Article
Geochemistry & Geophysics
Guoqing Zhou, Haotian Zhang, Chao Xu, Xiang Zhou, Zhexian Liu, Dawei Zhao, Jinchun Lin, Gongbei Wu
Summary: This article presents a real-time data acquisition system (RTDAQS) based on ADC+FPGA+ZYNQ architecture, which utilizes high-speed serializer-deserializer (SerDes) data transfer technology. The system has the characteristics of high sampling rates, high resolution, and high accuracy, making it suitable for bathymetric LiDAR measurements. Experimental results show that the system can achieve a sampling rate of 2 GS/s, a sampling resolution of 14 bits, and a sampling accuracy of 6 LSB, meeting the demands of high sampling rate, high accuracy data acquisition, and quick data transmission in practice, and can be applied to various devices.
IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING
(2023)
Article
Instruments & Instrumentation
Xin Yu, Haojie Xia, Weishi Li, Jin Zhang, Songtao Chang
Summary: In this study, we developed a new FPGA-based TDC that utilizes a carry-look-ahead delay chain structure, interleaved sampling method, and online calibration and bin readjustment approach. The TDC achieved high-resolution and high-precision time interval measurement.
REVIEW OF SCIENTIFIC INSTRUMENTS
(2022)
Article
Biology
Koji Yonekura, Saori Maki-Yonekura, Hisashi Naitow, Tasuku Hamaguchi, Kiyofumi Takaba
Summary: This study introduces a machine learning-based real-time object locator yoneoLocr, which can rapidly and accurately locate carbon holes and crystals, facilitating automated single particle analysis or cryo-electron crystallography data collection.
COMMUNICATIONS BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Jiajian Huang, Shengyao Ran, Wei Wei, Qun Yu
Summary: This paper presents a highly digitally integrated 2-D LiDAR system implemented in a low-cost FPGA. Utilizing the time-of-flight (ToF) method for ranging, the FPGA-TDC allows for flexibility of design and integration with more functional logics.
Article
Engineering, Biomedical
Sergio Pertuz Mendez, Marta Gherardini, Gabriel Vidigal de Paula Santos, Daniel M. Munoz, Helon Vicente Hultmann Ayala, Christian Cipriani
Summary: A new concept of human-machine interface for controlling hand prostheses using magnets implanted in residual muscles has been proposed. Machine learning models were employed to translate magnetic information to commands for prosthetic devices. The system achieved high tracking accuracy and low latency, with potential power efficiency compared to previous solutions.
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS
(2022)
Article
Chemistry, Analytical
Lilian R. Heil, Philip M. Remes, Jesse D. Canterbury, Ping Yip, William D. Barshop, Christine C. Wu, Michael J. MacCoss
Summary: Data-independent acquisition (DIA) mass spectrometry has become popular due to its reproducibility and quantitative rigor. However, traditional DIA methods may waste instrument time acquiring MS/MS spectra with no usable information. We developed a dynamic DIA strategy that improves quantification sensitivity without sacrificing the number of detected peptides.
ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Biomedical
Shirin Pourashraf, Andrea Gonzalez-Montoro, Jun Yeon Won, Min Sun Lee, Joshua W. Cates, Zhixiang Zhao, Jae Sung Lee, Craig S. Levin
Summary: A scalable detector readout design was developed for a 100 ps coincidence time resolution (CTR) time of flight (TOF) PET detector using 'fast-LGSO:Ce' scintillation crystals and SiPMs. Experimental results demonstrated a CTR of 102.03 +/- 1.9 ps achieved with single crystal elements and 113.4 +/- 0.7 ps with crystal arrays. The goal is to create the first TOF-PET system with 100 ps FWHM CTR using the presented readout architecture.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Chemistry, Analytical
Brandon Bills, William D. Barshop, Seema Sharma, Jesse Canterbury, Aaron M. Robitaille, Michael Goodwin, Michael W. Senko, Vlad Zabrouskov
Summary: Structural characterization of novel metabolites in drug discovery or metabolomics is challenging. We present a new LC/MS data acquisition strategy, Met-IQ, which automatically decides whether to perform an MSn acquisition based on the similarity between the experimental MS2 spectrum and a spectrum in a reference spectral library. This strategy significantly increases the MS2 instrument sampling rate and the number of MS2 spectra.
ANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Electrical & Electronic
Wassim Mansour, Rattana Biv, Cyril Ponchut, Raphael Ponsard, Nicolas Janvier, Pablo Fajardo
Summary: Scientific experiments rely on measurements to extract needed data, with data processing and analysis being essential components. Traditionally, detector development for photon sources focused on front-end performance, but now FPGA and GPU are used for complex tasks. This article introduces the implementation of real-time FPGA-based image manipulation techniques on the ESRF's data acquisition platform.
IEEE TRANSACTIONS ON NUCLEAR SCIENCE
(2021)
Article
Automation & Control Systems
Yu Wang, Wujun Xie, Haochang Chen, David Day-Uei Li
Summary: This article proposes a weighted histogram calibration method and an automatic calibration architecture to implement high-linearity TDCs in low-cost ARM-based SoCs. The proposed method significantly reduces the nonlinearity introduced by nonuniform bins. The implemented TDC offers good uniformity and resolution.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2022)
Article
Nuclear Science & Technology
Lingyun Ke, Junwei Yan, Jinda Chen, Changxin Wang, Xiuling Zhang, Chengming Du, Minchi Hu, Zuoqiao Yang, Jiapeng Xu, Yi Qian, Qianshun She, Haibo Yang, Hongyun Zhao, Tianlei Pu, Changxu Pei, Hong Su, Jie Kong
Summary: An algorithm for real-time digital time-stamp sorting used in In-Beam PET is presented. It efficiently identifies coincidence events in a large amount of data by sorting annihilation event data from front-end circuits. The algorithm has been verified to work under high event count rates and provides a design of electronic circuit with a small-scale structure.
NUCLEAR ENGINEERING AND TECHNOLOGY
(2021)
Article
Engineering, Multidisciplinary
Pawel Kwiatkowski, Dominik Sondej, Ryszard Szplet
Summary: This paper presents the design, operation, and test results of a novel integrated time interval counter that achieves exceptionally high resolution (0.4 ps) and precision (2.6 ps rms in the best case scenario). The counter operates based on the multisampling wave union (WU) method, utilizing both types of WU launchers, A and B, and implemented in Xilinx Kintex-7 FPGA device. Key factors contributing to the high performance of the counter include careful manual placement and routing of key components, as well as an efficient pre-encoder design to minimize bubble errors. Two approaches for implementing the pre-encoder in the FPGA chip, focused on logic resources saving or throughput enhancement (up to 385 MSa/s), were investigated. Thermal tests conducted in the range of 40 degrees C confirmed the temperature dependence of important parameters such as precision, resolution, and offset.
Article
Engineering, Electrical & Electronic
Shuaishuai Shen, Jing Zheng, Yuan Sun, Xingzhi Teng, Suping Peng
Summary: Surface microseismic monitoring is a critical technology for monitoring subsurface reservoir processes, but it faces challenges in weak signal acquisition and real-time data monitoring. This study presents a design approach using buried sensors and low-cost embedded devices to develop a microseismic monitoring data logger with acquisition, synchronization, record, and transmission functions. The system is evaluated for its monitoring abilities and noise level.
IEEE SENSORS JOURNAL
(2022)
Article
Chemistry, Analytical
Alessandro Cilardo
Summary: Efficient data movement in multi-node systems is crucial for demanding data acquisition applications, with this research evaluating the use of high-bandwidth interconnect standards and remote direct memory access functions in a prototype aiming to optimize FPGA accelerator memory utilization while supporting state-of-the-art interconnect technologies.
Article
Engineering, Electrical & Electronic
A. Malige, G. Korcyl, M. Firlej, T. Fiutowski, M. Idzik, B. Korzeniak, R. Lalik, A. Misiak, A. Molenda, J. Moron, N. Rathod, P. Salabura, J. Smyrski, K. Swientek, P. Wintz
Summary: Large-scale physics experiments with high interaction rates require high-performance data acquisition systems. The PANDA experiment at FAIR is an example that uses real-time feature extraction, filtering, and high-level correlations for event selection. A firmware framework has been developed for real-time data processing and tested with the PANDA Forward Tracker prototype.
IEEE TRANSACTIONS ON NUCLEAR SCIENCE
(2022)
Article
Engineering, Multidisciplinary
Frederic Vachon, Samuel Parent, Frederic Nolet, Henri Dautet, Jean-Francois Pratte, Serge A. Charlebois
Summary: The characterization of nuisance parameters in digital SiPMs using ZPP and TD methods enables the correct separation of correlated and uncorrelated events, allowing for the determination of true PDE.
MEASUREMENT SCIENCE AND TECHNOLOGY
(2021)
Article
Engineering, Biomedical
Emilie Gaudin, Christian Thibaudeau, Louis Arpin, Jean-Daniel Leroux, Maxime Toussaint, Jean-Francois Beaudoin, Jules Cadorette, Maxime Paille, Catherine M. Pepin, Konin Koua, Jonathan Bouchard, Nicolas Viscogliosi, Caroline Paulin, Rejean Fontaine, Roger Lecomte
Summary: LabPET II is a new PET technology platform designed for high-resolution imaging, achieving submillimetric spatial resolution in preclinical and clinical settings. Results show promising capabilities for biomolecular imaging in preclinical research, with submillimetric resolution achieved in hot spot phantoms and exceptional contrast for tiny bone structures in mice.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Review
Chemistry, Analytical
Jean-Francois Pratte, Frederic Nolet, Samuel Parent, Frederic Vachon, Nicolas Roy, Tommy Rossignol, Keven Deslandes, Henri Dautet, Rejean Fontaine, Serge A. Charlebois
Summary: Analog and digital SiPMs have revolutionized radiation instrumentation, but certain applications demand higher performance. 3D photon-to-digital converters show potential for superior performance and can be applied in various fields such as medical imaging and experimental research. Design choices for optimized 3D photon-to-digital converters for radiation instrumentation are discussed in detail.
Article
Engineering, Biomedical
Francis Loignon-Houle, Stefan Gundacker, Maxime Toussaint, Felix Camirand Lemyre, Etiennette Auffray, Rejean Fontaine, Serge A. Charlebois, Paul Lecoq, Roger Lecomte
Summary: The paper discusses the challenges in achieving 10 ps CTR in TOF-PET globally and presents the concept of time-based DOI estimation. Experimental measurements and simulation studies demonstrate the effectiveness of this concept in improving timing precision of detectors. This two-step approach provides insights into utilizing timing signal features for DOI estimation in order to achieve ultra-fast CTR while maintaining detection efficiency for TOF PET.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Engineering, Electrical & Electronic
William Lemaire, Maher Benhouria, Konin Koua, Marwan Besrour, Louis-Philippe Gauthier, Gabriel Martin-Hardy, Tommy Rossignol, Sebastien Roy, Rejean Fontaine
Summary: This article presents a retinal implant ASIC architecture optimized for optical operation despite constraints in vision restoration. The implant contains 288 individually controlled electrode drivers and features a digital controller with flexible stimulation sequences.
IEEE JOURNAL OF SOLID-STATE CIRCUITS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Nikta Zarif Yussefian, Maxime Toussaint, Emilie Gaudin, Roger Lecomte, Rejean Fontaine
Summary: This study explores the advantages of TOF scanners in improving image CNR, as well as the feasibility of improving timing performance and reducing scintillator material cost by decreasing crystal length. Results show that decreasing crystal length can improve CRC performance, while increasing scan time can fully recover CNR.
IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES
(2021)
Article
Instruments & Instrumentation
Francis Loignon-Houle, Serge A. Charlebois, Rejean Fontaine, Roger Lecomte
Summary: This study investigates the spatial, temporal, and energy evolution of primary electrons generated by 511 keV photons in different scintillators using Monte Carlo simulations. The simulation results show that the electron track is tortuous with a short extent and rapid energy transfer in high-Z or high density materials, while it is longer and less tortuous in lighter materials. These simulations provide insights into the dynamics of energy transfer in different detector concepts.
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Haithem Bouziri, Catherine M. Pepin, Konin Koua, Maher Benhouria, Caroline Paulin, Jinsong Ouyang, Marc Normandin, Jean-Francois Pratte, Georges El Fakhri, Roger Lecomte, Rejean Fontaine
Summary: A more robust crystal identification solution based on dual-threshold time-over-threshold (ToT) technique was proposed and tested in phoswich detectors with various scintillator combinations. The method demonstrated successful crystal identification with high accuracy in broad energy windows, showing potential for application in future detectors.
IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Nikta Zarif Yussefian, Emilie Gaudin, Roger Lecomte, Rejean Fontaine
Summary: This study investigates the method of improving lesion detectability in small animal PET by enhancing coincidence time resolution. The relationship between crystal length, TOF resolution, and CNR performance is derived through simulations, providing a predictive model with a mean-squared error of 0.69.
IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES
(2022)
Article
Engineering, Electrical & Electronic
Narjes Moghadam, Roger Lecomte, Rejean Fontaine
Summary: Carbon nanotube-based composites with polydimethylsiloxane (PDMS) as a matrix show promising properties in terms of electrical conductivity and electromagnetic interference shielding, effectively eliminating artifacts in PET/MRI scanners caused by low-frequency electromagnetic interferences.
MICROELECTRONIC ENGINEERING
(2022)
Article
Chemistry, Analytical
Simon Carrier, Michel Labrecque-Dias, Ramy Tannous, Pascal Gendron, Frederic Nolet, Nicolas Roy, Tommy Rossignol, Frederic Vachon, Samuel Parent, Thomas Jennewein, Serge Charlebois, Jean-Francois Pratte
Summary: We propose an integrated single-photon detection device designed specifically for time-bin encoded single photons in quantum key distribution (QKD). We have successfully implemented and demonstrated a prototype photon-to-digital converter (PDC) that combines an 8 x 8 single-photon avalanche diode (SPAD) array with on-chip digital signal processing in TSMC 65 nm CMOS. The PDC prototype achieves a timing resolution of 22.7 ps RMS and operates effectively in a time-bin setup at an optical wavelength of 410 nm. This PDC serves as a crucial component for QKD receivers and enables the development of compact and robust time-bin QKD systems with imaging detectors.
Article
Radiology, Nuclear Medicine & Medical Imaging
David Gaudreault, Julien Rossignol, Yves Berube-Lauziere, Rejean Fontaine
Summary: Computed tomography (CT) is commonly used in medical imaging to reconstruct 3-D images of patients, and recent research has focused on techniques like time-correlated single-photon counting (TCSPC) CT to reduce scatter contributions and improve image quality. Simulations show that TCSPC implementation can improve contrast-to-noise ratio, accuracy, and artifact levels in reconstructed images compared to other CT scanner implementations, by effectively reducing scatter contributions.
IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES
(2021)
Article
Materials Science, Biomaterials
Arman Ahnood, Ross Cheriton, Anne Bruneau, James A. Belcourt, Jean Pierre Ndabakuranye, William Lemaire, Rob Hilkes, Rejean Fontaine, John P. D. Cook, Karin Hinzer, Steven Prawer
ADVANCED BIOSYSTEMS
(2020)
Article
Materials Science, Multidisciplinary
Khatereh Edalati, Melanie Stamp, Kumaravelu Ganesan, Alastair Stacey, Gabriel Martin-Hardy, Rejean Fontaine, Steven Prawer, David J. Garrett
DIAMOND AND RELATED MATERIALS
(2020)
