Article
Biochemistry & Molecular Biology
Qihua Pan, Junzhi Luo, Yuewen Jiang, Zhi Wang, Ke Lu, Tiansheng Chen
Summary: This study demonstrates the successful application of a poly-transfer RNA-gRNA system in fish to achieve gene editing using the CRISPR/Cas9 system, which is a significant step towards potential use of this system in medaka and other teleosts.
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B
(2022)
Article
Ecology
Ke He, Ying Zhu, Shang-Chen Yang, Qing Ye, Sheng-Guo Fang, Qiu-Hong Wan
Summary: The study on the MHC gene structure of the Chinese alligator reveals the presence of Class I and Class II subregions, a unique CD1 subregion, multiple groups of MHC class I and class II duplicated loci, and a mechanism for polymorphism in antigen presentation.
FRONTIERS IN ECOLOGY AND EVOLUTION
(2022)
Article
Multidisciplinary Sciences
Arnaud Gaigher, Alessia Rota, Fabiana Neves, Antonio Munoz-Merida, Javier Blasco-Arostegui, Tereza Almeida, Ana Verissimo
Summary: The major histocompatibility complex (MHC) is a gene family responsible for pathogen detection and immune response initiation. The MHC is characterized by duplication, natural selection, recombination, and high genetic diversity. This study focused on the MHC II beta diversity in the small-spotted catshark and found three MHC II beta loci with expression in different tissues. The analysis also revealed high sequence diversity, positive selection, recombination, and potential copy number variation in the MHC II beta genes of the small-spotted catshark.
SCIENTIFIC REPORTS
(2023)
Article
Fisheries
Bingchao Wang, Fangzheng Zhu, Zechao Shi, Zhenyu Huang, Ruhan Sun, Qingchao Wang, Ouyang Gang, Wei Ji
Summary: In this study, the mhc IIA and mhc IIB genes of yellow catfish Pelteobagrus fulvidraco were cloned and characterized. Similar gene structure and expression patterns were observed for both mhc IIA and mhc IIB, and they play an important role in the anti-infection process.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Jose Fernando Lopez-Olmeda, Haiyu Zhao, Markus Reischl, Christian Pylatiuk, Tyrone Lucon-Xiccato, Felix Loosli, Nicholas S. Foulkes
Summary: Day length and seasonal cycles affect various aspects of animal biology. In a study on medaka, it was found that photoperiod has sex-specific effects on learning performance of the fish. Under long photoperiod, mixed-sex groups learned quickly while males showed a learning deficit, but under a short photoperiod where mating is not possible, male performance improved.
Article
Environmental Sciences
Xian Qin, Keng Po Lai, Rudolf Shiu Sun Wu, Richard Yuen Chong Kong
Summary: This study investigated the effects of continuous exposure to 17 alpha-ethinylestradiol (EE2) on reproductive performance in marine medaka fish. The results showed that continuous EE2 exposure reduced fecundity and sperm motility, and caused dysregulation in testicular transcriptome. Key genes identified in this study can serve as biomarkers for assessing EE2-induced reduction in sperm motility.
MARINE POLLUTION BULLETIN
(2022)
Article
Biochemistry & Molecular Biology
Shogo Hori, Naoki Sakamoto, Osamu Saitoh
Summary: The olTRPV4 in medaka fish functions as an osmosensor and plays important roles in the adaption mechanism to changes in salinity environment. It can be activated by cold, hot, and hypotonic solution, with differential expression in gills and brains of sea water-acclimated medaka.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2022)
Article
Toxicology
Lingyu Liu, Leonie Hobohm, Felix Bredendiek, Alexander Froschauer, Oliver Zierau, Maria Kristina Parr, Annekathrin M. Keiler
Summary: This study investigates the use of medaka embryos as an alternative model for studying human-like metabolism. The results show that medaka embryos can produce metabolites similar to human biotransformation, indicating its potential as a promising model. Additionally, the developmental parameters of fish embryos enable the assessment of toxicity simultaneously.
ARCHIVES OF TOXICOLOGY
(2022)
Article
Environmental Sciences
Yuki Takai, Hideaki Tokusumi, Moeko Sato, Daishi Inoue, Kun Chen, Takumi Takamura, Shintaro Enoki, Yu Ueno, Ik Joon Kang, Yohei Shimasaki, Xuchun Qiu, Yuji Oshima
Summary: This laboratory study evaluated the combined effect of polystyrene microplastics and diazepam on the social behavior of medaka. The findings suggest that the presence of microplastics can enhance the adverse effects of pollutants on the social behavior of aquatic organisms.
Article
Environmental Sciences
Sourav Chakraborty, Manthi Dissanayake, Julia Godwin, Xuegeng Wang, Ramji Kumar Bhandari
Summary: Environmental chemical exposures can result in the transgenerational passage of liver defects in subsequent generations, even in an uncontaminated environment. Ancestral exposure to BPA can lead to transgenerational metabolic diseases, with the severity of NAFLD phenotype being sexually dimorphic. Developing methods and strategies to mitigate the transgenerational onset of metabolic diseases is crucial for protecting future generations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Physiology
Elizabeth DiBona, Lee J. Pinnell, Annika Heising-Huang, Simon Geist, Jeffrey W. Turner, Frauke Seemann
Summary: Microplastic pollution is a global concern for environmental health, aquaculture, and fisheries. Studies have shown that microplastic ingestion may impact fish health, specifically causing intestinal damage and microbiota imbalances. Although no imminent threat to fish health was found at current environmental levels of microplastics, close monitoring of important spawning grounds is recommended.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Kazuki Kodera, Hideaki Matsui
Summary: In recent years, small fishes such as zebrafish, medaka, and turquoise killifish have been recognized as excellent model animals for studying human neurological disorders. These fishes have high genetic and tissue structure homology with humans, as well as unique features that make them suitable for experiments and analysis. They have been extensively used in neurology research, particularly in uncovering the mechanisms of neurodegenerative diseases and neurodevelopmental disorders. Zebrafish and medaka, in particular, have played a significant role in understanding diseases like Parkinson's and Autism Spectrum Disorder. Turquoise killifish has emerged as a unique model animal for aging research and age-related neurological diseases. These small fishes have great potential in improving our understanding of neurological disorders in humans.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Tao Xiang, Xianghong Dong, Tao Ju, Lei Shi, Gael Grenouillet
Summary: Over the past centuries, freshwater fish introductions and extinctions have posed major crises to various water bodies in China, but their consequences on freshwater fish biodiversity remain understudied. This study evaluated the temporal changes in taxonomic, functional, and phylogenetic facets of fish biodiversity across Chinese basins and identified the drivers behind these changes. The results showed extreme changes in the biodiversity facets of fish assemblages in Northwest and Southwest China, largely driven by environmental factors. Given the ongoing homogenization of fish faunas in the majority of China's water bodies, targeted conservation and management strategies are needed.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Multidisciplinary Sciences
Tyrone Lucon-Xiccato, Felix Loosli, Francesca Conti, Nicholas S. Foulkes, Cristiano Bertolucci
Summary: This study analysed the behaviour of medaka in anxiety-like and sociability tests and found that it showed similarities with other teleosts in some tests but also exhibited differences. A comparison with zebrafish under the same conditions revealed significant variations in behavioural responses, indicating that medaka responds differently to experimental settings compared to other fish models.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Ena Kaneko, Hinako Sato, Shoji Fukamachi
Summary: The researchers conducted a three-chamber experiment on medaka and found that sexual preference could not be reliably evaluated, whether through manual counting or the three-chamber strategy. Although some intriguing observations were made during the experiment, further research is needed to understand the implications of these results.