Article
Endocrinology & Metabolism
Abbass Ghanbari-Niaki, Fahimeh Hosseini, David Robert Broom, Bahareh Tejenjari, Saleh Rahmati-Ahmadabad
Summary: This study investigated the effects of high-intensity training and Ziziphus jujuba extract on tissue nesfatin-1 in rats. The results showed that nesfatin-1 concentration and ATP concentration were increased in trained rats. High-intensity training also increased plasma HDL and insulin concentration and decreased plasma TG and cortisol. Ziziphus jujuba extract only increased heart ATP concentration. The combination of exercise and Ziziphus jujuba extract had additive effects on nesfatin-1 gene expression and concentration in various tissues, as well as plasma HDL and cortisol concentration. Further research is needed to confirm these findings in humans.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Multidisciplinary Sciences
Marek Popowczak, Andrzej Rokita, Dawid Kozlenia, Jaroslaw Domaradzki
Summary: Increased resting blood pressure is a risk factor for health complications, and its prevalence is growing among adolescents. This study investigated the effect of a 10-weeks HIIT-Tabata protocol introduced in physical education lessons on resting blood pressure in adolescents. The results showed that HIIT effectively decreases blood pressure, suggesting its implementation in secondary school PE lessons to improve blood pressure parameters.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Natalia Turri-Silva, Amanda Vale-Lira, Kenneth Verboven, Joao Luiz Quaglioti Durigan, Dominique Hansen, Gerson Cipriano
Summary: This study preliminarily assessed the effects of high-intensity exercise training modalities on heart failure patients, showing that both HIIT and CRT positively impacted cardiorespiratory fitness, with only HIIT improving isokinetic torque peak and CRT reducing chair stand test completion time. Further research with a larger cohort is needed to confirm these findings.
Article
Multidisciplinary Sciences
Natalia Turri-Silva, Amanda Vale-Lira, Kenneth Verboven, Joao Luiz Quaglioti Durigan, Dominique Hansen, Gerson Cipriano Jr
Summary: The study aimed to assess the effects of high-intensity exercise training modalities on heart failure patients, showing positive impacts on cardiorespiratory fitness and physical performance. While both HIIT and CRT improved VO2 peak and METs, only HIIT increased isokinetic torque peak. Further research with larger cohort is needed to confirm these findings.
Review
Cardiac & Cardiovascular Systems
Ahmad Sabbahi, Justin M. Canada, Abraham Samuel Babu, Richard Severin, Ross Arena, Cemal Ozemek
Summary: Cardiac rehabilitation programs are standard-of-care in cardiovascular medicine. Aerobic exercise training is crucial for improving cardiorespiratory fitness.
PROGRESS IN CARDIOVASCULAR DISEASES
(2022)
Article
Medicine, General & Internal
Ida Almenning Kiel, Helen Jones, Sofie Lionett, Ragnhild Rosbjorgen, Stian Lydersen, Eszter Vanky, Trine Moholdt
Summary: This study found little difference in cardiovascular disease (CVD) risk factors between women with and without polycystic ovary syndrome (PCOS) at baseline, but some indications of endothelial dysfunction in women with PCOS.
JOURNAL OF CLINICAL MEDICINE
(2022)
Editorial Material
Endocrinology & Metabolism
Niklas Joisten, Sebastian Gehlert, Philipp Zimmer
Summary: High-intensity interval training (HIIT) is a common method used to improve athletic performance, aid in rehabilitation, and prevent diseases. However, research suggests that exceeding a certain limit of HIIT might have detrimental effects on metabolic health.
TRENDS IN ENDOCRINOLOGY AND METABOLISM
(2022)
Article
Geriatrics & Gerontology
James E. M. Blackwell, Nima Gharahdaghi, Matthew S. Brook, Shinya Watanabe, Catherine L. Boereboom, Brett Doleman, Jonathan N. Lund, Daniel J. Wilkinson, Kenneth Smith, Philip J. Atherton, John P. Williams, Bethan E. Phillips
Summary: The study found that in octogenarians with comorbidities, high-intensity interval training (HIIT) can improve cardiorespiratory fitness and muscle mass, including reducing fat mass and increasing muscle synthesis rates.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Review
Endocrinology & Metabolism
Angelo Sabag, Loren Barr, Mike Armour, Alex Armstrong, Callum J. Baker, Stephen M. Twigg, Dennis Chang, Daniel A. Hackett, Shelley E. Keating, Jacob George, Nathan A. Johnson
Summary: Recent studies have shown that high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) both lead to reductions in liver fat content, with HIIT demonstrating comparable improvements to MICT despite requiring less energy and time commitment. Further research is needed to determine the relative importance of aerobic exercise prescription variables, such as intensity, on liver fat.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Peripheral Vascular Disease
Vicente Avila-Gandia, Domingo Jesus Ramos-Campo, Esther Garcia-Sanchez, Antonio Jesus Luque-Rubia, Asensio Lopez, Francisco Javier Lopez-Roman
Summary: This study aimed to analyze the effect of training, detraining, and retraining on cardiovascular risk factors in hypertensive patients. The results showed that training improved blood pressure, body composition, lipid profile, glucose levels, and cardiovascular fitness.
JOURNAL OF HYPERTENSION
(2023)
Article
Clinical Neurology
Thalia Lapointe, Julie Houle, Ying-Tung Sia, Marika Payette, Francois Trudeau
Summary: This study aimed to compare the effects of a 6-month exercise program with either MICT only or a combination of HIIT and MICT on cardiorespiratory fitness, cardiovascular risk factors, functionality, cognitive function, and depression markers among stroke or TIA patients. The results showed that both HIIT + MICT and MICT programs had similar improvements in cardiorespiratory fitness, self-reported physical activity, and anxiety and depression markers.
FRONTIERS IN NEUROLOGY
(2023)
Article
Biochemistry & Molecular Biology
Aline Meza-Ramos, Anna Alcarraz, Marta Lazo-Rodriguez, Gemma Sanguesa, Elisenda Banon-Maneus, Jordi Rovira, Maria Jose Ramirez-Bajo, Marta Sitges, Lluis Mont, Pedro Ventura-Aguiar, Montserrat Batlle, Eduard Guasch
Summary: Although the benefits of moderate exercise are well established, the effects of strenuous exercise in high cardiovascular risk individuals are still unclear. This study showed that moderate exercise had the most intense cardiovascular benefits, while intense training only partially reversed them.
Article
Medicine, General & Internal
Ladislav Batalik, Garyfallia Pepera, Jannis Papathanasiou, Sebastian Rutkowski, David Liska, Katerina Batalikova, Martin Hartman, Marian Felsoci, Filip Dosbaba
Summary: Telehealth cardiac rehabilitation is a feasible and effective alternative to conventional outpatient CR, with similar training intensities and safety profiles for CAD patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Physiology
Matthew T. Farrow, Jennifer Maher, Dylan Thompson, James L. J. Bilzon
Summary: A randomized controlled trial will be conducted to determine the effectiveness of a 6-week home-based upper-body high-intensity interval training intervention on biomarkers of cardiometabolic health in individuals with spinal cord injury. Participants will be assigned to either the HIIT or control group, with assessments on body composition, glycaemic control, blood lipids, inflammation, aerobic capacity, physical activity, and subjective measures of health.
EXPERIMENTAL PHYSIOLOGY
(2021)
Review
Multidisciplinary Sciences
Jacob M. McDougle, Gerald T. Mangine, Jeremy R. Townsend, Adam R. Jajtner, Yuri Feito
Summary: A scoping review was conducted to investigate the acute physiological response to HIFT-based exercise. The review found that markers of intensity were consistently assessed, supporting the idea that HIFT workouts are performed at high-intensity. However, the inclusion of other measures has been inconsistent, limiting the ability to draw generalized conclusions.
Article
Sport Sciences
Andrew Haynes, Joanne McVeigh, Leanne Lester, Peter R. Eastwood, Leon Straker, Trevor A. Mori, Lawrence Beilin, Daniel J. Green
Summary: TV watching habits during childhood and adolescence have a negative impact on cardiorespiratory fitness in adulthood, but this impact can be attenuated by engaging in higher levels of physical activity in adulthood.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Article
Sport Sciences
Andrea Tryfonos, Debar Rasoul, Daniel Sadler, James Shelley, Joseph Mills, Daniel J. Green, Ellen A. Dawson, Matthew Cocks
Summary: This study found that exercise-induced elevations in conduit artery shear rate increase eNOS Ser(1177) phosphorylation but not PECAM-1 Tyr(713) phosphorylation. This suggests that PECAM-1 phosphorylation may not be involved in the vascular response to acute but prolonged elevations in exercise-induced shear rate in healthy, active men.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Article
Physiology
Andrea Tryfonos, Joseph Mills, Daniel J. Green, Anton J. M. Wagenmakers, Ellen A. Dawson, Matthew Cocks
Summary: This study examined the relationships between in vivo measures of vascular function and the expression of atherogenic risk-modulating proteins in endothelial cells (ECs) isolated from the radial artery of CAD patients. The results revealed a difference in the regulation of endothelium-dependent vasodilation measured in vivo between patients with CAD compared to previously reported data in subjects without a clinical diagnosis, suggesting that eNOS Ser(1177) phosphorylation may be the key to maintain vasodilation in CAD patients.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Maxime Boidin, Ellen A. Dawson, Dick H. J. Thijssen, Robert M. Erskine
Summary: This study used a within-subject, cross-over design to investigate the relationship between individual adaptations to resistance training (RT) and endurance training (END). The findings indicated that there was no correlation between the adaptations to both types of training. However, a significant interaction was observed between the VEGFA genotype and training modality, suggesting that individuals with the VEGFA GG genotype exhibited greater adaptations to RT compared to END.
MOLECULAR GENETICS AND GENOMICS
(2023)
Article
Cardiac & Cardiovascular Systems
Hannah J. Thomas, Channa E. Marsh, Leanne Lester, Barbara A. Maslen, Louise H. Naylor, Daniel J. Green
Summary: This study compared the differences in cardiovascular risk factor responses between males and females following endurance and resistance training. It found that males had a larger improvement in peak oxygen consumption following endurance training and strength following resistance training compared to females, but these changes did not translate to changes in other cardiovascular risk factors.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2023)
Article
Nutrition & Dietetics
Andrea Tryfonos, Matthew Cocks, Nicola Browning, Ellen A. Dawson
Summary: Acute exercise can temporarily decrease endothelial functions and release extracellular vesicles (EVs). This study compared the time course of endothelial responses to moderate-intensity continuous exercise (MICE) and high-intensity interval exercise (HIIE) and found that both exercises improved endothelial function but with different time courses.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2023)
Article
Physiology
Howard H. Carter, Jem L. Cheng, Maureen J. MacDonald, Oliver Pienaar, Alexander Coleman, Louise H. Naylor, Daniel J. Green
Summary: This study investigated the effects of exercise in 32 °C and 38 °C water on flow-mediated dilation (FMD). The results showed that exercise in water can decrease brachial artery shear and FMD compared to land-based exercise, and exercise in 38 °C water can increase brachial shear and FMD.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2023)
Article
Endocrinology & Metabolism
Jeff S. Coombes, Katrin A. Dias, Ravin Lal, Robert G. Fassett, Matthew P. Wallen, Joyce S. Ramos, Suzanna Russell, Natalie K. Vear, Trishan Gajanand, Tom G. Bailey, Daniel J. Green, Brooke K. Coombes, Llion A. Roberts
Summary: This study aimed to determine the efficacy of external counterpulsation (ECP) on glycemic control in people with type 2 diabetes mellitus (T2D), and investigate any persistent effects 7 weeks after treatment. The results showed that after 7 weeks, the ECP45 group had significantly lower levels of HbA1c compared to the SHAM control group. The findings demonstrate that ECP45 for 7 weeks can improve glycemic control in people with T2D.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Article
Peripheral Vascular Disease
Daniel J. J. Green, Channa E. E. Marsh, Hannah J. J. Thomas, Leanne Lester, Katrina J. J. Scurrah, Andrew Haynes, Louise H. H. Naylor
Summary: This study recruited 90 same-sex twins and found that both aerobic and resistance training can improve vascular function, with a more pronounced response in females. Most individuals respond to one or both forms of training, which has important implications for individualized exercise programs.
Review
Endocrinology & Metabolism
Daniel J. Green, Lauren C. Chasland, Louise H. Naylor, Bu B. Yeap
Summary: Middle-aged and older men with comorbidities, sedentary lifestyle, and lower testosterone levels are at higher risks for cardiometabolic disease. Exercise training is effective in improving cardiometabolic health, while testosterone treatment shows potential benefits in reducing type 2 diabetes risk. However, the causal relationship between testosterone and cardiovascular risk remains unclear. Therefore, supervised exercise programs incorporating aerobic and resistance training can effectively improve cardiometabolic health in this population, and the combination with testosterone treatment could be considered for further research.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Microbiology
Adilah F. Ahmad, Jose A. Caparros-Martin, Silvia Lee, Fergal O'Gara, Bu B. Yeap, Daniel J. Green, Mohammed Ballal, Natalie C. Ward, Girish Dwivedi
Summary: This observational cohort study found that there were no significant differences in gut bacterial diversity between obese patients before and after bariatric surgery compared to a healthy control group. However, there were differences in the abundance of certain bacterial groups between the two cohorts. Additionally, the study observed changes in the levels of specific short chain fatty acids and soluble CD14 and CD163 in obese patients before and after surgery compared to healthy controls.