Regulation of NF-κB by the CARD proteins

Cell Type-Specific Regulation of ITAM-Mediated NF- B Activation by the Adaptors, CARMA1 and CARD9

(2014) H. Hara et al.   JOURNAL OF IMMUNOLOGY

Differential Use of CARD9 by Dectin-1 in Macrophages and Dendritic Cells

(2014) H. S. Goodridge et al.   JOURNAL OF IMMUNOLOGY

Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies

(2012) Kian-Huat Lim et al.   IMMUNOLOGICAL REVIEWS

The atypical PKCs in inflammation: NF-κB and beyond

(2012) Maria T. Diaz-Meco et al.   IMMUNOLOGICAL REVIEWS

CARMA3 is Crucial for EGFR-Induced Activation of NF- B and Tumor Progression

(2011) T. Jiang et al.   CANCER RESEARCH

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Mutations of CARD11 but not TNFAIP3 may activate the NF-κB pathway in primary CNS lymphoma

(2010) Manuel Montesinos-Rongen et al.   ACTA NEUROPATHOLOGICA

Oncogenic CARD11 Mutations Induce Hyperactive Signaling by Disrupting Autoinhibition by the PKC-Responsive Inhibitory Domain

(2010) Rebecca L. Lamason et al.   BIOCHEMISTRY

NF-κB signaling pathways regulated by CARMA family of scaffold proteins

(2010) Marzenna Blonska et al.   CELL RESEARCH

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

The CARMA3-Bcl10-MALT1 Signalosome Promotes Angiotensin II-dependent Vascular Inflammation and Atherogenesis

(2010) Linda M. McAllister-Lucas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombin-dependent NF-κB Activation and Monocyte/Endothelial Adhesion Are Mediated by the CARMA3·Bcl10·MALT1 Signalosome

(2010) Phillip C. Delekta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CARD9 Mediates Dectin-2-induced IκBα Kinase Ubiquitination Leading to Activation of NF-κB in Response to Stimulation by the Hyphal Form ofCandida albicans

(2010) Liangkuan Bi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Asymmetric Recruitment of cIAPs by TRAF2

(2010) Peter D. Mace et al.   JOURNAL OF MOLECULAR BIOLOGY

CXCL12/SDF‐1α Activates NF‐κB and Promotes Oral Cancer Invasion through the Carma3/Bcl10/Malt1 Complex

(2010) Aasia O Rehman et al.   International Journal of Oral Science

MEKK3 is required for lysophosphatidic acid-induced NF-κB activation

(2009) Wenjing Sun et al.   CELLULAR SIGNALLING

The Dectin-2 family of C-type lectins in immunity and homeostasis

(2009) Lisa M. Graham et al.   CYTOKINE

COP9 signalosome controls the Carma1–Bcl10–Malt1 complex upon T-cell stimulation

(2009) Verena Welteke et al.   EMBO REPORTS

Cellular Inhibitors of Apoptosis cIAP1 and cIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2

(2009) Mathieu J.M. Bertrand et al.   IMMUNITY

CARMA1-mediated NF-κB and JNK activation in lymphocytes

(2009) Marzenna Blonska et al.   IMMUNOLOGICAL REVIEWS

Platelet-activating factor-induced NF-κB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent

(2009) Alip Borthakur et al.   INFLAMMATORY BOWEL DISEASES

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adjuvanticity of a synthetic cord factor analogue for subunitMycobacterium tuberculosisvaccination requires FcRγ–Syk–Card9–dependent innate immune activation

(2009) Kerstin Werninghaus et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Serine 649 Phosphorylation within the Protein Kinase C-Regulated Domain Down-Regulates CARMA1 Activity in Lymphocytes

(2009) M. E. Moreno-Garcia et al.   JOURNAL OF IMMUNOLOGY

MAGUK-Controlled Ubiquitination of CARMA1 Modulates Lymphocyte NF- B Activity

(2009) M. E. Moreno-Garcia et al.   MOLECULAR AND CELLULAR BIOLOGY

Casein kinase 1α governs antigen-receptor-induced NF-κB activation and human lymphoma cell survival

(2009) Nicolas Bidère et al.   NATURE

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production

(2009) Hendrik Poeck et al.   NATURE IMMUNOLOGY

CARD9 facilitates microbe-elicited production of reactive oxygen species by regulating the LyGDI-Rac1 complex

(2009) Weihui Wu et al.   NATURE IMMUNOLOGY

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of innate immunity

(2009) Paola M. Barral et al.   PHARMACOLOGY & THERAPEUTICS

Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1

(2009) S. Kojo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of CARMA1 by HPK1 is critical for NF- B activation in T cells

(2009) D. Brenner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CARD9 versus CARMA1 in innate and adaptive immunity

(2009) Hiromitsu Hara et al.   TRENDS IN IMMUNOLOGY

NOD-Like Receptors: Role in Innate Immunity and Inflammatory Disease

(2008) Grace Chen et al.   Annual Review of Pathology-Mechanisms of Disease

Structural Mechanism of RNA Recognition by the RIG-I-like Receptors

(2008) Mitsutoshi Yoneyama et al.   IMMUNITY

CXCL8/IL8 Stimulates Vascular Endothelial Growth Factor (VEGF) Expression and the Autocrine Activation of VEGFR2 in Endothelial Cells by Activating NFκB through the CBM (Carma3/Bcl10/Malt1) Complex

(2008) Daniel Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T-Cell Receptor-Induced NF- B Activation Is Negatively Regulated by E3 Ubiquitin Ligase Cbl-b

(2008) G. Qiao et al.   MOLECULAR AND CELLULAR BIOLOGY

IAPs: What's in a Name?

(2008) Srinivasa M. Srinivasula et al.   MOLECULAR CELL

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

(2008) Mathieu J.M. Bertrand et al.   MOLECULAR CELL

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY

RIG-I and dsRNA-Induced IFNβ Activation

(2008) Stéphane Hausmann et al.   PLoS One

NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF- B activation

(2008) C.-J. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

(2008) G. Lenz et al.   SCIENCE

C-type lectin receptors in antifungal immunity

(2007) Janet A. Willment et al.   TRENDS IN MICROBIOLOGY