Article
Multidisciplinary Sciences
Christoph Praschl, Lydia M. Zopf, Emma Kiemeyer, Ines Langthallner, Daniel Ritzberger, Adrian Slowak, Martin Weigl, Valentin Blueml, Nebojsa Nesic, Milos Stojmenovic, Kathrin M. Kniewallner, Ludwig Aigner, Stephan Winkler, Andreas Walter
Summary: This paper presents a shallow three-dimensional U-Net architecture for vessel segmentation in mouse brains, which can detect blood vessels faster and more reliably compared to state-of-the-art vesselness filters. The model is open-source, can be achieved with a small dataset, and requires only a small subset of labelled training data. The average Dice score of the best setup in the cross-validation evaluation is 61.34%.
Article
Acoustics
Shanshan Tang, Hengwu Huang, Ping Gong, U-wai Lok, Chenyun Zhou, Lulu Yang, Kate M. Knoll, Kathryn A. Robinson, Shannon P. Sheedy, Joel G. Fletcher, David H. Bruining, John M. Knudsen, Shigao Chen
Summary: Vasculature assessment is critical for disease diagnosis and staging. This study presents an improved ultrasound microvessel imaging technique along with an adaptive vessel segmentation workflow for robust vessel identification and feature quantification.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2022)
Article
Clinical Neurology
Jorge A. Roa, Mario Zanaty, Carlos Osorno-Cruz, Daizo Ishii, Girish Bathla, Santiago Ortega-Gutierrez, David M. Hasan, Edgar A. Samaniego
Summary: This study compared different methods for quantifying wall enhancement of UIAs and determined the sensitivity and specificity of each method as a surrogate of aneurysm instability. The study found that CRstalk using maximal SI values was the most reliable objective method to quantify enhancement of UIAs on HR-VWI. There was a good correlation between different manufacturers and scans obtained using magnets of different strengths.
JOURNAL OF NEUROSURGERY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shanmukha Srinivas, Tara Retson, Aaron Simon, Jona Hattangadi-Gluth, Albert Hsiao, Nikdokht Farid
Summary: Stereotactic radiosurgery (SRS) is an effective treatment for cerebral arteriovenous malformations (AVMs), with early hemodynamic changes potentially detectable using four-dimensional (4D) flow MRI. This study found that after SRS, arterial flow decreased, draining vein flow and circumference decreased, and AVM volume decreased. These changes in hemodynamics may be detected earlier and more prominently with 4D flow than with standard MRI/MRA.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Clinical Neurology
Sebastien Soize, Pierre-Francois Manceau, Maxime Gauberti, Thibault Herbin, Mathieu Zuber, Laurent Pierot, Emmanuel Touze
Summary: This study found that in acute ischemic stroke, the presence of the susceptibility vessel sign (SVS) is related to the time from symptom onset. The probability of being SVS+ increased with time from symptom onset, with around 90% of patients showing SVS at 8 hours after symptom onset.
Article
Computer Science, Interdisciplinary Applications
Thomas Hadler, Clemens Ammann, Jens Wetzl, Darian Viezzer, Jan Groeschel, Maximilian Fenski, Endri Abazi, Steffen Lange, Anja Hennemuth, Jeanette Schulz-Menger
Summary: This study developed software called Lazy Luna for the quantitative evaluation of cardiovascular magnetic resonance imaging. The software allows for comparing annotated images from artificial intelligence and clinicians, ensuring accurate metric calculations. It provides a graphical user interface for non-programmers and enables the tracing of differences in segmentation results among readers to identify the origins of these differences. The software can be extended to new application cases.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jakob Koefoed Tingsgaard, Martin Heyn Sorensen, Annemie Stege Bojer, Robert H. H. Anderson, David Andrew Broadbent, Sven Plein, Peter Gaede, Per Lav Madsen
Summary: This study aimed to compare myocardial blood flow (MBF) determined from coronary sinus blood flow (MBFCS) with that determined from dynamic contrast-enhanced imaging (MBFDCE) in a large cohort. The results showed that MBFCS had good repeatability but had a certain bias and relatively large limits of agreement compared to MBFDCE.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hanyue Zhou, Jiayu Xiao, Siddarth Ganesh, Alexander Lerner, Dan Ruan, Zhaoyang Fan
Summary: An automated processing pipeline for quantitative plaque assessment based on 3D magnetic resonance vessel wall imaging (VWI) has been developed and evaluated. The VWI-APP was found to be an accurate and efficient approach for intracranial atherosclerotic plaque quantification.
Article
Cardiac & Cardiovascular Systems
Jason M. Tarkin, Deepa Gopalan
Summary: Multimodality cardiovascular imaging plays a crucial role in the clinical management of large-vessel vasculitis, providing unique information for diagnosis, disease monitoring, and treatment guidance.
Article
Clinical Neurology
Jae W. Song, Athanasios Pavlou, Jiayu Xiao, Scott E. Kasner, Zhaoyang Fan, Steven R. Messe
Summary: Plaque enhancement, positive remodeling, T1 hyperintensity, and surface irregularity are strong imaging biomarkers of symptomatic plaque in patients with ischemic events. Plaque enhancement remains significant in various subgroup analyses and shows stronger associations in certain circumstances. Future studies with larger sample sizes are needed to further evaluate plaque enhancement as a predictive marker for stroke recurrence.
Review
Computer Science, Information Systems
Mohammad Raihan Goni, Nur Intan Raihana Ruhaiyem, Muzaimi Mustapha, Anusha Achuthan, Che Mohd Nasril Che Mohd Nassir
Summary: This article provides a comprehensive review of the importance of deep learning-based blood vessel segmentation of the brain in early detection and treatment of cerebrovascular diseases.
Review
Chemistry, Analytical
Marcin Ciecholewski, Michal Kassjanski
Summary: This paper discusses the significance of liver blood vessel segmentation and presents the most advanced and effective methods. It categorizes segmentation methods into three groups, discusses their theoretical and practical characteristics, highlights pros and cons, and suggests the need for further improvements to address existing deficiencies and constraints.
Review
Chemistry, Inorganic & Nuclear
Nuria Genicio, Manuel Banobre-Lopez, Olli Grohn, Juan Gallo
Summary: Magnetic Resonance Imaging (MRI) with contrast agents (CA) is a powerful tool in providing crucial information, though challenges remain in quantifying specific functional or metabolic processes. The ratiometric approach using two different MR acquisitions shows potential to enhance MRI utility, with new generation ratiometric probes being developed for improved application. The development of new CAs and ratiometric probes aims to better diagnose and monitor physiological and pathological conditions in the body.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Engineering, Biomedical
Cheng Chen, Kangneng Zhou, Xiaoyu Guo, Zhiliang Wang, Ruoxiu Xiao, Guangzhi Wang
Summary: Phase-Contrast Magnetic Resonance Angiography (PC-MRA) is a potential method for cerebrovascular imaging, but it often has noise and broken vessels. This study used the Dempster-Shafer evidence theory to fuse features from different models and proposed a vessel thinning and completion method. Experimental results show the effectiveness of this method and the completion vessels can improve the matching ratio with CE-MRA.
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
(2022)
Article
Rheumatology
Christian Dejaco, Sofia Ramiro, Milena Bond, Philipp Bosch, Cristina Ponte, Sarah Louise Mackie, Thorsten A. Bley, Daniel Blockmans, Sara Brolin, Ertugrul Cagri Bolek, Rebecca Cassie, Maria C. Cid, Juan Molina-Collada, Bhaskar Dasgupta, Berit Dalsgaard Nielsen, Eugenio De Miguel, Haner Direskeneli, Christina Duftner, Alojzija Hocevar, Anna Molto, Valentin Sebastian Schaefer, Luca Seitz, Riemer H. J. A. Slart, Wolfgang A. Schmidt
Summary: This study updates the EULAR recommendations for the use of imaging modalities in primary large vessel vasculitis (LVV). A systematic literature review was conducted to collect new evidence on ultrasound, MRI, CT, and FDG-PET for diagnosis, monitoring, and outcome prediction in LVV. The study provides three overarching principles and eight recommendations, including the recommendation to use ultrasound as the first-line imaging test for all patients suspected of giant cell arteritis.
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Article
Clinical Neurology
Tomas Uher, Manuela Vaneckova, Jan Krasensky, Lukas Sobisek, Michaela Tyblova, Jana Volna, Zdenek Seidl, Niels Bergsland, Michael G. Dwyer, Robert Zivadinov, Nicola De Stefano, Maria Pia Sormani, Eva Kubala Havrdova, Dana Horakova
MULTIPLE SCLEROSIS JOURNAL
(2019)
Article
Clinical Neurology
Tomas Uher, Manuela Vaneckova, Jan Krasensky, Lukas Sobisek, Michaela Tyblova, Jana Volna, Zdenek Seidl, Niels Bergsland, Michael G. Dwyer, Robert Zivadinov, Nicola De Stefano, Maria Pia Sormani, Eva Kubala Havrdova, Dana Horakova
MULTIPLE SCLEROSIS JOURNAL
(2019)
Article
Clinical Neurology
D. Jakimovski, S. Gandhi, I. Paunkoski, N. Bergsland, J. Hagemeier, D. P. Ramasamy, D. Hojnacki, C. Kolb, R. H. B. Benedict, B. Weinstock-Guttman, R. Zivadinov
EUROPEAN JOURNAL OF NEUROLOGY
(2019)
Article
Clinical Neurology
Suyog Pol, Michele Sveinsson, Michelle Sudyn, Natan Babek, Danielle Siebert, Nicola Bertolino, Claire M. Modica, Marilena Preda, Ferdinand Schweser, Robert Zivadinov
JOURNAL OF NEUROIMAGING
(2019)
Article
Clinical Neurology
Nicole Ziliotto, Robert Zivadinov, Dejan Jakimovski, Marcello Baroni, Veronica Tisato, Paola Secchiero, Niels Bergsland, Deepa P. Ramasamy, Bianca Weinstock-Guttnan, Francesco Bernardi, Murali Ramanathan, Giovanna Marchetti
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2019)
Editorial Material
Hematology
Nicole Ziliotto, Robert Zivadinov, Dejan Jakimovski, Niels Bergsland, Deepa P. Ramasamy, Bianca Weinstock-Guttman, Murali Ramanathan, Giovanna Marchetti, Francesco Bernardi
THROMBOSIS AND HAEMOSTASIS
(2019)
Article
Clinical Neurology
Robert Zivadinov, Jennie Medin, Nasreen Khan, Jonathan R. Korn, Tanuja Chitnis, Robert T. Naismith, Enrique Alvarez, Michael G. Dwyer, Niels Bergsland, Ellen Carl, Diego Silva, Bianca Weinstock-Guttman
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2019)
Article
Clinical Neurology
Tom A. Fuchs, Caila B. Vaughn, Ralph H. B. Benedict, Bianca Weinstock-Guttman, Sanjeevani Choudhery, Keith Carolus, Patrick Rooney, Kira Ashton, Deepa P. Ramasamy, Dejan Jakimovski, Robert Zivadinov, Michael G. Dwyer
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2019)
Article
Clinical Neurology
R. Zivadinov, D. Horakova, N. Bergsland, J. Hagemeier, D. P. Ramasamy, T. Uher, M. Vaneckova, E. Havrdova, M. G. Dwyer
AMERICAN JOURNAL OF NEURORADIOLOGY
(2019)
Article
Neurosciences
Yanis Taege, Jesper Hagemeier, Niels Bergsland, Michael G. Dwyer, Bianca Weinstock-Guttman, Robert Zivadinov, Ferdinand Schweser
Article
Neurosciences
Suyog Pol, Ferdinand Schweser, Nicola Bertolino, Marilena Preda, Michele Sveinsson, Michelle Sudyn, Natan Babek, Robert Zivadinov
EXPERIMENTAL NEUROLOGY
(2019)
Meeting Abstract
Clinical Neurology
H. N. Beadnall, L. Ly, C. Wang, J. Barton, T. A. Hardy, R. Zivadinov, M. H. Barnett
MULTIPLE SCLEROSIS JOURNAL
(2019)
Review
Cell Biology
Yi Guan, Dejan Jakimovski, Murali Ramanathan, Bianca Weinstock-Guttman, Robert Zivadinov
NEURAL REGENERATION RESEARCH
(2019)
Meeting Abstract
Clinical Neurology
Dejan Jakimovski, Robert Zivadinov, Jesper Hagemeier, Niels Bergsland, Bianca Weinstock-Guttman, Channa Kolb, David Hojnacki, Ralph Benedict, Michael Dwyer
Meeting Abstract
Clinical Neurology
Robert Zivadinov, Chakkarin Burudpakdee, Michael G. Dwyer, Niels Bergsland, Jeffrey Chavin, Karthinathan Thangavelu, Matt Mandel, Stanley Cohan
MULTIPLE SCLEROSIS JOURNAL
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
Slimane Tounekti, Mahdi Alizadeh, Devon Middleton, James S. Harrop, Bassem Hiba, Laura Krisa, Choukri Mekkaoui, Feroze B. Mohamed
Summary: This study proposes and demonstrates a new method combining reduced field-of-view strategy with phase segmented EPI to address geometric distortion in post-operative DTI scans of patients with metal implants. The results show that the new method outperforms traditional techniques in reducing distortion.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Silvia Minosse, Eliseo Picchi, Valentina Ferrazzoli, Noemi Pucci, Valerio Da Ros, Raffaella Giocondo, Roberto Floris, Francesco Garaci, Francesca Di Giuliano
Summary: The aim of this study was to investigate the variation of DCE-MRI-derived kinetic parameters in brain tumors as a function of acquisition time. The results showed that K-ep and V-e were time-dependent and required longer scan times to obtain reliable parameter values, while K-trans was time-independent and remained the same in all acquisition times, making it a reliable parameter for short acquisition times.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xingmin Guan, Xinheng Zhang, Hsin-Jung Yang, Rohan Dharmakumar
Summary: This study aims to investigate why DIR-prepared dark-blood T2* weighted images have lower SNR, CNR, and diagnostic accuracy for intramyocardial hemorrhage (IMH) detection compared to non-DIR-prepared bright-blood T2* images. Through phantom and animal studies, it was confirmed that the signal loss on DIR-prepared T2* images mainly originates from spin-relaxation during the DIR preparation. Therefore, when used for IMH detection, extra attention should be paid to the SNR of DIR-prepared dark-blood T2* imaging protocols.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Beatriz Laureano, Hassna Irzan, Helen OReilly, Sebastian Ourselin, Neil Marlow, Andrew Melbourne
Summary: Prematurity and preterm stressors have significant effects on the development of infants, especially at earlier gestations. While neonatal care advances have reduced preterm mortality rates, disability rates continue to grow in middle-income settings. Imaging the preterm brain using MR technology has improved our understanding of its development and the affected regions and networks. This research aims to support interventions, improve neurodevelopment, and provide accurate prognoses for preterm infants. This study focuses on the fully developed brain of extremely preterm subjects and examines myelin-related biomarkers to assess long-term effects. The findings suggest altered connectivity and cognitive outcomes in the adult preterm brain.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Julian Rauch, Frederik B. Laun, Peter Bachert, Mark E. Ladd, Tristan A. Kuder
Summary: This study presents a method for reducing concomitant field effects in double diffusion encoding (DDE) sequences by adding oscillating gradient pulses. The modified sequences successfully reduced accumulated concomitant phase without significant changes in the original sequence characteristics. The proposed method led to an increase in signal-to-noise ratio (SNR) for phantom and in vivo experiments, supported by simulations.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marlon Bran Lorenzana, Shekhar S. Chandra, Feng Liu
Summary: Sparse reconstruction is important in MRI for reducing acquisition time and improving spatial-temporal resolution. This paper introduces two decoupling techniques for explicit 1D regularization and a combined 1D + 2D reconstruction technique that improves image quality.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yifan Gou, W. Christopher Golden, Zixuan Lin, Jennifer Shepard, Aylin Tekes, Zhiyi Hu, Xin Li, Kumiko Oishi, Marilyn Albert, Hanzhang Lu, Peiying Liu, Dengrong Jiang
Summary: ARTS algorithm improves the reliability of Y-v estimation in noncompliant subjects, enhancing the utility of Y-v as a biomarker for brain diseases.
MAGNETIC RESONANCE IMAGING
(2024)