VCSEL optoelectronic biosensor for detection of infectious diseases

We report on the detection of human anti-dengue antibodies from serum samples using a compact optoelectronic label-free biosensor. The system consists of a tunable vertical-cavity surface-emitting laser, guided-mode resonant sensor surface, and two silicon pin detectors. This novel biosensor demonstrated sufficient sensitivity in a clinical-relevant assay, making it a potential new platform for simplified and rapid point-of-care diagnostic tests for the detection of infectious diseases.