Article
Polymer Science
Uttam C. Paul, Gozde Bayer, Silvia Grasselli, Annalisa Malchiodi, Ilker S. Bayer
Summary: Waterborne polyurethane dispersions can be used to produce environmentally friendly and biodegradable plastic films with good mechanical properties and transparency by hybridizing with polyvinylpyrrolidone.
Article
Biochemistry & Molecular Biology
Jutarat Prachayawarakorn, Pornthip Kansanthia
Summary: The poor properties of native cassava starch film can be improved through dual modification methods, such as hydrogen peroxide oxidation and glutaraldehyde crosslinking. This results in starch films with lower water uptake, better mechanical properties, stiffness, extensibility, and thermal properties. The sequential dual modification process also leads to enhanced performance in terms of swelling power, moisture absorption, and biodegradability.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Felipe Lopez-Saucedo, Leticia Buendia-Gonzalez, Hector Magana, Guadalupe Gabriel Flores-Rojas, Emilio Bucio
Summary: This study proposes the development of an affordable polymer film for healthcare purposes. The film consists of chitosan, itaconic acid, and Randia capitata fruit extract. The film is formed through crosslinking of chitosan with itaconic acid and in situ addition of R. capitata fruit extract. The resulting ionically crosslinked composite film shows promising potential as a wound dressing due to the combined properties of chitosan and R. capitata fruit extract in supporting epithelial regeneration.
Article
Chemistry, Physical
Ivana Mrsic, Anita Lorenz, Ralph J. Lehnert, Gunter Lorenz, Thomas Chasse
Summary: For medical polymers, the surface condition is crucial for biocompatibility, with the separation of Irganox antioxidant affecting the chemical composition and stability. Different polymers from the Pellethane series were examined for blooming, with techniques like SEM and Raman microscopy used for evaluation. The bloomed areas increased with film thickness and slightly impacted protein structures on the surface.
APPLIED SURFACE SCIENCE
(2022)
Article
Food Science & Technology
Nguyen Ngoc Thanh Tien, Hiep Thi Nguyen, Ngoc Lieu Le, Tran Tien Khoi, Aurore Richel
Summary: The goal of this study was to produce and evaluate biodegradable films using pectin from dragon fruit peel, potato starch, and glycerol. The films were crosslinked with glutaraldehyde solution and exhibited different properties compared to non-crosslinked films. Crosslinked films showed improved tensile strength, elongation at break, and reduced solubility, thickness, density, and water vapor permeability. The film made with pectin and annealed starch demonstrated the best properties and potential for food packaging applications.
FOOD PACKAGING AND SHELF LIFE
(2023)
Article
Polymer Science
Berna Ozturk, Tugce Inan, Husnu Atakul, Fatma Seniha Guner
Summary: This study develops a new formulation of polyurethane (PU) from partly renewable resources. PU composites were prepared with castor oil (CO), polyethylene glycol (PEG3000), and hexamethylene diisocyanate (HDI). Different amounts of magnetite or carbonyl iron were used as magnetic particles. Various hydrophilic/hydrophobic PU composites with different melting and glass transition temperatures were successfully prepared. A PU composite with good shape recovery ratio (Rr = 96.1%) in a magnetic field was obtained using 10% magnetite.
EXPRESS POLYMER LETTERS
(2023)
Article
Food Science & Technology
Zhengqi Liu, Zihao Qin, Hanxiao Jia, Jing Xu, Ming Liu, Zhaosheng Hou
Summary: This study developed a dual-crosslinking strategy for preparing high-starch content composites of starch-poly(ester urethane)-oligochitosan (SPEO). The SPEO composites exhibited enhanced mechanical properties and biodegradability due to the dual-crosslinking structures. The introduction of oligochitosan further improved the surface hydrophilicity and bacteriostatic activity of the composites. The high-starch content composites with superior performance have great potential as a substitute for petroleum-derived plastics in food packaging applications.
FOOD PACKAGING AND SHELF LIFE
(2023)
Article
Materials Science, Characterization & Testing
Beom-Gon Cho, Jung-Eun Lee, Seung-Yeol Jeon, Han Gi Chae
Summary: Polyacrylonitrile (PAN) films blended with shellac, a biodegradable polymer, were prepared by a simple solution casting method. The miscibility of PAN with shellac polymer was investigated, and the optimal concentration of shellac that resulted in hydrogen bonding between shellac and PAN chain was determined. The introduction of shellac segments facilitated the disruption of the crystalline structure of the PAN chain, leading to a lower oxidation temperature in the PAN/shellac blends film. The optimal PAN/shellac blends film exhibited superior mechanical properties compared to the control PAN film.
Article
Biochemistry & Molecular Biology
Kittichai Sornsumdaeng, Panpailin Seeharaj, Jutarat Prachayawarakorn
Summary: In this study, rice starch film was crosslinked with citric acid and modified with different contents of calcium oxide to improve its packaging applications. The combination of citric acid and calcium oxide resulted in decreased swelling and moisture uptake, increased stiffness, and enhanced antibacterial activity. The film added with 5 wt% calcium oxide showed the highest stiffness and antibacterial activity, demonstrating the potential for improved properties in packaging materials.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Elzbieta Czarnecka, Jacek Nowaczyk, Miroslawa Prochon, Anna Masek
Summary: This study focuses on the development of a superabsorbent polymer material that exhibits high fluid absorbance and biodegradability. The swelling and dehydration kinetics of hydrogels formed by grafting polymerization of carboxymethyl starch and chitosan were studied, and the surface morphology and texture properties of the hydrogels were observed using scanning electron microscopy. Spectroscopic analyses confirmed the formation of acetal crosslink bridges including vanillin molecules.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Shuai Chen, Jianglei Qin, Jianzhong Du
Summary: Polymer films are widely used in various applications such as biomaterials, electronic devices, food packaging, and gas separation membranes. This study successfully fabricated cross-linkable and biodegradable polymer films, which can be tuned by varying the cross-linking density.
ACTA PHYSICO-CHIMICA SINICA
(2022)
Article
Chemistry, Multidisciplinary
Dinesh Kumar Chelike, Senthil A. Gurusamy A. Thangavelu
Summary: A facile synthesis of isocyanate free polyurethanes (PU) was achieved by reacting biodegradable cyclic carbonate with sustainable diamines via chemical modification. The resulting PU films showed high onset degradation temperature and were further characterized and studied for various properties and behaviors.
Article
Nanoscience & Nanotechnology
Qunsong Wang, Xiaoye Yu, Xianmiao Chen, Jingming Gao, Daokun Shi, Yang Shen, Jingyu Tang, Junhao He, Anning Li, Lin Yu, Jiandong Ding
Summary: In this study, a biodegradable polymer-based radiopaque raw material was prepared by blending poly(L-lactic acid) and iohexol. The composite material exhibited radiopacity and biodegradability, which was confirmed by in vitro and in vivo experiments. The presence of solid particles significantly enhanced the crystallization of poly(L-lactic acid), which should be considered in the design of biomaterial composites.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Textiles
Ammar Mustafa Al-Areqi, Bandar Aloyaydi, Subbarayan Sivasankaran, Fahad A. Al-Mufadi
Summary: Composite materials were fabricated and tested, including a tri-material structure (TMS) with a 3D-printed PLA lattice frame infilled with PUFs reinforced with MGFs. Mechanical tests showed that TMS samples displayed enhanced mechanical behavior due to effective dispersion and load transfer ability. Helmet prototypes of TMS with different MGFs content were also compared, with the 3.75 vol% sample showing the most improved performance.
FIBERS AND POLYMERS
(2023)
Article
Green & Sustainable Science & Technology
Hyeonseo Joo, Sujeong Gwak, Mun Hwan Lee, Hyosik Park, Cheoljae Lee, Ju Hun Lee, Sang A. Han, Ju-Hyuck Lee
Summary: This study presents the design of a biodegradable TPU for the development of high-powered TENGs with controlled biodegradability. The modified TPU-based TENG exhibited significantly increased output performance, reaching a voltage of 74.03V and a current of 1.98 mu A. The maximum power density was increased by approximately 1423 times compared to the native TPU-based TENG.
SUSTAINABLE MATERIALS AND TECHNOLOGIES
(2023)
Article
Materials Science, Ceramics
Breno R. Barrioni, Sandhra M. de Carvalho, Parichart Naruphontjirakul, Elizabeth Norris, Nicole L. Kelly, John V. Hanna, Julian R. Jones, Marivalda de M. Pereira
Summary: Novel monodispersed spherical dense BGNPs with a diameter of 92 nm and cobalt as the pro-angiogenic ion were obtained using a modified Stober method. The controlled release of Co2+ ions in culture media indicated the great potential of these materials as intracellular ion delivery systems with therapeutic properties. The study confirmed the presence of Co2+ species and the role of Co and Ca as network modifiers in the silica glass through various analytical techniques.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2022)
Article
Microbiology
Alcides Almeida de Arruda, Joice Dias Correa, Youvika Singh, Sicilia Rezende Oliveira, Caio Cavalcante Machado, Ayda Henriques Schneider, Julliane Dutra Medeiros, Gabriel R. Fernandes, Soraia Macari, Breno Rocha Barrioni, Mariana de Souza Santos, Leticia Fernanda Duffles, Helder Takashi Imoto Nakaya, Sandra Yasuyo Fukada, Dana T. Graves, Fernando Queiroz Cunha, Tarcilia Aparecida Silva
Summary: This study investigates the impact of rheumatoid arthritis (RA) treatment on the oral and gut microbiome in a mouse model. The results suggest that RA induction alters the microbial communities in the oral and gut microbiome, while methotrexate (MTX) treatment restores microbial stability and improves related symptoms and periodontal bone health.
Article
Obstetrics & Gynecology
D. A. Galdino-Alves, G. J. de Sa Pereira, N. de Oliveira Bertolini, R. D. Ferreira, M. de Souza Santos, B. R. Barrioni, M. de Magalhaes Pereira, E. F. Andrade, B. Del Bianco-Borges, L. J. Pereira
Summary: This study evaluated the effects of resistance training combined with prebiotic beta-glucan on ovariectomized mice. The results showed that resistance training promoted bone health, while prebiotic beta-glucan ingestion did not provide additional benefits.
Article
Chemistry, Applied
Geanne Aparecida de Paula, Nubya Nascimento Costa, Thais Martins da Silva, Kamila Areas Bastos, Mariana Drummond Costa Ignacchiti, Juliana Aparecida Severi, Rodrigo Lambert Orefice, Lilian Gasparelli Carreira, Janaina Cecilia Oliveira Villanova, Juliana Alves Resende
Summary: Polymeric films containing pomegranate peel extract show promising potential as a drug-delivery platform for topical treatment of candidiasis, as they exhibit adequate mechanical properties and antifungal activity against various Candida species.
NATURAL PRODUCT RESEARCH
(2023)
Article
Materials Science, Ceramics
Marcelo da Silva Mantini Viana, Thalita Marcolan Valverde, Breno Rocha Barrioni, Alfredo Miranda de Goes, Marcos Augusto de Sa, Marivalda de Magalhaes Pereira
Summary: This study obtained cobalt-containing nanoparticles with the potential to release pro-angiogenic ions using a sol-gel based method, which can be applied for tissue repair and tissue engineering.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Multidisciplinary
Priscilla Mol Queiroz, Breno Rocha Barrioni, Jesus Nuncira, Marivalda de Magalhaes Pereira
Summary: Thermosensitive injectable hydrogels are studied as a minimally invasive tool for delivering therapeutic agents. In this study, a new hydrogel containing mesoporous bioactive glass nanoparticles was developed for bone tissue regeneration. The results showed that the hydrogel had suitable injectability and temperature stability, making it a potential injectable system for therapeutic agents release in situ.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Materials Science, Ceramics
Francisco B. Fantecelle, Diogo M. M. dos Santos, Breno R. Barrioni, Marivalda M. Pereira, Himad A. Alcamand, Miguel L. Laper, Manuel Houmard, Eduardo H. M. Nunes
Summary: This work focuses on the preparation of freeze-cast scaffolds using a bioactive glass from the SiO2-CaO-Na2O-P2O5-K2O-MgO system. The material could be sintered at lower temperatures, providing energy and cost savings. The scaffolds showed desirable mechanical stability and exhibited bioactivity by inducing hydroxyapatite formation.
CERAMICS INTERNATIONAL
(2023)
Article
Polymer Science
Diego Oliveira Miranda, Matheus Figueiredo Dorneles, Rodrigo Lambert Orefice
Summary: In this study, the idea of synthesizing conjugated polymers (polyaniline, PANI) within the core of a core-shell submicron electrospun fiber was tested. The shell of the fiber was prepared through photopolymerization during electrospinning, while the core was produced from an aniline-rich solution. Polymerization of aniline occurred during electrospinning, leading to the formation of highly doped and conductive emeraldine PANI. The ability of the fiber shell to swell in water and create materials with low elastic modulus, similar to hydrogels, was also observed.
POLYMER INTERNATIONAL
(2023)
Article
Cell Biology
Mariana Rates Gonzaga Santos, Ian de Meira Chaves, Celso Martins Queiroz-Junior, Allysson Thiago Cramer, Thales Augusto Anestino, Anna Clara Paiva Menezes dos Santos, Paulo Gaio Leite, Soraia Macari, Breno Rocha Barrioni, Marivalda de Magalhaes Pereira, Mauro Martins Teixeira, Danielle da Gloria de Souza, Mila Fernandes Moreira Madeira, Fabiana Simao Machado
Summary: This study investigated the role of SOCS2 in Aa-induced alveolar bone loss. Alveolar bone loss was induced by infecting mice with Aa and bone parameters, cell counts, and cytokine profile were evaluated. Results showed that SOCS2 deficiency increased alveolar bone loss despite decreased proinflammatory cytokine production. Therefore, SOCS2 is a regulator of Aa-induced bone loss and an important target for preventing alveolar bone loss in periodontal inflammatory conditions.
INFLAMMATION RESEARCH
(2023)
Article
Polymer Science
Monique Cotrim, Rodrigo Orefice
Summary: In recent years, the use of polycaprolactone/silk (PCL/S) blend micro/nanofibers for biomaterial applications has been explored due to their beneficial combination of biodegradability, biocompatibility, and bioactivity. However, the conventional form of these fibers (mats) has limited use due to poor mechanical properties. To overcome this issue, nanofiber yarns (NF-Ys) have been fabricated, combining the advantages of nanofibers with superior mechanical properties. This paper investigates the production of PCL/S NF-Ys by electrospinning and explores the effect of composition and processing parameters on the morphology, tensile properties, and processability of these nanofibers.
Article
Engineering, Biomedical
Joana Lobato Barbosa, Mariane Izabella Abreu de Melo, Pricila da Silva Cunha, Marcelo Coutinho de Miranda, Breno Rocha Barrioni, Cheisy Daiana Freitas Moreira, Andrea da Fonseca Ferreira, Rosa Maria Esteves Arantes, Marcos Augusto de Sa, Marivalda de Magalhaes Pereira, Michele Angela Rodrigues, Silviene Novikoff, Dawidson Assis Gomes, Alfredo Miranda de Goes
Summary: In this study, a new bilayer scaffold composed of a chitosan-gelatin membrane and a chitosan-polyhydroxybutyrate (PHB) porous matrix was synthesized and populated with human adipose-derived mesenchymal stem cells (hASCs) to be potentially used for wound dressing applications. The results demonstrate that this scaffold has the potential to promote tissue regeneration in wound healing studies.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2023)
Article
Cell Biology
Mariana de S. Santos, Virginia T. M. Lima, Breno R. Barrioni, Juliana P. Vago, Jose Alcides A. de Arruda, Pedro D. Prazeres, Flavio A. Amaral, Tarcilia A. Silva, Soraia Macari
Summary: This study investigated the role of PI3K gamma in tooth movement and bone remodeling. The results showed that the deficiency or inhibition of PI3K gamma can reduce bone resorption and improve bone quality by increasing osteoblasts and decreasing osteoclasts. The PI3K gamma/Akt axis plays a crucial role in bone remodeling.
JOURNAL OF CELLULAR PHYSIOLOGY
(2023)
Article
Polymer Science
Sarah Oliveira Lamas de Souza, Sergio Mendes de Oliveira, Catarina Paschoalini Lehman, Merces Coelho da Silva, Luciana Maria Silva, Rodrigo Lambert Orelice
Summary: Tumor organoids have great potential as a 3D in vitro system to model cancer. Gelatin hydrogels with different levels of methacrylation and with cellulose nanocrystals (NCC) or reduced graphene oxide (rGO) were prepared and used to encapsulate human colon carcinoma cells (RKO). Results showed that NCC provided higher mechanical stability to the hydrogels and that GelMA with higher crosslink densities and NCC had higher cell population.
POLIMEROS-CIENCIA E TECNOLOGIA
(2023)
Article
Dentistry, Oral Surgery & Medicine
Ian de Meira Chaves, Marina Campos Zicker, Alice de Oliveira Laranjeira, Ana Leticia Malheiros Silveira, Daniele Cristina de Aguiar, Breno Rocha Barrioni, Adaliene Versiani de Matos Ferreira, Mauro Martins Teixeira, Tarcilia Aparecida da Silva, Daniele da Gloria de Souza, Mila Fernandes Moreira Madeira
Summary: Obesity may induce changes in oral microbiota and neutrophil recruitment, which are associated with alveolar bone loss. These findings emphasize the association between obesity and periodontal diseases.
JOURNAL OF APPLIED ORAL SCIENCE
(2022)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
