Tim-4 inhibition of T-cell activation and T helper type 17 differentiation requires both the immunoglobulin V and mucin domains and occurs via the mitogen-activated protein kinase pathway

Loss of STAT3 in CD4 + T Cells Prevents Development of Experimental Autoimmune Diseases

(2014) Xuebin Liu et al.   JOURNAL OF IMMUNOLOGY

TIM-4 Expressed on APCs Induces T Cell Expansion and Survival

(2014) R. Rodriguez-Manzanet et al.   JOURNAL OF IMMUNOLOGY

T Cell Ig and Mucin Domain-1-Mediated T Cell Activation Requires Recruitment and Activation of Phosphoinositide 3-Kinase

(2014) A. J. de Souza et al.   JOURNAL OF IMMUNOLOGY

Pharmacologic Inhibition of MEK–ERK Signaling Enhances Th17 Differentiation

(2010) Andy Hee-Meng Tan et al.   JOURNAL OF IMMUNOLOGY

Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages

(2010) K. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

(2010) R. Rodriguez-Manzanet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Phosphatidylserine Receptor TIM-4 Does Not Mediate Direct Signaling

(2009) Daeho Park et al.   CURRENT BIOLOGY

TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines

(2009) William D. Hastings et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

ERK-Dependent T Cell Receptor Threshold Calibration in Rheumatoid Arthritis

(2009) K. Singh et al.   JOURNAL OF IMMUNOLOGY

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

(2009) X. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Galectin-9 Significantly Prolongs the Survival of Fully Mismatched Cardiac Allografts in Mice

(2009) Wentao He et al.   TRANSPLANTATION

STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease

(2008) S. X. Lu et al.   BLOOD

Induction, function and regulation of IL-17-producing T cells

(2008) Kingston H. G. Mills   EUROPEAN JOURNAL OF IMMUNOLOGY

Bimodal regulation of T cell-mediated immune responses by TIM-4

(2008) M. Mizui et al.   INTERNATIONAL IMMUNOLOGY