Article
Environmental Sciences
Vahid Beiki, Seyyed Mohammad Mousavi, Tannaz Naseri
Summary: In recent years, the production of electronic waste (e-waste) has increased due to population growth and high consumption. The high concentration of heavy elements in these wastes has caused environmental problems. However, electronic waste is considered a secondary mineral for the recovery of valuable elements, such as Cu and Au. The recovery of metals from spent telecom-munication printed circuit boards (STPCBs) is significant, but it has been overlooked despite its high global production. This study isolated a cyanogenic bacterium from soil and found it could produce cyanide in a specific culture medium. The one-step bioleaching method was used to recover 98.2% of Cu from STPCBs powder, and the structural analysis confirmed the high Cu recovery.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Review
Engineering, Environmental
Emmanuel Yaw Owusu-Fordjour, Xinbo Yang
Summary: Bioleaching, using microorganisms to dissolve minerals and extract Rare Earth Elements (REEs) in aqueous media, has gained attention for its potential eco-friendliness compared to other extraction methods. Mixed culture bioleaching is preferred for efficient REEs extraction, promoting closed-loop recycling and reducing supply chain issues. This literature review provides an overview of challenges, opportunities, microorganisms, mechanisms, approaches, parameters, and techno-economic considerations related to REEs bioleaching, and offers recommendations for future advancements.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Acoustics
Yongheng Zhong, Tao Xu, Shengyang Ji, Xiaodan Wu, Tian Zha, Shimin Li, Peng Zhang, Kaimian Li, Baiyi Lu
Summary: The study found that ultrasonic pretreatment (UPT) is an effective way to remove cyanide from cassava in a short period of time, enhancing the safety of cassava. UPT can improve the processing of cassava by directly eliminating hydrogen cyanide and indirectly degrading cyanogenic glycosides, while also promoting enzymatic hydrolysis.
ULTRASONICS SONOCHEMISTRY
(2021)
Review
Biotechnology & Applied Microbiology
Biljana S. Maluckov
Summary: Microorganisms play a crucial role in geological transformations, facilitating the mobility of metals and formation of new minerals for practical applications in metal recovery, including the formation of nanogold and nanogold compounds.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Marta Boter, Isabel Diaz
Summary: Plants and phytophagous arthropods have coevolved in a battle for survival, with plants producing antiherbivore chemicals and herbivores adapting to their hosts. Cyanogenic glucosides are defense chemicals produced by cyanogenic plants, while the Brassicaceae family has evolved an alternative pathway to produce cyanohydrin. When a plant tissue is damaged, cyanogenic substrates come into contact with degrading enzymes, releasing toxic cyanide and derived compounds. This review focuses on the plant metabolic pathways linked to cyanogenesis and highlights its role as a defense mechanism against herbivores, discussing the potential of cyanogenesis-derived molecules for pest control strategies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Manthos Panou, Spyros Gkelis
Summary: This study isolated and characterized 81 strains of cyanobacteria from different environments, resulting in the description of five new genera and four new species. The widespread production of HCN among different taxa and habitats was reported for the first time, showcasing novel cyanobacteria diversity.
MOLECULAR PHYLOGENETICS AND EVOLUTION
(2022)
Article
Plant Sciences
M. N. Sohail, A. A. Quinn, C. K. Blomstedt, R. M. Gleadow
Summary: Droughted sorghum, both wildtype and dhurrin-lacking mutants, had higher concentrations of reactive oxygen species (ROS). Dhurrin increased in wildtype genotypes with drought. Sorghum bicolor is tolerant of high temperatures and prolonged droughts. During droughts, concentrations of dhurrin increase posing a risk to livestock of hydrogen cyanide poisoning.
Article
Chemistry, Multidisciplinary
Fariborz Faraji, Jingxiu Wang, Harshit Mahandra, Ahmad Ghahreman
Summary: This study conducted a comprehensive investigation on the role of pH in Bacillus megaterium bacterial growth, cyanide production, and gold recovery, demonstrating the high efficiency of maximizing biogenic cyanide for gold recovery. The results showed the potential of biocyanidation as a viable technique for industrial applications, eliminating the need for biooxidation and comparing favorably to conventional chemical leaching methods in gold recovery.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Pharmacology & Pharmacy
S. Sreejith, Joseph Tom, V. P. Sangeetha, U. Vandana, Joseph Xavier, C. A. Jayaprakas, P. Mohanan
Summary: The study tested the cytotoxic effect of cassava cyanide extract (CCE) on human glioblastoma cells (LN229). The results showed that CCE had a dose-dependent toxicity on glioblastoma cells, reducing cell viability by negatively affecting mitochondrial activity, lysosomal and cytoskeletal integrity. The CCE also interfered with the cell cycle and induced cell death, suggesting its potential as an antineoplastic agent against glioblastoma cells.
Review
Environmental Sciences
Trung Hau Nguyen, Sangmin Won, Myung-Gyu Ha, Dinh Duc Nguyen, Ho Young Kang
Summary: The industrial evolution has led to the release of a large amount of toxic metals and metalloids into the environment, posing risks to both ecological systems and human health. Bioleaching is a preferable, cost-effective and environmentally safe option for removing these toxic substances.
Article
Green & Sustainable Science & Technology
Fariborz Faraji, Harshit Mahandra, Ahmad Ghahreman
Summary: This study investigates the effect of amino acids on the production of bio-cyanide using Bacillus megaterium. It is found that glycine yields a higher concentration of bio-cyanide compared to threonine and glutamine. Optimization experiments reveal that the optimal medium for bio-cyanide production does not contain threonine and can achieve gold leaching efficiency comparable to chemical cyanide.
Article
Engineering, Environmental
Chenxi Pang, Mi Lin, Yusen Wu, Jujun Ruan
Summary: This study presents an innovative bioleaching technique that increases cyanide production and reduces leaching time, achieving efficient recovery of precious metals from waste central processing unit slots.
RESOURCES CONSERVATION AND RECYCLING
(2023)
Review
Engineering, Chemical
Marta Ruiz-Bermejo, Jose Luis de la Fuente, Cristina Perez-Fernandez, Eva Mateo-Marti
Summary: HCN-derived polymers, synthesized from HCN or its derivatives, have diverse potential applications in prebiotic chemistry and astrobiology. The real structures and formation pathways of these polymers have not been fully elucidated, but they are considered keys in the formation of protometabolic and informational systems.
Article
Optics
Georg Ch Mellau, Vladimir Yu Makhnev, Iouli E. Gordon, Nikolay F. Zobov, Jonathan Tennyson, Oleg L. Polyansky
Summary: A newly developed hydrogen cyanide line list with higher accuracy and completeness for the HITRAN spectroscopic database is presented. By combining experimental results and new variational calculation methods, accurate and complete line lists can be obtained. Through validation against experimental results, the accuracy of the line list is confirmed.
JOURNAL OF QUANTITATIVE SPECTROSCOPY & RADIATIVE TRANSFER
(2021)
Article
Chemistry, Applied
Yongheng Zhong, Tao Xu, Xiaodan Wu, Kaimian Li, Peng Zhang, Shengyang Ji, Shimin Li, Lufei Zheng, Baiyi Lu
Summary: This paper evaluated the dietary risks of cassava cyanide and proposed a maximum residue limit for cyanogenic glycosides in cassava. The results showed no chronic health risk across all populations concerning cassava consumption. It is suggested that risk assessment of cyanide for foods rich in CNGs should be based on CNGs quantification rather than that of CN-.
Article
Chemistry, Multidisciplinary
Saeed Babaee, Mohammad Ali Zolfigol, Gholamabbas Chehardoli, Mohammad Ali Faramarzi, Somayeh Mojtabavi, Tahmineh Akbarzadeh, Roshanak Hariri, Arezoo Rastegari, Farshad Homayouni Moghadam, Mohammad Mahdavi, Zahra Najafi
Summary: A new class of indolotacrine hybrids was designed, synthesized, and assessed as acetylcholinesterase inhibitors (AChEIs). Some of the derivatives showed good inhibitory effect against acetylcholinesterase. The cyclopenta-indolotacrine hybrids demonstrated slightly better anti-AChE activity than cyclohexa-indolotacrine hybrids. Compound 8g showed the best AChE inhibitory activity and acted as a competitive inhibitor.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2023)
Article
Food Science & Technology
Somayeh Mojtabavi, Farnoosh Rezayaraghi, Tina Adelpour, Fatemeh Kiaei, Mohammad-Reza Delnavazi, Mohammad Ali Faramarzi
Summary: In this study, a novel type of nanofibers loaded with quercetin were fabricated. These nanofibers showed improved stability and were able to inhibit bacteria and protect oil. Therefore, they have great potential for various applications.
FOOD AND BIOPROCESS TECHNOLOGY
(2023)
Article
Chemistry, Physical
Ebrahim Saeedian Moghadam, Abdullah Mohammed Al-Sadi, Thuraya Al-Harthy, Mohammad Ali Faramarzi, Musa Shongwe, Mohsen Amini, Raid Abdel-Jalil
Summary: Diabetes, a chronic metabolic disorder, is a global health concern. In this study, a series of piperazin-1-yl benzimidazole-2-carbamates derivatives were synthesized and evaluated for their potential as α-glucosidase inhibitors. Among them, 7d-1 and 7f-2 showed the highest inhibitory activity with IC50 values of 118 and 155 μM, respectively. Kinetic studies revealed that 7d-1 is a competitive inhibitor of α-glucosidase. Molecular docking analysis provided insights into the binding interactions between these bioactive organic molecules and the amino acid residues at the active site of the enzyme.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Physical
Mahtab Shokri, Sara Tarighi, Mohammad Ali Faramarzi, Samahe Sadjadi, Soamyeh Mojtabavi
Summary: In this study, two ZSM-5 zeolites with different SiO2/Al2O3 ratios of 200 and 80 were synthesized and functionalized to prepare four biocatalysts for acid orange-7 dye degradation. The results showed that functionalization improved the performance and stability of the catalysts, and the SiO2/Al2O3 ratio had little effect on the stability of the catalysts.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Multidisciplinary Sciences
RasaDokht Forozan, Minoo Khalili Ghomi, Aida Iraji, Mohammad Nazari Montazer, Milad Noori, Navid Dastyafteh, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Seyed Esmaeil Sadat-Ebrahimi, Bagher Larijani, Shahrzad Javanshir, Mohammad Mahdavi
Summary: A new series of thioquinoline compounds with phenylacetamide were synthesized and their structures were confirmed. The synthesized compounds showed potent inhibitory activities against α-glucosidase, surpassing the standard inhibitor acarbose. The most effective compound, 9m, exhibited competitive inhibition with α-glucosidase through various interactions.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Mina Saeedi, Roshanak Hariri, Aida Iraji, Ali Ahmadi, Somayeh Mojtabavi, Shiva Golshani, Mohammad Ali Faramarzi, Tahmineh Akbarzadeh
Summary: In this study, various N'-substituted benzylidene benzohydrazide-1,2,3-triazoles were designed, synthesized, and evaluated for their inhibitory activity against alpha-glucosidase. The structures of the derivatives were confirmed using multiple spectroscopic techniques. All derivatives exhibited potent inhibition, with IC50 values ranging from 0.01 to 648.90 μM, compared to acarbose as the positive control (IC50 = 752.10 μM). Compounds 7a and 7h showed significant potency, with IC50 values of 0.02 and 0.01 μM, respectively. Further studies revealed that these compounds are noncompetitive inhibitors of alpha-glucosidase. Fluorescence quenching and molecular docking were also used to investigate the interaction and binding mechanisms between the inhibitors and the target enzyme.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Sara Moghadam Farid, Milad Noori, Mohammad Nazari Montazer, Minoo Khalili Ghomi, Marjan Mollazadeh, Navid Dastyafteh, Cambyz Irajie, Kamiar Zomorodian, Seyedeh Sara Mirfazli, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Bagher Larijani, Aida Iraji, Mohammad Mahdavi
Summary: Different s-substituted benzimidazole-thioquinoline derivatives were synthesized and evaluated for their potential alpha-glucosidase inhibitory activities. The most active compound, 6j (X = 4-bromobenzyl), exhibited significant potency with an IC50 value of 28.0 +/- 0.6 μM, compared to the positive control acarbose with an IC50 value of 750.0 μM. Molecular dynamics simulations and in silico pharmacodynamics and ADMET properties were performed to assess the interactions and druggability of the derivatives. Overall, these derivatives show promise as potential alpha-glucosidase inhibitors.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Multidisciplinary
Soheila Esmaili, Ahmad Ebadi, Ardeshir Khazaei, Hamideh Ghorbani, Mohammad Ali Faramarzi, Somayeh Mojtabavi, Mohammad Mahdavi, Zahra Najafi
Summary: A novel series of pyrano[3,2-c]quinoline-1,2,3-triazole hybrids were synthesized and evaluated for their inhibitory activity against α-glucosidase. Compound 8k exhibited the best inhibitory effect with a competitive pattern of inhibition. Molecular docking and dynamics simulations revealed that the R-enantiomer of compound 8k formed a more stable complex with higher binding affinity to the active site of α-glucosidase compared to the S-enantiomer.
Article
Chemistry, Multidisciplinary
Mehdi Emadi, Fahimeh Mosavizadeh-Marvest, Ali Asadipour, Yaghoub Pourshojaei, Samanesadat Hosseini, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Bagher Larijani, Maryam Mohammadi-Khanaposhtani, Mohammad Mahdavi
Summary: A series of new indole-carbohydrazide-phenoxy-1,2,3-triazole-N-phenylacetamide hybrids were synthesized and evaluated as α-glucosidase inhibitors. Compound 11d showed the highest potency and can be a potential lead compound for further development.
Article
Pharmacology & Pharmacy
Mohammad Dehghanizadeh Baghdadabad, Nima Naderi, Vahideh Atabaki, Mohammad Ali Faramarzi, Maryam Tabarzad, Tahereh Hosseinabadi
Summary: This study found that the polysaccharide fractions in Spirulina have significant analgesic and anti-inflammatory effects. Given that Spirulina is an easily available source of bioactive compounds, these findings provide promising leads for novel drug development.
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH
(2023)
Article
Chemistry, Physical
Hamideh Ghorbani, Ahmad Ebadi, Mohammad Ali Faramarzi, Somayeh Mojtabavi, Mohammad Mahdavi, Zahra Najafi
Summary: This study synthesized some new coumarin-fused 4H-pyran derivatives and evaluated their inhibitory activity against yeast alpha-glucosidase enzyme. All of the synthesized compounds showed significant inhibitory activity, with compound 6e exhibiting the most potent activity. Kinetic and molecular modeling studies confirmed the competitive inhibition of compound 6e against alpha-glucosidase. In silico prediction suggested that these derivatives have potential therapeutic benefits for the treatment of type 2 diabetes mellitus.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Mahtab Rahmani Gavanrudi, Mohammad Halimi, Hossein Najafzadehvarzi, Majid Alikhani, Ali Moazzam, Soghra Farzipour, Samanesadat Hosseini, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Ensieh Nasli-Esfahani, Maryam Mohammadi-Khanaposhtani, Mohammad Mahdavi
Summary: Thirteen new derivatives of phthalimide-1,2,3-triazole-N-phenylacetamide hybrids were synthesized and evaluated for their inhibitory potential against a-glucosidase. Seven compounds showed excellent inhibition (IC50 values = 1.30-31.7 μM) compared to the positive control acarbose (IC50 value = 750.1 μM), with the compound containing a 2,4-dichloro substituent on the phenyl ring being the most potent inhibitor. Molecular docking and dynamics studies were conducted to understand the interaction mode, stability, and flexibility of the most potent compounds, and in silico studies predicted their drug-likeness, pharmacokinetic, and toxicity properties.
Article
Environmental Sciences
Ghazaleh Royatvand-Ghiyasvand, Somayeh Mojtabavi, Anita Azmi, Hoda Jahandar, Mohammad Ali Faramarzi
Summary: From an environmental perspective, azo dye industrial effluent poses a significant risk to public health due to its toxic, carcinogenic, and teratogenic properties. However, enzyme-based technologies offer a promising and controllable method for removing synthetic dyes from wastewater. This study demonstrates the synthesis of hybrid nanoparticles (HNPs) with laccase as the catalyst, showing efficient removal of azo dyes and potential for wastewater treatment. Evaluation: 8 out of 10.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Sajedeh Safapoor, Mohammad Halimi, Minoo Khalili Ghomi, Milad Noori, Navid Dastyafteh, Shahrzad Javanshir, Samanesadat Hosseini, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Ensieh Nasli-Esfahani, Bagher Larijani, Azadeh Fakhrioliaei, Mohammad G. Dekamin, Maryam Mohammadi-Khanaposhtani, Mohammad Mahdavi
Summary: A new series of quinoline-quinazolinone-thioacetamide derivatives 9a-p were designed and synthesized. These compounds showed significant anti-a-glucosidase activity, with compound 9g being the most potent inhibitor. Molecular simulation studies revealed that compound 9g occupied the active site of a-glucosidase with favorable binding energy. In silico ADMET studies of the most potent compounds predicted their drug-likeness, pharmacokinetic, and toxicity properties.
Article
Multidisciplinary Sciences
Nahal Shayegan, Sirous Haghipour, Nader Tanideh, Ali Moazzam, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Cambyz Irajie, Sara Parizad, Shirin Ansari, Bagher Larijani, Samanehsadat Hosseini, Aida Iraji, Mohammad Mahdavi
Summary: In this study, new structural variants of 4-hydroxyquinolinone-hydrazones were designed and synthesized. The structure elucidation of the synthetic derivatives 6a-o was determined using various spectroscopic techniques, and their alpha-glucosidase inhibitory activity was evaluated. The synthetic molecules exhibited good alpha-glucosidase inhibition with IC50 values ranging from 93.5 +/- 0.6 to 575.6 +/- 0.4 μM, compared to the standard acarbose (IC50 = 752.0 +/- 2.0 μM). Structure-activity relationships and the mode of inhibition were established through kinetic studies and molecular docking simulations.
SCIENTIFIC REPORTS
(2023)
Article
Metallurgy & Metallurgical Engineering
Arsyad Maulana Dzulqornain, Ana Belen Cueva-Sola, Kyeong Woo Chung, Jin-Young Lee, Rajesh Kumar Jyothi
Summary: This study presents a hydrometallurgical process for the separation of light rare earth elements (LREEs) using oxidation, precipitation, solvent extraction, and stripping techniques. Selective oxidation with potassium permanganate was employed for the separation of cerium (III). Solvent extraction with Cyanex 572 and cross-current scrubbing were used to achieve the separation of lanthanum (III) from neodymium (III) and praseodymium (III).
Article
Metallurgy & Metallurgical Engineering
Bo Chen, Shenxu Bao, Yimin Zhang
Summary: This study investigated the effects of Al, Fe, P, Si and Na on the precipitation characteristics of vanadium in the ultrasound precipitation system. The concentration upper limits and the negative influence on the precipitation kinetics were determined for each impurity. The findings provide theoretical and technical support for the industrial application of ultrasound precipitation technology.
Article
Metallurgy & Metallurgical Engineering
Chunlin He, Mingwei Qi, Yun Liu, Zunzhang Liu, Yuezhou Wei, Toyohisa Fujita, Guifang Wang, Shaojian Ma, Wenchao Yang, Junyuan Gan
Summary: In this study, D201 x 7 resin and tartaric acid were used as materials and complexing agents for the separation of germanium from sulfuric acid solution. The study successfully achieved the separation of germanium and demonstrated the high selectivity and adsorption performance of the resin.
Article
Metallurgy & Metallurgical Engineering
Xiaobo Zhu, Yue Liu, Chen Ma, Wang Li
Summary: A selective and highly effective method for the extraction and separation of V(IV) and Fe(III) using N235 and P507 as solvent extractants is proposed. The pH, composition, and concentration of the extractant mixture have significant effects on the extraction efficiency and separation factor. The mixing of P507 and N235 generates the P507 monomer, which enhances the extraction efficiency and weakens the stability of vanadium containing extraction complex. Cation exchange process forms the extraction complexes.
Article
Metallurgy & Metallurgical Engineering
B. Behnajady, J. Yousefi Seyf, S. Karimi, M. Moradi, M. Sohrabi
Summary: Deep eutectic solvents (DES) have potential as environmentally-friendly solvents for recovering metals from spent lithium-ion batteries (LIBs). Experimental and molecular dynamics simulation results showed that the chloride ions in DES can form complexes with lithium, manganese, and nickel ions, facilitating their extraction.
Review
Metallurgy & Metallurgical Engineering
Sebastian Kinas, Dorota Jermakowicz-Bartkowiak, Anna Dzimitrowicz, Piotr Cyganowski
Summary: The high demand for platinum-group metals (PGMs) and Re in economical and industrial applications related to environmental protection and energy conversion/storage has led to resource scarcity. Thus, it is crucial to recover and recycle these rare metals. This study critically reviews the recent progress in the effective recovery of PGMs and Re from materials relevant to sustainable technologies, emphasizing practical aspects, environmental impact, and issues related to the unit processes of recovery.
Article
Metallurgy & Metallurgical Engineering
Guopeng Yang, Qinggang Li, Guiqing Zhang, Mingyu Wang, Zuoying Cao, Wenjuan Guan, Jiawei Du, Shengxi Wu
Summary: The study proposes an efficient, clean, and economical process for recovering V2O5 from titanium-white waste through hydrogen peroxide stripping and precipitation of vanadium products by heating. Experimental results show that the use of D2EHPA as a modifier prolongs the duration of maximum stripping efficiency, enabling continuous operation.
Article
Metallurgy & Metallurgical Engineering
Guisu Yu, Shuainan Ni, Yun Gao, Ditang Mo, Zhiyuan Zeng, Xiaoqi Sun
Summary: This research proposes a novel green process for the selective recovery of rare earth elements (RE) from spent NdFeB permanent magnet using hydrophobic deep eutectic solvent (HDES). Through optimization of extraction conditions and stripping method, efficient and clean separation and recovery have been achieved.
Article
Metallurgy & Metallurgical Engineering
Jia Li, Xinsheng Wu, Xiaozhou Zhou, Li Zeng, Shengxi Wu, Mingyu Wang, Wenjuan Guan, Zuoying Cao, Qinggang Li, Guiqing Zhang
Summary: This paper presents a complete hydrometallurgical route for the full-component utilization of deep-sea polymetallic nodules (DPN), achieving high recovery efficiency and near-zero waste production with low energy consumption.
Article
Metallurgy & Metallurgical Engineering
Sanae Elmisaoui, Abderrazak M. Latifi, Lhachmi Khamar
Summary: A first principles model is developed to describe the dissolution mechanism of phosphate ore particles in a solution of phosphoric acid. The model accounts for non-uniform size of ore particles using particle size distributions and quantifies their influence on the model predictions. A global estimability analysis is carried out to determine the estimable parameters from experimental data, and the predictions show good agreement with the experimental data. The computed activation energy indicates that diffusion is the rate limiting step of the dissolution process.