Animal Models of Fear Relapse

Effects of the Emotion System on Adaptive Behavior

(2013) Jarl Giske et al.   AMERICAN NATURALIST

Disruption of social bonds induces behavioral and physiological dysregulation in male and female prairie voles

(2013) Neal McNeal et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

A sensory-enhanced context allows renewal of an extinguished fear response in the infant rat

(2013) D.A. Revillo et al.   BEHAVIOURAL BRAIN RESEARCH

Chronic psychosocial stress makes rats more ‘pessimistic’ in the ambiguous-cue interpretation paradigm

(2013) Justyna Papciak et al.   BEHAVIOURAL BRAIN RESEARCH

Sex differences and estrous cycle in female rats interact with the effects of fluoxetine treatment on fear extinction

(2013) K. Lebrón-Milad et al.   BEHAVIOURAL BRAIN RESEARCH

On the differences in degree of renewal produced by the different renewal designs

(2013) Cody W. Polack et al.   BEHAVIOURAL PROCESSES

The Brain-Derived Neurotrophic Factor Val66Met Polymorphism Predicts Response to Exposure Therapy in Posttraumatic Stress Disorder

(2013) Kim L. Felmingham et al.   BIOLOGICAL PSYCHIATRY

Differential impact of the first and second wave of a stress response on subsequent fear conditioning in healthy men

(2013) Martin I. Antov et al.   BIOLOGICAL PSYCHOLOGY

Recent Progress in Understanding the Pathophysiology of Post-Traumatic Stress Disorder

(2013) Christopher R. Bailey et al.   CNS DRUGS

Serotonergic innervation of the amygdala: targets, receptors, and implications for stress and anxiety

(2013) Esther Asan et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Effects of stressors in adolescence on learning and memory in rodent models

(2013) Matthew R. Green et al.   HORMONES AND BEHAVIOR

Genetic approaches to understanding post-traumatic stress disorder

(2013) Lynn M. Almli et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The relationship between mental and physical health: Insights from the study of heart rate variability

(2013) Andrew H. Kemp et al.   INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY

HPA axis changes during the initial phase of psychosocial stressor exposure in male mice

(2013) Nicole Uschold-Schmidt et al.   JOURNAL OF ENDOCRINOLOGY

Extinction of reinstated or ABC renewed fear responses renders them resistant to subsequent ABA renewal.

(2013) Nathan M. Holmes et al.   JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL LEARNING AND COGNITION

Enriched Early Life Experiences Reduce Adult Anxiety-Like Behavior in Rats: A Role for Insulin-Like Growth Factor 1

(2013) S. Baldini et al.   JOURNAL OF NEUROSCIENCE

Extinction of conditioned fear is better learned and recalled in the morning than in the evening

(2013) Edward F. Pace-Schott et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Temporal dynamics of recovery from extinction shortly after extinction acquisition

(2013) G. E. Archbold et al.   LEARNING & MEMORY

Activation of BDNF signaling prevents the return of fear in female mice

(2013) D. Baker-Andresen et al.   LEARNING & MEMORY

Sex differences in the generalization of fear as a function of retention intervals

(2013) J. Lynch et al.   LEARNING & MEMORY

Memory retrieval before or after extinction reduces recovery of fear in adolescent rats

(2013) K. D. Baker et al.   LEARNING & MEMORY

Sleep aromatherapy curbs conditioned fear

(2013) John T Wixted   NATURE NEUROSCIENCE

The contextual brain: implications for fear conditioning, extinction and psychopathology

(2013) Stephen Maren et al.   NATURE REVIEWS NEUROSCIENCE

Prefrontal high-frequency stimulation prevents sub-conditioning procedure-provoked, but not acute stress-provoked, reemergence of extinguished fear

(2013) Xigeng Zheng et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Psychological and neural mechanisms of experimental extinction: A selective review

(2013) Andrew R. Delamater et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Fear of the unexpected: Hippocampus mediates novelty-induced return of extinguished fear in rats

(2013) Stephen Maren   NEUROBIOLOGY OF LEARNING AND MEMORY

Hippocampal activation during extinction learning predicts occurrence of the renewal effect in extinction recall

(2013) Silke Lissek et al.   NEUROIMAGE

The Brain on Stress: Vulnerability and Plasticity of the Prefrontal Cortex over the Life Course

(2013) Bruce S. McEwen et al.   NEURON

Learning not to Fear: Neural Correlates of Learned Safety

(2013) Eryan Kong et al.   NEUROPSYCHOPHARMACOLOGY

Translational developmental studies of stress on brain and behavior: Implications for adolescent mental health and illness?

(2013) M. Malter Cohen et al.   NEUROSCIENCE

Stress and excitatory synapses: From health to disease

(2013) W. Timmermans et al.   NEUROSCIENCE

An animal model of stress-induced cardiomyopathy utilizing the social defeat paradigm

(2013) Cyrilla H. Wideman et al.   PHYSIOLOGY & BEHAVIOR

Sex differences and chronic stress effects on the neural circuitry underlying fear conditioning and extinction

(2013) Mollee R. Farrell et al.   PHYSIOLOGY & BEHAVIOR

Anxiety-like, novelty-seeking and memory/learning behavioral traits in male Wistar rats submitted to early weaning

(2013) Mabel Carneiro Fraga et al.   PHYSIOLOGY & BEHAVIOR

A new stress model, a scream sound, alters learning and monoamine levels in rat brain

(2013) Lili Hu et al.   PHYSIOLOGY & BEHAVIOR

Prefrontal microcircuit underlies contextual learning after hippocampal loss

(2013) M. Zelikowsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress increases aversive prediction error signal in the ventral striatum

(2013) O. J. Robinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single dose of L-dopa makes extinction memories context-independent and prevents the return of fear

(2013) J. Haaker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anxiogenic effects of brief swim stress are sensitive to stress history

(2013) John P. Christianson et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Stress differentially affects fear conditioning in men and women

(2013) Christian Josef Merz et al.   PSYCHONEUROENDOCRINOLOGY

Using Neurobiological Measures to Predict and Assess Treatment Outcome of Psychotherapy in Posttraumatic Stress Disorder: Systematic Review

(2013) Jasper B. Zantvoord et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Translational Approaches to Anxiety: Focus on Genetics, Fear Extinction and Brain Imaging

(2013) Angelika Erhardt et al.   Current Psychiatry Reports

A single gene defect causing claustrophobia

(2013) A El-Kordi et al.   Translational Psychiatry

A Dialogue between the Immune System and Brain, Spoken in the Language of Serotonin

(2012) Nicole L. Baganz et al.   ACS Chemical Neuroscience

Prior stress interferes with the anxiolytic effect of exercise in c57bl/6j mice.

(2012) Brendan D. Hare et al.   BEHAVIORAL NEUROSCIENCE

Short- and long-term consequences of stressor controllability in adolescent rats

(2012) Kenneth H. Kubala et al.   BEHAVIOURAL BRAIN RESEARCH

Cholinergic Blockade Frees Fear Extinction from Its Contextual Dependency

(2012) Moriel Zelikowsky et al.   BIOLOGICAL PSYCHIATRY

Rapid Remission of Conditioned Fear Expression with Extinction Training Paired with Vagus Nerve Stimulation

(2012) David F. Peña et al.   BIOLOGICAL PSYCHIATRY

Extinction, generalization, and return of fear: A critical review of renewal research in humans

(2012) Bram Vervliet et al.   BIOLOGICAL PSYCHOLOGY

Pharmacological Innovations for Posttraumatic Stress Disorder and Medication- Enhanced Psychotherapy

(2012) Boadie W. Dunlop et al.   CURRENT PHARMACEUTICAL DESIGN

TOWARD AN ACCOUNT OF CLINICAL ANXIETY PREDICATED ON BASIC, NEURALLY MAPPED MECHANISMS OF PAVLOVIAN FEAR-LEARNING: THE CASE FOR CONDITIONED OVERGENERALIZATION

(2012) Shmuel Lissek   DEPRESSION AND ANXIETY

EARLY INTERVENTIONS FOR PTSD: A REVIEW

(2012) Megan C. Kearns et al.   DEPRESSION AND ANXIETY

Targeting memory processes with drugs to prevent or cure PTSD

(2012) Christopher K. Cain et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Agomelatine Prevents Relapse in Generalized Anxiety Disorder

(2012) Dan J. Stein et al.   JOURNAL OF CLINICAL PSYCHIATRY

Low-Frequency Stimulation Depresses the Primate Anterior-Cingulate-Cortex and Prevents Spontaneous Recovery of Aversive Memories

(2012) O. Klavir et al.   JOURNAL OF NEUROSCIENCE

Review of exposure therapy: A gold standard for PTSD treatment

(2012) Sheila A. M. Rauch et al.   JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT

Single prolonged stress disrupts retention of extinguished fear in rats

(2012) D. Knox et al.   LEARNING & MEMORY

Gating of Fear in Prelimbic Cortex by Hippocampal and Amygdala Inputs

(2012) Francisco Sotres-Bayon et al.   NEURON

Neural Mechanisms of Stress Resilience and Vulnerability

(2012) Tamara B. Franklin et al.   NEURON

Rethinking the Emotional Brain

(2012) Joseph LeDoux   NEURON

Effects of chronic plus acute prolonged stress on measures of coping style, anxiety, and evoked HPA-axis reactivity

(2012) Megan K. Roth et al.   NEUROPHARMACOLOGY

A current overview of cannabinoids and glucocorticoids in facilitating extinction of aversive memories: Potential extinction enhancers

(2012) Rafael Mariano de Bitencourt et al.   NEUROPHARMACOLOGY

Distinct mechanisms mediate the reinstatement and spontaneous recovery of extinguished fear in rats

(2012) Xiang Ma et al.   NEUROSCIENCE LETTERS

Medial Prefrontal Cortex

(2012) Mouna Maroun   NEUROSCIENTIST

Functional anatomy of neural circuits regulating fear and extinction

(2012) E. Knapska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute psychosocial stress: Does the emotional stress response correspond with physiological responses?

(2012) Jana Campbell et al.   PSYCHONEUROENDOCRINOLOGY

Stress modulation of reconsolidation

(2012) Irit Akirav et al.   PSYCHOPHARMACOLOGY

Stress-enhanced fear learning in rats is resistant to the effects of immediate massed extinction

(2012) Virginia A. Long et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Emotional arousal and multiple memory systems in the mammalian brain

(2012) Mark G. Packard et al.   Frontiers in Behavioral Neuroscience

Prototypical Components of Honeybee Homing Flight Behavior Depend on the Visual Appearance of Objects Surrounding the Goal

(2012) Elke Braun et al.   Frontiers in Behavioral Neuroscience

One's sex, sleep, and posttraumatic stress disorder

(2012) Ihori Kobayashi et al.   Biology of Sex Differences

Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

(2011) Mohammed R. Milad et al.   Annual Review of Psychology

Prolonged exposure therapy: past, present, and future

(2011) Edna B. Foa   DEPRESSION AND ANXIETY

Enhanced stress responses in adolescent versus adult rats exposed to cues of predation threat, and peer interaction as a predictor of adult defensiveness

(2011) Lisa D. Wright et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Context Processing in Aging: Older Mice Are Impaired in Renewal of Extinguished Fear

(2011) Matthew J. Sanders   EXPERIMENTAL AGING RESEARCH

Prolonged exposure therapy for post-traumatic stress disorder: a review of evidence and dissemination

(2011) Carmen P McLean et al.   Expert Review of Neurotherapeutics

A neuroimmunological perspective on anxiety disorders

(2011) Ruihua Hou et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Effects of Elevation of Brain Magnesium on Fear Conditioning, Fear Extinction, and Synaptic Plasticity in the Infralimbic Prefrontal Cortex and Lateral Amygdala

(2011) N. Abumaria et al.   JOURNAL OF NEUROSCIENCE

Medial prefrontal cortex activation facilitates re-extinction of fear in rats

(2011) C.-h. Chang et al.   LEARNING & MEMORY

Amygdala circuitry mediating reversible and bidirectional control of anxiety

(2011) Kay M. Tye et al.   NATURE

Noradrenergic enhancement of associative fear memory in humans

(2011) Marieke Soeter et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

How specific is specific phobia? Different neural response patterns in two subtypes of specific phobia

(2011) Ulrike Lueken et al.   NEUROIMAGE

Seeking a Spotless Mind: Extinction, Deconsolidation, and Erasure of Fear Memory

(2011) Stephen Maren   NEURON

Cannabinoids Prevent the Development of Behavioral and Endocrine Alterations in a Rat Model of Intense Stress

(2011) Eti Ganon-Elazar et al.   NEUROPSYCHOPHARMACOLOGY

Prenatal stress induces long term stress vulnerability, compromising stress response systems in the brain and impairing extinction of conditioned fear after adult stress

(2011) M.K. Green et al.   NEUROSCIENCE

Stress-induced enhancement of fear conditioning and sensitization facilitates extinction-resistant and habituation-resistant fear behaviors in a novel animal model of posttraumatic stress disorder

(2011) Michael J. Corley et al.   PHYSIOLOGY & BEHAVIOR

How the Neurocircuitry and Genetics of Fear Inhibition May Inform Our Understanding of PTSD

(2010) Tanja Jovanovic et al.   AMERICAN JOURNAL OF PSYCHIATRY

Role of the medial prefrontal cortex in coping and resilience

(2010) Steven F. Maier et al.   BRAIN RESEARCH

Evidence for the persistence of contextual fear memories following immediate extinction

(2010) Georgina E. B. Archbold et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neuronal circuits of fear extinction

(2010) Cyril Herry et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Increased spontaneous recovery with increases in conditioned stimulus alone exposures.

(2010) Hiu Tin Leung et al.   JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL LEARNING AND COGNITION

Erasing Fear Memories with Extinction Training

(2010) G. J. Quirk et al.   JOURNAL OF NEUROSCIENCE

Impact of predatory threat on fear extinction in Lewis rats

(2010) S. Goswami et al.   LEARNING & MEMORY

Stress enhancement of fear learning in mice is dependent upon stressor type: Effects of sex and ovarian hormones

(2010) Matthew J. Sanders et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Fibroblast Growth Factor-2 Enhances Extinction and Reduces Renewal of Conditioned Fear

(2010) Bronwyn M Graham et al.   NEUROPSYCHOPHARMACOLOGY

Systematic Review and Meta-Analysis of Multiple-Session Early Interventions Following Traumatic Events

(2009) Neil P. Roberts et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Influence of Stress Hormones on Fear Circuitry

(2009) Sarina M. Rodrigues et al.   Annual Review of Neuroscience

Post-traumatic stress disorder: evolutionary perspectives

(2009) Chris Cantor   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Relapse of Successfully Treated Anxiety and Fear: Theoretical Issues and Recommendations for Clinical Practice

(2009) Mark J. Boschen et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Delayed extinction attenuates conditioned fear renewal and spontaneous recovery in humans.

(2009) Nicole C. Huff et al.   BEHAVIORAL NEUROSCIENCE

New Findings on Extinction of Conditioned Fear Early in Development: Theoretical and Clinical Implications

(2009) Jee Hyun Kim et al.   BIOLOGICAL PSYCHIATRY

Spacing extinction trials alleviates renewal and spontaneous recovery

(2009) G. P. Urcelay et al.   LEARNING & BEHAVIOR

Early extinction after fear conditioning yields a context-independent and short-term suppression of conditional freezing in rats

(2009) C.-h. Chang et al.   LEARNING & MEMORY

Preventing the return of fear in humans using reconsolidation update mechanisms

(2009) Daniela Schiller et al.   NATURE

Beyond extinction: erasing human fear responses and preventing the return of fear

(2009) Merel Kindt et al.   NATURE NEUROSCIENCE

Chronic stress and sex differences on the recall of fear conditioning and extinction

(2009) Sarah E. Baran et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Estrous cycle phase and gonadal hormones influence conditioned fear extinction

(2009) M.R. Milad et al.   NEUROSCIENCE

Extinction-Reconsolidation Boundaries: Key to Persistent Attenuation of Fear Memories

(2009) M.-H. Monfils et al.   SCIENCE

Exercise is associated with reduction in the anxiogenic effect of mCPP on acoustic startle.

(2008) James H. Fox et al.   BEHAVIORAL NEUROSCIENCE

Voluntary exercise in C57 mice is anxiolytic across several measures of anxiety

(2008) J SALAM et al.   BEHAVIOURAL BRAIN RESEARCH

Pavlovian fear conditioning as a behavioral assay for hippocampus and amygdala function: cautions and caveats

(2008) Stephen Maren   EUROPEAN JOURNAL OF NEUROSCIENCE

Massed extinction trials produce better short-term but worse long-term loss of context conditioned fear responses than spaced trials.

(2008) Sophie H. Li et al.   JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL LEARNING AND COGNITION

Presence and acquired origin of reduced recall for fear extinction in PTSD: Results of a twin study

(2008) Mohammed R. Milad et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Switching on and off fear by distinct neuronal circuits

(2008) Cyril Herry et al.   NATURE

d-Cycloserine facilitates context-specific fear extinction learning

(2008) Mark E. Bouton et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Neural Circuitry Underlying the Regulation of Conditioned Fear and Its Relation to Extinction

(2008) Mauricio R. Delgado et al.   NEURON

Exposure to a stressor produces a long lasting enhancement of fear learning in rats

(2008) Vinuta Rau et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Effects of enrichment predominate over those of chronic stress on fear-related behavior in male rats

(2008) Rupshi Mitra et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS