Therapeutic polo-like kinase 1 inhibition results in mitotic arrest and subsequent cell death of blasts in the bone marrow of AML patients and has similar effects in non-neoplastic cell lines
Therapeutic polo-like kinase 1 inhibition results in mitotic arrest and subsequent cell death of blasts in the bone marrow of AML patients and has similar effects in non-neoplastic cell lines
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关键词
AML, PLK1 inhibition, BI2536, BI6727, Volasertib, Bone marrow biopsy, Live cell imaging, Hematopoietic cells
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