Article
Chemistry, Analytical
Jing Xu, Graham S. Wood, Enrico Mastropaolo, Peter Lomax, Michael Newton, Rebecca Cheung
Summary: A graphene/poly(methyl methacrylate) (PMMA) closed cavity resonator with a resonant frequency at around 160 kHz has been fabricated. The resonator has been actuated by mechanical, electrostatic, and electro-thermal methods, showing potential for acoustic sensing applications. The (1,1) mode dominates the resonance, indicating the effective clamping and sealing of the graphene/PMMA membrane. The resonant frequency can be tuned by applying an AC voltage through the membrane.
Article
Nanoscience & Nanotechnology
Lalit Chudal, Julien Santelli, Jacques Lux, Adam Woodward, Nazia Hafeez, Connor Endsley, Shea Garland, Robert F. Mattrey, Caroline de Gracia Lux
Summary: Activating patients' immune cells has revolutionized treatment, especially against cancer. Our study demonstrates the survival and function of macrophages loaded with low boiling point perfluorocarbon nanodroplets. These nanodroplet-loaded macrophages can be tracked and detected using a clinical ultrasound scanner, providing potential therapeutic strategies in the clinical setting.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Lalit Chudal, Julien Santelli, Jacques Lux, Adam Woodward, Nazia Hafeez, Connor Endsley, Shea Garland, Robert F. Mattrey, Caroline de Gracia Lux
Summary: Activating immune cells either by reengineering or bioactive molecules has revolutionized treatment, especially against cancer. Macrophages loaded with extremely low boiling point nanodroplets can survive ultrasound-induced phase change and maintain their function. In vivo detection of these labeled macrophages using a clinical ultrasound scanner represents a paradigm shift in cell tracking and potential therapeutic strategies.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Justin Ivancic, Gamani Karunasiri, Fabio Alves
Summary: This study reports on the design, modeling, analysis, and evaluation of a micro-electromechanical systems acoustic sensor and the novel design of an acoustic vector sensor array (AVS). The sensor demonstrated high acoustic sensitivity and signal-to-noise ratio, while the AVS showed accurate acoustic direction of arrival during field experiments. The results suggest the potential usefulness of this sensor and AVS design for specific applications.
Article
Engineering, Electrical & Electronic
Jackson Anderson, Yanbo He, Bichoy Bahr, Dana Weinstein
Summary: This study reports on the fabrication of unreleased acoustic resonators in 14 nm fin field-effect transistor technology. The resonators operate in the X-band frequency range and utilize phononic waveguides for acoustic confinement and metal-oxide-semiconductor devices for electromechanical driving and sensing of acoustic vibrations. The feasibility of integrating acoustic devices into standard complementary metal-oxide-semiconductor processes is demonstrated.
NATURE ELECTRONICS
(2022)
Article
Computer Science, Information Systems
Haiming Cheng, Wei Lou
Summary: Device-free acoustic sensing techniques have improved human-computer interaction for mobile devices of all sizes in various applications. Recent advancements have explored sound signals in different ways to achieve accurate and efficient tracking and recognition. However, most approaches are limited by sampling rate and bandwidth, leading to restrictions in applications. To overcome these limitations, we propose PD-FMCW, an ultrasound-based device-free tracking scheme that improves sensing resolution to submillimeter level. Evaluation results show that PD-FMCW achieves high accuracies in distance change, path length change, and trajectory tracking error, and is capable of recognizing micro-movements as small as 2 mm.
IEEE TRANSACTIONS ON MOBILE COMPUTING
(2023)
Article
Biology
Lia R. Gilmour, Marc W. Holderied, Simon P. C. Pickering, Gareth Jones
Summary: The study demonstrates that acoustic deterrents can effectively reduce human impacts on bats by causing bats to fly more directly, reducing flight tortuosity, and altering echolocation call structure in response to deterrent sound.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2021)
Article
Engineering, Manufacturing
Gergely Hantos, Marc P. Y. Desmulliez
Summary: This article investigates the root causes of failures affecting the low-frequency response of MEMS microphones and proposes methods to induce these failures. The information obtained from the frequency response of the devices is insufficient to separate the root causes of failures, but additional information about the circumstances regarding the onset of defects is sufficient for root cause identification.
IEEE TRANSACTIONS ON SEMICONDUCTOR MANUFACTURING
(2021)
Article
Chemistry, Analytical
Benedict Scheiner, Florian Probst, Fabian Michler, Robert Weigel, Alexander Koelpin, Fabian Lurz
Summary: As automation and predictive maintenance become increasingly important in industrial processes, acquiring as much data as possible is essential. However, the need for remote sensing in scenarios where moving parts may cause cable wear or harsh environments prevent wired connections poses challenges. Resonant surface acoustic wave (SAW) sensors offer the possibility of wireless interrogation, but current frequency reader systems have drawbacks that hinder widespread usage.
Article
Chemistry, Analytical
Eyglis Ledesma, Ivan Zamora, Arantxa Uranga, Francesc Torres, Nuria Barniol
Summary: This paper presents guidelines for optimizing piezoelectrical micromachined ultrasound transducers (PMUTs) monolithically integrated over a CMOS technology. It demonstrates that the buckled structure caused by residual stress in thin layers can be beneficial for enhancing performance of PMUTs, as shown through experimental and FEM studies. The fabricated PMUTs exhibit improved performance as both transmitters and receivers compared to previous devices using the same technology and state-of-the-art devices.
Article
Chemistry, Multidisciplinary
Laiming Jiang, Gengxi Lu, Yang Yang, Yang Xu, Fangjie Qi, Jiapu Li, Benpeng Zhu, Yong Chen
Summary: This study presents a multichannel piezo-ultrasound implant that integrates a hybrid waterborne acoustic metastructure, multiple piezo-harvesters, and a miniaturized circuit for selective wireless control via ultrasound frequency switching. The developed implant demonstrates potential for multifunctional operations and enhances ultrasound energy transfer versatility.
ADVANCED MATERIALS
(2021)
Article
Automation & Control Systems
Heng Wang, Shuda Dong, Qi Yang, Jiancheng Han, Ze'an He, Yihua He, Shuangyi Wang
Summary: In this article, a compact, inexpensive, and interactive ultrasonography simulator is developed using magnetic-inertial 6-DoF probe pose tracking and virtual ultrasound image generation. The simulator provides intuitive and interactive training experience for novice practitioners to acquire operation skills quickly.
IEEE-ASME TRANSACTIONS ON MECHATRONICS
(2023)
Review
Chemistry, Analytical
Norma Mallegni, Giovanna Molinari, Claudio Ricci, Andrea Lazzeri, Davide La Rosa, Antonino Crivello, Mario Milazzo
Summary: Acoustic signals play a crucial role in monitoring physiological and pathological conditions, and MEMS devices offer improved detection of their features. This article reviews the emerging applications of MEMS in healthcare, discussing the advantages and limitations of each framework. It also addresses the open questions and challenges that the scientific community must address in the near future.
Article
Engineering, Biomedical
Parth Chansoria, Suleman Asif, Nithin Gupta, Jorge Piedrahita, Rohan A. Shirwaiker
Summary: This study demonstrates a highly versatile ultrasound-assisted biofabrication (UAB) approach that utilizes radiation forces to rapidly organize cells and biomaterial additives within hydrogel constructs. The UAB approach is used with a hybrid bioink system to fabricate cartilaginous tissue constructs with enhanced mechanical properties and aligned cell morphology and collagen II secretion. The UAB approach is also combined with extrusion and stereolithography printing to fabricate constructs with 3D perfusable channels and organized cell and bioadditive patterns.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Physics, Fluids & Plasmas
A. Caumont, O. Stephan, E. Bossy, B. Dollet, C. Quilliet, P. Marmottant
Summary: Gas bubbles stabilized in toroidal 3D-printed cages exhibit unusual topology and serve as good acoustic resonators. Organizing them in a circular array forms an acoustic tokamak due to its torus shape. Experimentally and theoretically, it is shown that the system has multiple acoustic modes resulting from the acoustic interaction between tori. The fundamental acoustic mode has a significantly lower frequency than that of individual bubbles, and the acoustic field inside the acoustic tokamak is remarkably homogeneous according to our 3D simulations.
Article
Nanoscience & Nanotechnology
Roberto Bernasconi, Davide Carniani, Min-Soo Kim, Salvador Pane, Luca Magagnin
Summary: This paper describes the realization of artificial water striders using an inkjet-assisted electroforming approach. The striders are propelled by externally applied magnetic fields, and they show good maneuverability at different fluid interfaces. The research is significant for the development of microdevices capable of navigating various liquid environments.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Engineering, Electrical & Electronic
Cedric Fischer, Thomas Quirin, Christophe Chautems, Quentin Boehler, Joris Pascal, Bradley J. Nelson
Summary: Remote magnetic navigation (RMN) allows for precise and accurate wireless steering of magnetic catheters through complex structures. This study proposes a localization method that uses multiple Hall sensors to measure the magnetic fields produced by the magnetic navigation systems (MNSs) and estimate the full sensor pose. The results provide insights into the minimal requirements for an MNS in terms of localization accuracy.
IEEE TRANSACTIONS ON MAGNETICS
(2023)
Correction
Thermodynamics
Aysegul Demir Dilsiz, Kaitlynn Ng, Jerome Kampf, Zoltan Nagy
BUILDING SIMULATION
(2023)
Article
Chemistry, Multidisciplinary
Hao Ye, Kaiyuan Wang, Jian Zhao, Qi Lu, Menglin Wang, Bingjun Sun, Yang Shen, Hongchen Liu, Salvador Pane, Xiang-Zhong Chen, Zhonggui He, Jin Sun
Summary: The use of Golgi apparatus-Pd-l1 (-/-) exosome hybrid membrane coated nanoparticles (GENPs) can significantly reduce the secretion of PD-L1, leading to reduced tumor relapse rates. GENPs accumulate in tumors and disrupt PD-L1 production and exosome release through induction of intracellular events. Furthermore, they can mimic exosomes to activate T cells and promote systemic immune responses.
Review
Chemistry, Multidisciplinary
Min-Soo Kim, Jae-Kyung Heo, Hugo Rodrigue, Hyun-Taek Lee, Salvador Pane, Min-Woo Han, Sung-Hoon Ahn
Summary: Shape memory alloys (SMAs) are smart materials with high energy density, actuation strain, and biocompatibility characteristics, which are widely used in intelligent devices. This article summarizes the state-of-the-art thermal and magnetic SMA actuators, including their constituent materials, form, scaling effects, surface treatments, and functionalities. The motion performance of various SMA architectures is also analyzed. Current challenges and suggestions for advancing SMAs by considering material, form, and scale effects are emphasized.
ADVANCED MATERIALS
(2023)
Article
Robotics
Quentin Boehler, Simone Gervasoni, Samuel L. Charreyron, Christophe Chautems, Bradley J. Nelson
Summary: This article discusses the use of magnetic navigation systems in remote magnetic navigation to steer magnetic objects. The design, workspace definition, measurement methodology, and evaluation metrics of these systems are explored and illustrated with examples.
IEEE TRANSACTIONS ON ROBOTICS
(2023)
Article
Chemistry, Physical
Joao Pedro Vale, Abderrahime Sekkat, Thomas Gheorghin, Semih Sevim, Eirini Mavromanolaki, Andreas D. Flouris, Salvador Pane, David Munoz-Rojas, Josep Puigmarti-Luis, Tiago Sotto Mayor
Summary: Spatial atomic layer deposition (SALD) is a thin-film deposition technique that allows precise control over film growth without the need for vacuum. Through numerical simulation, design maps and a predictive equation were developed to predict the growth regime of SALD systems under different conditions. This provides researchers with a convenient way to design, operate, and optimize SALD systems.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Chemistry, Multidisciplinary
Junhee Choi, Dong-In Kim, Jin-Young Kim, Salvador Pane, Bradley J. Nelson, Young-Tae Chang, Hongsoo Choi
Summary: This study investigated the enhancement of intracellular uptake of superparamagnetic iron oxide nanoparticles (SPIONs) through the use of rotating magnetic fields (RMFs). The physical parameters for favorable chain length for intracellular uptake were predicted and validated. The study also showed that enhanced intracellular uptake reduced magnetic hyperthermia time and strength, as well as particle concentration.
Review
Chemistry, Multidisciplinary
Ehsan Rahimi, Roger Sanchis-Gual, Xiangzhong Chen, Amin Imani, Yaiza Gonzalez-Garcia, Edouard Asselin, Arjan Mol, Lorenzo Fedrizzi, Salvador Pane, Maria Lekka
Summary: The emergence of micro- and nanoswimmers (MNSs) in the past two decades has led to extensive research in engineering motile micro- and nanodevices for minimally invasive medicine. However, the degradation of MNSs in human physiological media is often overlooked. This review summarizes recent studies on the corrosion and biodegradation of MNSs, with a focus on metal-based devices, as well as strategies to enhance their stability.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Energy & Fuels
Kingsley Nweye, Siva Sankaranarayanan, Zoltan Nagy
Summary: Building and power generation decarbonization pose challenges to electric grid reliability. Grid-interactive efficient buildings can provide grid flexibility services through demand response. Reinforcement learning is suitable for energy management in such buildings, but its adoption is hindered by sample inefficiency, control security, and generalizability. In this study, we propose the MERLIN framework to address these challenges and demonstrate its effectiveness using real-world data.
Review
Energy & Fuels
Han Li, Hicham Johra, Flavia de Andrade Pereira, Tianzhen Hong, Jerome Le Dreau, Anthony Maturo, Mingjun Wei, Yapan Liu, Ali Saberi-Derakhtenjani, Zoltan Nagy, Anna Marszal-Pomianowska, Donal Finn, Shohei Miyata, Kathryn Kaspar, Kingsley Nweye, Zheng O'Neill, Fabiano Pallonetto, Bing Dong
Summary: Energy flexibility is important for balancing the fluctuating supply and demand in energy grids. This paper provides a review of data-driven energy flexibility key performance indicators (KPIs) for buildings and open datasets for testing these KPIs. The review identifies 48 KPIs from recent publications and evaluates 16 datasets suitable for demand response or building-to-grid services. Future opportunities include developing new methodologies, baseline-free KPIs, promoting standardization, and curating datasets for energy flexibility assessment.
Article
Pharmacology & Pharmacy
Kirstin Meiners, Prisca Hamm, Marcus Gutmann, Jan Niedens, Agnieszka Nowak-Krol, Salvador Pane, Tessa Luehmann
Summary: The study developed three polyethylene glycol (PEG)ylated tPA bioconjugates based on the recombinant human tPA drug Alteplase using site-specific conjugation strategies. These bioconjugates showed improved proteolytic activity, slower inhibition kinetics by PAI-1, and increased hydrodynamic size.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2023)
Proceedings Paper
Automation & Control Systems
Truong X. Nghiem, Jan Drgona, Colin Jones, Zoltan Nagy, Roland Schwan, Biswadip Dey, Ankush Chakrabarty, Stefano Di Cairano, Joel A. Paulson, Andrea Carron, Melanie N. Zeilinger, Wenceslao Shaw Cortez, Draguna L. Vrabie
Summary: Physics-informed machine learning (PIML) is a set of methods and tools that integrate machine learning algorithms with physical constraints and mathematical models developed in scientific and engineering domains. By incorporating physical laws and constraints, PIML models can be more effective and data-efficient compared to purely data-driven methods. This paper provides an overview of recent advances in PIML for dynamical system modeling and control, covering topics such as system identification, control, analysis, and digital twins.
2023 AMERICAN CONTROL CONFERENCE, ACC
(2023)
Article
Plant Sciences
Peter Erzberger, Janos Csiky, Kornel Barath, Abel Beranek, Judit Deme, Gabriella Fintha, Gusztav Jakab, Gabor Matus, Attila Mesterhazy, Jozsef Nagy, Zoltan Nagy, Csaba Nemeth, Tamas Pocs, David Schmidt, Andras Schmotzer, Peter Szucs, Matyas Wolf, Beata Papp
Summary: This study presents preliminary findings on the current frequency and geographical distribution of bryophytes in Hungary, revealing a total of 698 taxa. The results indicate a positive correlation between elevational range and surveyed area with bryophyte richness, while arable land cover showed a negative correlation.
JOURNAL OF BRYOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Joaquin Llacer-Wintle, Jan Renz, Lukas Hertle, Andrea Veciana, Denis von Arx, Jiang Wu, Pere Bruna, Marija Vukomanovic, Josep Puigmarti-Luis, Bradley J. Nelson, Xiang-Zhong Chen, Salvador Pane
Summary: Magnetoelectricity allows solid-state materials to generate electricity under magnetic fields. A new magnetopyroelectric (MPE) effect is demonstrated in nanostructured composites of magnetic and pyroelectric materials. The composites consist of magnetic iron oxide nanoparticles dispersed in a ferroelectric poly(vinylidene fluoride-trifluoroethylene) (P(VDF-TrFE)) matrix. This new approach provides an opportunity to develop magnetoelectric materials for various applications.
MATERIALS HORIZONS
(2023)
