期刊
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES
卷 56, 期 12, 页码 3200-3208出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMTT.2008.2007338
关键词
Biological system modeling; biomedical applications of EM radiation; biomedical telemetry; implantable biomedical devices
We report live animal studies that verify and quantify successful transocular transmission of data from a miniature low-power implant. To minimize damage, implantation within layers of the eye requires an ultrasmall device on a scale of just a few millimeters on each side and less than 500 pro in thickness. A high-frequency transmitter integrated circuit (IC) was designed, fabricated, and bonded onto a board containing an antenna, matching network components, and interconnects. The transmitter must achieve sufficient efficiency to draw minimal power from the limited onboard storage array while outputting a sufficiently large signal to overcome tissue-induced attenuation. Two different versions of the system were developed, one using a low-temperature co-fired ceramic material for the substrate and the other using silicon. Animal studies performed using live rabbits followed by empirical measurements verified the feasibility of a wireless telemetry scheme for a low-power miniature ocular implant.
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