The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells

Ca2+-related signaling events influence TLR9-induced IL-10 secretion in human B cells

(2014) Saskia Ziegler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-10: The Master Regulator of Immunity to Infection

(2014) Kevin N. Couper et al.   JOURNAL OF IMMUNOLOGY

Increased CD4+Foxp3+ T Cells in BAFF-Transgenic Mice Suppress T Cell Effector Responses

(2014) S. Walters et al.   JOURNAL OF IMMUNOLOGY

Cytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemia

(2014) D Saulep-Easton et al.   LEUKEMIA

The BAFF/APRIL system: Emerging functions beyond B cell biology and autoimmunity

(2013) Fabien B. Vincent et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Association of serum B cell activating factor from the tumour necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL) with central nervous system and renal disease in systemic lupus erythematosus

(2013) FB Vincent et al.   LUPUS

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Polymorphisms ofTNFandIL-10genes and clinical outcome of patients with chronic lymphocytic leukemia

(2012) Ewa Lech-Maranda et al.   GENES CHROMOSOMES & CANCER

Outcome of patients with relapsed or refractory chronic lymphocytic leukemia treated with flavopiridol: impact of genetic features

(2012) J A Woyach et al.   LEUKEMIA

Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function

(2012) D J DiLillo et al.   LEUKEMIA

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

B regulatory cells in cancer

(2012) Frances Balkwill et al.   TRENDS IN IMMUNOLOGY

Treating chronic lymphocytic leukemia with thalidomide and lenalidomide

(2011) Krzysztof Giannopoulos et al.   EXPERT OPINION ON PHARMACOTHERAPY

Mice Lacking Endogenous IL-10-Producing Regulatory B Cells Develop Exacerbated Disease and Present with an Increased Frequency of Th1/Th17 but a Decrease in Regulatory T Cells

(2011) N. A. Carter et al.   JOURNAL OF IMMUNOLOGY

Soluble BAFF Levels Inversely Correlate with Peripheral B Cell Numbers and the Expression of BAFF Receptors

(2011) M. Kreuzaler et al.   JOURNAL OF IMMUNOLOGY

Phase 1b trial of atacicept, a recombinant protein binding BLyS and APRIL, in patients with chronic lymphocytic leukemia

(2011) D M Kofler et al.   LEUKEMIA

Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL

(2011) J Piñón Hofbauer et al.   LEUKEMIA

Combined analysis of levels of serum B-cell activating factor and a proliferation-inducing ligand as predictor of disease progression in patients with chronic lymphocytic leukemia

(2011) Gerardo Ferrer et al.   LEUKEMIA & LYMPHOMA

Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells

(2010) X. Liang et al.   BLOOD

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

Cutting Edge: Novel Function of B Cell-Activating Factor in the Induction of IL-10-Producing Regulatory B Cells

(2010) M. Yang et al.   JOURNAL OF IMMUNOLOGY

Regulatory B Cells (B10 Cells) and Regulatory T Cells Have Independent Roles in Controlling Experimental Autoimmune Encephalomyelitis Initiation and Late-Phase Immunopathogenesis

(2010) T. Matsushita et al.   JOURNAL OF IMMUNOLOGY

Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease

(2010) Giovanni D’Arena et al.   LEUKEMIA RESEARCH

Atacicept: targeting B cells in multiple sclerosis

(2010) Hans-Peter Hartung et al.   Therapeutic Advances in Neurological Disorders

High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia

(2009) M. Herling et al.   BLOOD

CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis

(2009) J. M. Fletcher et al.   JOURNAL OF IMMUNOLOGY

Enhanced formation and survival of CD4+CD25hiFoxp3+T-cells in chronic lymphocytic leukemia

(2009) Margot Jak et al.   LEUKEMIA & LYMPHOMA

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

(2009) Masako Murai et al.   NATURE IMMUNOLOGY

E -TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction

(2009) G. Gorgun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia

(2008) L. Z. Rassenti et al.   BLOOD

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

(2008) M. Hallek et al.   BLOOD