The Prognostic Significance of Histone Lysine Demethylase JMJD3/KDM6B in Colorectal Cancer

Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα

(2014) Keisuke Yamamoto et al.   CARCINOGENESIS

VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2-Targeted Therapy

(2014) E. Riquelme et al.   CLINICAL CANCER RESEARCH

The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulated

(2014) Yasunao F Kamikawa et al.   Epigenetics

Histone demethylase Jumonji D3 (JMJD3/KDM6B) at the nexus of epigenetic regulation of inflammation and the aging process

(2014) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Enhancer of Zeste Homolog 2 (EZH2) Promotes Progression of Cholangiocarcinoma Cells by Regulating Cell Cycle and Apoptosis

(2013) Shigeki Nakagawa et al.   ANNALS OF SURGICAL ONCOLOGY

Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge

(2013) Jose Antonio Gomez-Sanchez et al.   BRAIN

Jmjd3 Inhibits Reprogramming by Upregulating Expression of INK4a/Arf and Targeting PHF20 for Ubiquitination

(2013) Wei Zhao et al.   CELL

Statins inhibit tumor progressionviaan enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer

(2013) S. Ishikawa et al.   INTERNATIONAL JOURNAL OF CANCER

Identification of miR-30e* Regulation of Bmi1 Expression Mediated by Tumor-Associated Macrophages in Gastrointestinal Cancer

(2013) Hidetaka Sugihara et al.   PLoS One

Expression and significance of histone H3K27 demethylases in renal cell carcinoma

(2012) Yongqing Shen et al.   BMC CANCER

Vitamin D has wide regulatory effects on histone demethylase genes

(2012) Fábio Pereira et al.   CELL CYCLE

The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation

(2012) S. Chen et al.   GENES & DEVELOPMENT

EZH2 Methyltransferase and H3K27 Methylation in Breast Cancer

(2012) Kyung Hyun Yoo et al.   International Journal of Biological Sciences

Histone Demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Protein Nuclear Stabilization

(2012) Chibawanye I. Ene et al.   PLoS One

Carcinogenesis of Intraductal Papillary Mucinous Neoplasm of the Pancreas: Loss of MicroRNA-101 Promotes Overexpression of Histone Methyltransferase EZH2

(2011) Osamu Nakahara et al.   ANNALS OF SURGICAL ONCOLOGY

Regulatory Mechanisms of Tumor Suppressor P16INK4Aand Their Relevance to Cancer

(2011) Junan Li et al.   BIOCHEMISTRY

The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway

(2011) P. Martinelli et al.   BLOOD

Aberrations of EZH2 in Cancer

(2011) A. Chase et al.   CLINICAL CANCER RESEARCH

H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic geneBCL2determines ERα ligand dependency

(2011) Amy Svotelis et al.   EMBO JOURNAL

KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells

(2011) Fábio Pereira et al.   HUMAN MOLECULAR GENETICS

Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes

(2011) Sookil Tae et al.   NUCLEIC ACIDS RESEARCH

Epigenetic regulation of theINK4b-ARF-INK4alocus

(2010) Nikolay Popov et al.   Epigenetics

Randomized Phase III Study of Panitumumab With Fluorouracil, Leucovorin, and Irinotecan (FOLFIRI) Compared With FOLFIRI Alone As Second-Line Treatment in Patients With Metastatic Colorectal Cancer

(2010) Marc Peeters et al.   JOURNAL OF CLINICAL ONCOLOGY

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis

(2009) Ø Fluge et al.   BRITISH JOURNAL OF CANCER

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

(2009) K. Agger et al.   GENES & DEVELOPMENT

Bevacizumab in Combination With Oxaliplatin-Based Chemotherapy As First-Line Therapy in Metastatic Colorectal Cancer: A Randomized Phase III Study

(2008) Leonard B. Saltz et al.   JOURNAL OF CLINICAL ONCOLOGY