Article
Engineering, Environmental
Na Chu, Qinjun Liang, Wen Hao, Yong Jiang, Peng Liang, Raymond Jianxiong Zeng
Summary: This paper reviews cutting-edge studies on strategies to create high performance microbial electrochemical biosensors, focusing on different sensing elements including bioanode and abiotic cathode elements. These sensors have been successfully applied in the laboratory to detect various toxicants, with recent advancements in biocathode sensing elements highlighted for their ability to solve issues of low sensitivity and high false-negative rates in water biotoxicity monitoring. Discussions on limitations and potential solutions associated with the practical application of microbial electrochemical sensors for water biotoxicity monitoring are also emphasized.
CHEMICAL ENGINEERING JOURNAL
(2021)
Review
Environmental Sciences
Fatemeh Karimi, Hassan Karimi-Maleh, Jalal Rouhi, Najmeh Zare, Ceren Karaman, Mehdi Baghayeri, Li Fu, Sadegh Rostamnia, Elena Niculina Dragoi, Ali Ayati, Pavel Krivoshapkin
Summary: Carbon-based electrochemical biosensors have the potential to revolutionize cancer monitoring by providing early detection, personalized treatment options, and treatment response tracking. This review paper examines the latest developments and possibilities of these sensors in cancer surveillance. It discusses the principles, qualities, and applicability of carbon-based electrochemical sensors in detecting cancer biomarkers, evaluating therapy responses, and detecting cancer recurrence early. Furthermore, it compares their performance measures with existing monitoring methods and upcoming technologies. The paper also highlights prospective tactics, future initiatives, and commercialization opportunities for improving the capabilities of these sensors and integrating them into normal clinical practice.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Kaiyu Fu, Ji-Won Seo, Vladimir Kesler, Nicolo Maganzini, Brandon D. Wilson, Michael Eisenstein, Boris Murmann, H. Tom Soh
Summary: This study successfully optimized electrochemical aptamer biosensors on nanoporous electrodes to improve sensitivity and proposed a novel mechanism. By tuning pore size, probe density, and electrochemical measurement parameters, it was experimentally verified that electron transfer is accelerated within nanostructured electrodes, leading to enhanced sensitivity.
Article
Electrochemistry
Yanju Wu, Zikang Li, Dongyang Han, Qunpeng Duan, Fei Wang
Summary: The study constructed an ErGO-CP6 composite film as a new electrochemical sensing platform for the determination of thiamethoxam using a pulsed potential method. The composite film demonstrated higher sensitivity and selectivity towards thiamethoxam compared to an ErGO film, with satisfactory results in recovery tests on cucumber and tomato samples. This promising electrochemical sensing platform offers rapid and sensitive analysis of thiamethoxam.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2021)
Review
Chemistry, Analytical
Oleh Smutok, Evgeny Katz
Summary: This review gives an overview of different biosensors, focusing on electrochemical analytical devices. It briefly explains the general approaches, construction, and performance of various biosensors. The article discusses how all the components of biosensors are brought together for analytical work, including the immobilization of biomolecular components and their integration with electronic devices. The review mainly covers general concepts of biosensing processes rather than specific modern achievements in the field.
Review
Materials Science, Multidisciplinary
Xiaoping Huang, Yufang Zhu, Ehsan Kianfar
Summary: A sensor is a tool that measures test compounds in a sample directly, with nanosensors specifically using nanostructures for detection. Biological sensors utilize biological elements for detection, while the simultaneous use of nanostructures and electrochemical techniques has led to the development of sensors with high sensitivity and decomposition capabilities.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Chemistry, Physical
Rafael N. P. Colombo, Graziela C. Sedenho, Frank N. Crespilho
Summary: Interest in developing and applying emerging biomaterials to sensing and energy devices' frameworks has grown significantly in recent years. The COVID-19 pandemic has prompted a need for reliable manufacturing and analysis, as well as low-cost detection methods. The challenge lies in the development of innovative materials and the design of biointerfaces for successful sensing objectives. At the same time, there is a global focus on the conception and application of biomaterials for eco-friendly energy generation, storage, and conversion.
CHEMISTRY OF MATERIALS
(2022)
Review
Chemistry, Analytical
Constanza J. Venegas, Soledad Bollo, Paulina Sierra-Rosales
Summary: This review provides a summary of the methods and results using carbon-based electrochemical (bio)sensors for detecting carbendazim in environmental and food samples. The focus is on the role of carbon nanotubes, carbon nitride, graphene, and its derivatives, and carbon-based materials as modifiers, along with the evaluation of analytical performance.
Article
Chemistry, Analytical
Michael Holzinger, Paulo Henrique M. Buzzetti, Serge Cosnier
Summary: Biosensors are crucial tools in the health and environmental sectors for fast and reliable diagnostics. Utilizing a combination of polymers and nanomaterials can enhance the performance of biosensors, potentially leading to more reliable health monitoring.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Materials Science, Multidisciplinary
Nuno F. Santos, Sonia O. Pereira, Ana Moreira, Ana V. Girao, Alexandre F. Carvalho, Antonio J. S. Fernandes, Florinda M. Costa
Summary: Laser-induced graphene (LIG) shows excellent electrochemical performance with high sensitivity to dopamine at physiologically relevant concentrations, and good selectivity. UV-induced LIG has advantages in sensor miniaturization.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Article
Chemistry, Physical
Sujin Kim, Dongryul Lee, Kyungmin Ahn, Jihyun Kim, Jungbae Kim
Summary: Remote SF6 plasma treatment is used to graft hydrophobic fluorine on the surface of CNTs, allowing for the adsorption of enzyme molecules. The loading of GOx on F-CNTs is correlated with plasma treatment time, with shorter treatment times leading to lower Rct values and increased sensitivity. Extending the treatment time results in increased resistance and sensitivity due to the dominance of covalently-attached fluorine.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Analytical
Xiao-Meng Ma, Jian-Wei Wang, Li-Ting Zhao, Yafei Zhang, Jun-Ying Liu, Songmei Wang, Daochen Zhu, Zhugen Yang, Yang-Chun Yong
Summary: A novel microfiber-like biohydrogel was developed using electroactive bacteria-induced graphene oxide reduction and confined self-assembly in a capillary tube. This biohydrogel enabled efficient electron exchange between cells and the conductive graphene network, and was used to create a miniature whole-cell electrochemical biosensing system for fumarate detection. The system exhibited high sensitivity and a low limit of detection, offering new possibilities for bioelectrochemical detection in small volumes or at high spatial resolutions.
ANALYTICAL CHEMISTRY
(2023)
Review
Biochemical Research Methods
Oren Bachar, Roy Cohen, Matan M. Meirovich, Yifat Cohen, Omer Yehezkeli
Summary: The advances in biotic-abiotic interfaced systems have great potential in bioanalytics and biocatalysis applications. The combination of nanoelements' unique electronic and optic properties with the selectivity and catalytic abilities of biotic materials can lead to superior features. These new nanobiohybrids may contribute to addressing global challenges such as alternative energy utilization and affordable biodiagnostics and therapeutics tools.
CURRENT OPINION IN BIOTECHNOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Anil Koklu, David Ohayon, Shofarul Wustoni, Victor Druet, Abdulelah Saleh, Sahika Inal
Summary: This review introduces the application of organic electronic materials in metabolite sensing, discusses the advantages and drawbacks of different detection strategies and technologies. At the same time, the state-of-the-art organic electronic metabolite sensors are classified, and the prospects and challenges of using organic bioelectronic materials for metabolite sensing are explored.
Review
Chemistry, Analytical
Jagannath Mondal, Jeong Man An, Sachin S. Surwase, Kushal Chakraborty, Sabuj Chandra Sutradhar, Joon Hwang, Jaewook Lee, Yong-Kyu Lee
Summary: The development of accurate diagnosis and monitoring of diseases has become more important after the COVID-19 pandemic. Carbon nanomaterials such as graphene and carbon nanotubes have been considered as important candidates for biosensing channels due to their excellent physical properties. Various sensing methods, including electrochemical, optical, and electrical approaches, have been used in carbon nanotube-based biosensing systems, showing excellent sensitivity and selectivity against viruses and virus DNA structures. These biosensing platforms have great potential in improving healthcare and public health.
Article
Pharmacology & Pharmacy
Alessandro Giuliani, Anna Giulia Balducci, Elisa Zironi, Gaia Colombo, Fabrizio Bortolotti, Luca Lorenzini, Viola Galligioni, Giampiero Pagliuca, Alessandra Scagliarini, Laura Calza, Fabio Sonvico
Article
Chemistry, Analytical
Vito A. Baldassarro, Alessandra Marchesini, Fabrizio Facchinetti, Gino Villetti, Laura Calza, Luciana Giardino
MICROCHEMICAL JOURNAL
(2018)
Article
Clinical Neurology
Alessandro Giuliani, Sandra Sivilia, Vito Antonio Baldassarro, Marco Gusciglio, Luca Lorenzini, Michele Sannia, Laura Calza, Luciana Giardino
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
(2019)
Article
Geriatrics & Gerontology
Daniela Beltrami, Gloria Gagliardi, Rema Rossini Favretti, Enrico Ghidoni, Fabio Tamburini, Laura Calza
FRONTIERS IN AGING NEUROSCIENCE
(2018)
Article
Veterinary Sciences
Chiara Bernardini, Martina Bertocchi, Augusta Zannoni, Roberta Salaroli, Irvin Tubon, Giovanni Dothel, Mercedes Fernandez, Maria Laura Bacci, Laura Calza, Monica Forni
BMC VETERINARY RESEARCH
(2019)
Article
Cell & Tissue Engineering
Vito Antonio Baldassarro, Wojciech Krezel, Mercedes Fernandez, Brigitte Schuhbaur, Luciana Giardino, Laura Calza
STEM CELL RESEARCH
(2019)
Article
Critical Care Medicine
Mercedes Fernandez, Vito Antonio Baldassarro, Rita Capirossi, Roberto Montevecchi, Jacopo Bonavita, Maura Cescatti, Tiziana Giovannini, Giulia Giovannini, Mariella Uneddu, Gordini Giovanni, Luciana Giardino, Laura Calza
JOURNAL OF NEUROTRAUMA
(2020)
Article
Cell Biology
N. Gostynska, M. Pannella, M. L. Rocco, L. Giardino, L. Aloe, L. Calza
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
(2020)
Article
Biotechnology & Applied Microbiology
Joseph Lovecchio, Micaela Pannella, Luciana Giardino, Laura Calza, Emanuele Giordano
BIOTECHNOLOGY AND BIOENGINEERING
(2020)
Article
Neurosciences
Vito Antonio Baldassarro, Alessandra Marchesini, Luciana Giardino, Laura Calza
Article
Immunology
Nozha Borjini, Sandra Sivilia, Alessandro Giuliani, Mercedes Fernandez, Luciana Giardino, Fabrizio Facchinetti, Laura Calza
JOURNAL OF NEUROINFLAMMATION
(2019)
Review
Biochemistry & Molecular Biology
Luca Lorenzini, Mercedes Fernandez, Vito Antonio Baldassarro, Andrea Bighinati, Alessandro Giuliani, Laura Calza, Luciana Giardino
Article
Computer Science, Artificial Intelligence
Flavio Bertini, Davide Allevi, Gianluca Lutero, Laura Calza, Danilo Montesi
Summary: Alzheimer's disease is the main form of dementia worldwide, with current pharmacological treatments only able to alleviate symptoms rather than halt the degenerative process. Research suggests that speech changes may be an early indication of cognitive defects, and an automated method using speech features has been proposed for classifying Alzheimer's disease patients.
COMPUTER SPEECH AND LANGUAGE
(2022)
Article
Cell Biology
Agnese Stanzani, Anna Sansone, Cinzia Brenna, Vito Antonio Baldassarro, Giuseppe Alastra, Luca Lorenzini, Chryssostomos Chatgilialoglu, Ilaria Laface, Carla Ferreri, Luca Maria Neri, Laura Calza
Summary: The study analyzed changes in lipid composition due to inflammatory conditions. The fatty acid composition was measured in erythrocytes and spinal cord tissue of mice affected by experimental allergic encephalomyelitis (EAE). The results showed a decrease in PUFAs and an increase in SFAs in the membrane during the acute phase of EAE, while PUFAs decreased in the spinal cord tissue.
Article
Cell Biology
Marzia Moretti, Riccardo Caraffi, Luca Lorenzini, Ilaria Ottonelli, Michele Sannia, Giuseppe Alastra, Vito Antonio Baldassarro, Alessandro Giuliani, Jason Thomas Duskey, Maura Cescatti, Barbara Ruozi, Luigi Aloe, Maria Angela Vandelli, Luciana Giardino, Giovanni Tosi, Laura Calza
Summary: Spinal cord injury (SCI) causes sensory and motor disabilities without any cure. To improve myelin repair and limit degeneration, a multitherapy using nanomedicines loaded with T3, ibuprofen, and mNGF was developed. In vitro experiments confirmed the efficacy of T3-NMeds in promoting oligodendrocyte precursor cell differentiation. In vivo rat experiments showed short-term anti-inflammatory effects and long-term improvements in myelination, suggesting the potential effectiveness of this multiple treatment for SCIs.