T cell recognition of weak ligands: roles of signaling, receptor number, and affinity

TCR Antagonism by Peptide Requires High TCR Expression

(2014) D. S. Jones et al.   JOURNAL OF IMMUNOLOGY

Induction of Anergy by Antibody Blockade of TCR in Myelin Oligodendrocyte Glycoprotein-Specific Cells

(2014) H. A. Wasserman et al.   JOURNAL OF IMMUNOLOGY

MHC Variant Peptide-Mediated Anergy of Encephalitogenic T Cells Requires SHP-1

(2014) H. A. Wasserman et al.   JOURNAL OF IMMUNOLOGY

Two-Stage Cooperative T Cell Receptor-Peptide Major Histocompatibility Complex-CD8 Trimolecular Interactions Amplify Antigen Discrimination

(2011) Ning Jiang et al.   IMMUNITY

High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+T cell responses

(2011) Joseph J. Sabatino et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stimulation of Naive CD8 + T Cells by a Variant Viral Epitope Induces Activation and Enhanced Apoptosis

(2010) Rebecca M. Ream et al.   JOURNAL OF IMMUNOLOGY

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness

(2010) Jun Huang et al.   NATURE

TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity

(2010) Johannes B. Huppa et al.   NATURE

Viral infection triggers central nervous system autoimmunity via activation of CD8+ T cells expressing dual TCRs

(2010) Qingyong Ji et al.   NATURE IMMUNOLOGY

Natural epitope variants of the hepatitis C virus impair cytotoxic T lymphocyte activity

(2010) Shuping Wang   WORLD JOURNAL OF GASTROENTEROLOGY

A unique unresponsive CD4+ T cell phenotype post TCR antagonism

(2009) Lindsay J. Edwards et al.   CELLULAR IMMUNOLOGY

No Effect of the Altered Peptide Ligand NBI-6024 on  -Cell Residual Function and Insulin Needs in New-Onset Type 1 Diabetes

(2009) M. Walter et al.   DIABETES CARE

CD8+ T Cell Responses to a Viral Escape Mutant Epitope: Active Suppression via Altered SHP-1 Activity

(2009) F. J. Schnell et al.   JOURNAL OF IMMUNOLOGY

Naturally Occurring Altered Peptide Ligands Control Salmonella-Specific CD4+ T Cell Proliferation, IFN-  Production, and Protective Potency

(2009) T. M. Johanns et al.   JOURNAL OF IMMUNOLOGY

Protein tyrosine phosphatase inhibition induces anti-tumor activity: Evidence of Cdk2/p27kip1 and Cdk2/SHP-1 complex formation in human ovarian cancer cells

(2008) Danielle Caron et al.   CANCER LETTERS

Activation of Cdk2 Stimulates Proteasome-dependent Truncation of Tyrosine Phosphatase SHP-1 in Human Proliferating Intestinal Epithelial Cells

(2008) Mélanie Simoneau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY