mode of RAG1 Is Inhibited by RAG2

(2009) Shuying Zhao et al.   JOURNAL OF MOLECULAR BIOLOGY

H3K4me3 Stimulates the V(D)J RAG Complex for Both Nicking and Hairpinning in trans in Addition to Tethering in cis: Implications for Translocations

(2009) Noriko Shimazaki et al.   MOLECULAR CELL

Mechanism and Regulation of Class Switch Recombination

(2008) Janet Stavnezer et al.   Annual Review of Immunology

V(D)J Recombinase Binding and Cleavage of Cryptic Recombination Signal Sequences Identified from Lymphoid Malignancies

(2008) Ming Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY