Ex vivo continuous glucose monitoring with microdialysis technique: The example of GlucoDay

The use of a glucose biosensor in conjunction with a microdialysis probe used to sample the interstitial fluid of the patient has been demonstrated to be extremely useful and advantageous for obtaining a continuous glucose monitoring instrument capable of detecting glycemic level in real time for a long period. The first example of this kind of instrument which was cleared for commercialization is the GlucoDay made by Menarini. The approach used by the GlucoDay presents several advantages if compared with other instruments and its features and future prospective are thoroughly discussed.