Article
Genetics & Heredity
Alexandra Peyser, Stephanie Brownridge, Mary Rausch, Nicole Noyes
Summary: Analyzing donor oocyte (DE) data over 6 years revealed that using freshly retrieved eggs (FRESH-EGG) was more effective than purchasing frozen eggs (FROZEN-EGG). Additionally, utilizing the combination of FRESH-EGG and FRESH-ET was superior to newer DE treatment combinations, whereas the use of PGT-A did not improve success rates.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2021)
Article
Genetics & Heredity
Ana Nogueira, Omar Ammar, Enes Bilir, Lavinia Iftene, Ignacio Torrero, Nathan Ceschin, Cristina Nogueira-Silva, Pedro Brandao
Summary: This study evaluates the opinion of university students on the identification or nonidentification of gamete donation and the probability of donation under different regimes. The results show that most respondents are poorly informed about the donation procedure and legislation, prefer nonidentified donation, and are less likely to donate in an open identity regime. Therefore, an identified regime may be less attractive to potential donors and lead to a decrease in the availability of gamete donors.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2023)
Article
Obstetrics & Gynecology
Ermanno Greco, Valeria Donno, Alessia Greco, Maria Giulia Minasi, Andrea Pristera, Giulia Pirastu, Maria Teresa Varricchio, Katarzyna Litwicka, Cristina Arrivi, Cecilia Mencacci, Pierfrancesco Greco
Summary: In addition to the number of available oocytes after warming, male BMI, semen characteristics, and blastocyst transfer are critical factors influencing the reproductive outcomes of egg donation programmes with imported vitrified oocytes.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Obstetrics & Gynecology
Summary: Technology and evolving regulatory framework have led to changes in medical terminology, particularly in describing the relationships between gamete and embryo donors and recipients. The use of social media and DNA testing has made it necessary to move away from terms like "known" and "anonymous" and adopt more accurate terms like "directed" and "nonidentified".
FERTILITY AND STERILITY
(2022)
Article
Engineering, Multidisciplinary
Mariam Hamada, Sameh A. Salem, Fatty M. Salem
Summary: In this paper, a Lightweight Anonymous Mutual Authentication Scheme (LAMAS) based on elliptic curve cryptography is proposed for securing fog computing. The scheme achieves mutual authentication between fog users and servers, even when a fog server is added after user registration. The fog user's identity is hidden and cannot be predicted due to the Elliptic Curve Discrete Logarithm Problem (ECDLP). Formal and informal security analysis is conducted to prove the security of the scheme, and comparisons with related schemes demonstrate its superiority and efficiency in terms of computation cost and storage requirements.
AIN SHAMS ENGINEERING JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Jasmine Grewal, Anne Marie Valente, Alexander C. Egbe, Fred M. Wu, Eric V. Krieger, Virginia P. Sybert, Iris M. van Hagen, Luc M. Beauchesne, Fred H. Rodriguez, Craig S. Broberg, Anitha John, Elisa A. Bradley, Jolien W. Roos-Hesselink
Summary: This study provides insights into pregnancy outcomes in women with Turner syndrome. Pregnancy in women with TS without structural heart disease does not increase the risk of cardiovascular outcomes. For women with TS with structural heart disease, pregnancy may not be as prohibitive as previously thought, but ongoing evaluation is necessary.
Article
Computer Science, Information Systems
Shamim Shihab, Riham Altawy
Summary: The translation discusses the importance of secure communication in remote healthcare monitoring systems and introduces a lightweight mutual authentication protocol, LAPRD. The proposed protocol provides robustness to desynchronization attacks and ensures user and sensor node anonymity. Comparative analysis shows that LAPRD offers higher security with lower computation and communication overheads, making it suitable for practical implementation in lightweight healthcare environments.
IEEE INTERNET OF THINGS JOURNAL
(2023)
Article
Genetics & Heredity
Carolina Lumertz Martello, Marcos Iuri Roos Kulmann, Luiza Mezzomo Donatti, Adriana Bos-Mikich, Nilo Frantz
Summary: The study found that preimplantation genetic testing for aneuploidies (PGT-A) in fresh oocyte donation cycles did not show a significant improvement in clinical outcomes compared to cycles without PGT-A. Despite a slightly higher euploidy rate in the PGT-A group, there was no statistically significant difference in implantation rate between the two groups. Live birth rates also did not differ between the groups.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2021)
Article
Ethics
Femke Takes
Summary: The past acceptance of concealing the truth about a child's biological origin has given way to the prevalent belief in sharing this information with the child in the past two decades, signifying a significant shift in the notion of the child's best interest. Analyzing this changed notion using a framework encompassing three views of the child derived from the debate on children's rights can lead to a better understanding of this evolution.
Article
Family Studies
Rafal Lukasiewicz, Sonia Allan
Summary: This article examines donor-matching in medically assisted reproduction, including the methods used, reasons for its use, and laws and practices across different European jurisdictions. The discussion also considers the potential impact of donor-matching on individuals born through third-party reproduction.
INTERNATIONAL JOURNAL OF LAW POLICY AND THE FAMILY
(2022)
Article
Business
Malika Malika, Durairaj Maheswaran, Shailendra Pratap Jain
Summary: Financial constraints influence consumer preferences for solitary or social purchases, with independent consumers preferring solitary purchases and interdependent consumers preferring social purchases. Self-construal moderates how consumers spend discretionary income, showing that communal norms play a role in mediating the preference for social purchases among interdependent consumers, while salient communal norms can change the preference for solitary purchases among independent consumers.
JOURNAL OF THE ACADEMY OF MARKETING SCIENCE
(2022)
Article
Obstetrics & Gynecology
Marc Torra-Massana, Irene Miguel-Escalada, Rita Vassena, Amelia Rodriguez
Summary: This retrospective cohort study examined the effects of long-term storage of vitrified oocytes on laboratory and reproductive outcomes. The results showed that the storage time did not significantly impact oocyte survival, fertilization rate, pregnancy, and live birth rates.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Obstetrics & Gynecology
Abigail Combs, Mariah J. Kimes, Carolyn R. Jaslow, Heidi Hayes, Lindsey B. O'Leary, Michael J. Levy, William H. Kutteh
Summary: This study investigated the relationship between oocyte donor characteristics and their perception, expectation, and experience of pain, as well as the interaction between pain and overall satisfaction with the donation process. The results showed that most donors rated their pain as minimal to moderate. Altruistically motivated and parous donors were less likely to experience unexpected levels of pain. The majority of donors reported being informed of the risk of pain. Unexpected levels of pain were highly related to low donor satisfaction.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Obstetrics & Gynecology
Vanessa Pataia, Shailaja Nair, Marta Wolska, Elena Linara-Demakakou, Trina Shah, Giuseppina Lamanna, Nick Macklon, Kamal K. Ahuja
Summary: Donor age and AMH are independent predictors of oocyte yield, while recipient BMI and history of miscarriages impact cumulative live birth rates. Selecting donors aged 23-29 years may increase live birth rates in recipients.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Article
Sociology
Irina G. Polyakova, Dmitry O. Mazurov, Elvira E. Symanyuk, Aleksandra Yu. Khramtsova
Summary: The study examines the motivations of Russian oocyte donors and the social and cultural factors that influence these motivations. Findings reveal that most oocyte donors in Russia are married women aged 26, with low income, and at least one child. Their motivations include financial rewards, altruism, and helping friends or relatives struggling with infertility. Interestingly, many donors see their decision to donate as a way to overcome past trauma and achieve personal fulfillment. Anonymity is a significant barrier to donation, as donors are unwilling to disclose their identity due to concerns about controversy, privacy, and negative public attitudes.
CHANGING SOCIETIES & PERSONALITIES
(2022)
Article
Obstetrics & Gynecology
M. Condorelli, M. De Vos, S. Lie Fong, C. Autin, A. Delvigne, F. Vanden Meerschaut, C. Wyns, R. Imbert, C. Cheruy, J. Bouziotis, E. de Azambuja, A. Delbaere, M. Lambertini, I Demeestere
Summary: The risk of recurrence in young breast cancer survivors who undergo assisted reproductive technologies (ARTs) following completion of anticancer treatment does not appear to be increased, as shown by previous studies. More research is needed to confirm the safety of ART in this population.
HUMAN REPRODUCTION
(2021)
Article
Obstetrics & Gynecology
Thu Yen Thi Nguyen, Luciana Cacciottola, Alessandra Camboni, Joachim Ravau, Michel De Vos, Isabelle Demeestere, Jacques Donnez, Marie-Madeleine Dolmans
Summary: The study did not detect malignancy reseeding in cryopreserved ovarian tissue from 20 patients with CNS tumors, indicating a lack of tumor seeding in frozen-thawed and xenografted tissue.
HUMAN REPRODUCTION
(2021)
Article
Oncology
Richard A. Anderson, Florian Clatot, Isabelle Demeestere, Matteo Lambertini, Adrienne Morgan, Scott M. Nelson, Fedro Peccatori, David Cameron
Summary: Cancer treatment can have adverse effects on reproductive function, leading to loss of fertility, sexual desire and function, and hormone deficiency. Proactive assessment and counseling on the impact of treatment on reproductive function are essential for patient mental health and quality of life. Providing accurate information and fertility preservation options can potentially influence treatment decisions and improve patient outcomes.
EUROPEAN JOURNAL OF CANCER
(2021)
Article
Oncology
Volkan Turan, Matteo Lambertini, Dong-Yun Lee, Erica Wang, Florian Clatot, Beth Y. Karlan, Isabelle Demeestere, Heejung Bang, Kutluk Oktay
Summary: The study found that young women with germline BRCA pathogenic variants, especially those affected and with BRCA1, have lower serum AMH levels compared to controls. This suggests they may need more counseling regarding the possibility of a shortened reproductive lifespan due to diminished ovarian reserve.
JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Oncology
Isabelle Demeestere, Judith Racape, Julie Dechene, Jehan Dupuis, Franck Morschhauser, Virginie De Wilde, Julien Lazarovici, Herve Ghesquieres, Mohamed Touati, David Sibon, Magda Alexis, Anne-Claire Gac, Hannah Moatti, Emmanuelle Virelizier, Herve Maisonneuve, Delphine Pranger, Roch Houot, Luc-Matthieu Fornecker, Adrian Tempescul, Marc Andre, Rene-Olivier Casasnovas
Summary: The PET-driven strategy significantly reduced the risk of gonadal dysfunction and infertility in patients with advanced Hodgkin lymphoma, particularly in terms of reducing premature ovarian insufficiency and low ovarian reserve. Men in the PET-driven group had better recovery of sperm parameters after treatment compared to the standard therapy group, with a lower risk of severe testicular damage and a higher likelihood of achieving pregnancy.
JOURNAL OF CLINICAL ONCOLOGY
(2021)
Review
Oncology
Matteo Lambertini, Eva Blondeaux, Marco Bruzzone, Marta Perachino, Richard A. Anderson, Evandro de Azambuja, Philip D. Poorvu, Hee Jeong Kim, Cynthia Villarreal-Garza, Barbara Pistilli, Ines Vaz-Luis, Cristina Saura, Kathryn J. Ruddy, Maria Alice Franzoi, Chiara Sertoli, Marcello Ceppi, Hatem A. Azim, Frederic Amant, Isabelle Demeestere, Lucia Del Mastro, Ann H. Partridge, Olivia Pagani, Fedro A. Peccatori
Summary: This study found that breast cancer survivors are less likely to have a subsequent pregnancy compared to the general population, and they face higher risks during pregnancy, especially among those who have received chemotherapy. However, compared to breast cancer patients without subsequent pregnancy, those who become pregnant have better disease-free survival and overall survival rates.
JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Oncology
Francoise Rothe, Matteo Lambertini, Oranite Goldrat, Marion Maetens, Yacine Bareche, Jeremy Blanc, Ghizlane Rouas, Denis Larsimont, Christos Sotiriou, Michail Ignatiadis, Isabelle Demeestere
Summary: The study assessed the safety of using let-COS in breast cancer patients for fertility preservation by analyzing ctDNA levels. Results showed that 93% of patients did not experience an increase in ctDNA levels after receiving let-COS, indicating its safety and efficacy for young women with early breast cancer interested in fertility preservation.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Margherita Condorelli, Maelle Sens, Oranite Goldrat, Anne Delbaere, Judith Racape, Matteo Lambertini, Isabelle Demeestere
Summary: This study suggests that scattered ionizing radiation from staging assessment during ovarian stimulation for fertility preservation in breast cancer patients appears to be safe and does not compromise oocyte quality.
BREAST CANCER RESEARCH AND TREATMENT
(2022)
Article
Obstetrics & Gynecology
K. Kteily, D. Pening, P. Diaz Vidal, M. Devos, J. Dechene, A. Op de Beeck, A. Botteaux, S. Janssens, E. Van den Abbeel, O. Goldrat, A. Delbaere, I Demeestere
Summary: The study found that SARS-CoV-2 mRNA is not detectable in the reproductive tract of asymptomatic patients undergoing ART, regardless of the results from a triage questionnaire and a nasopharyngeal SARS-CoV-2 RNA detection test.
HUMAN REPRODUCTION
(2022)
Article
Oncology
M. Condorelli, M. Bruzzone, M. Ceppi, A. Ferrari, A. Grinshpun, A. S. Hamy, E. de Azambuja, E. Carrasco, F. A. Peccatori, A. Di Meglio, S. Paluch-Shimon, P. D. Poorvu, M. Venturelli, C. Rousset-Jablonski, C. Senechal, L. Livraghi, R. Ponzone, L. De Marchis, K. Pogoda, A. Sonnenblick, C. Villarreal-Garza, O. Cordoba, L. Teixeira, F. Clatot, K. Punie, R. Graffeo, M. Dieci, J. A. Perez-Fidalgo, F. P. Duhoux, F. Puglisi, A. R. Ferreira, E. Blondeaux, T. Peretz-Yablonski, O. Caron, C. Saule, L. Ameye, J. Balmana, A. H. Partridge, H. A. Azim, I Demeestere, M. Lambertini
Summary: In breast cancer survivors carrying germline BRCA1/2 pathogenic variants, assisted reproductive techniques (ART) may be a safe option when natural conception fails. Patients in the ART group were older and experienced more delivery complications, but there were no apparent differences in other obstetrical outcomes between the two groups.
Letter
Obstetrics & Gynecology
I Demeestere, E. van den Abbeel, A. Delbaere
HUMAN REPRODUCTION
(2022)
Review
Obstetrics & Gynecology
Hajra Khattak, Rosamund Malhas, Laurentiu Craciunas, Yousri Afifi, Christiani A. Amorim, Simon Fishel, Sherman Silber, Debra Gook, Isabelle Demeestere, Olga Bystrova, Alla Lisyanskaya, Georgy Manikhas, Laura Lotz, Ralf Dittrich, Lotte Berdiin Colmorn, Kirsten Tryde Macklon, Ina Marie Dueholm Hjorth, Stine Gry Kristensen, Ioannis Gallos, Arri Coomarasamy
Summary: Ovarian tissue cryopreservation and transplantation techniques have evolved over the past two decades with the aim of restoring fertility and hormonal function in women. Although evidence of success is largely based on case reports, studies demonstrate that this technology can restore reproductive and hormonal functions in women.
HUMAN REPRODUCTION UPDATE
(2022)
Correction
Obstetrics & Gynecology
Hajra Khattak, Rosamund Malhas, Laurentiu Craciunas, Yousri Afifi, Christiani A. Amorim, Simon Fishel, Sherman Silber, Debra Gook, Isabelle Demeestere, Olga Bystrova, Alla Lisyanskaya, Georgy Manikhas, Laura Lotz, Ralf Dittrich, Lotte Berdiin Colmorn, Kirsten Tryde Macklon, Ina Marie Dueholm Hjorth, Stine Gry Kristensen, Ioannis Gallos, Arri Coomarasamy
HUMAN REPRODUCTION UPDATE
(2022)
Article
Obstetrics & Gynecology
Melody Devos, Paula Diaz Vidal, Jason Bouziotis, Ellen Anckaert, Marie-Madeleine Dolmans, Isabelle Demeestere
Summary: Chemotherapy exposure prior to ovarian tissue cryopreservation increases follicle apoptosis rates but not follicular activation. The PI3K/AKT/mTOR and Hippo signaling pathways are modified in the cortex. However, the consequences of treatment on follicle activation and survival require further investigation.
HUMAN REPRODUCTION
(2023)
Article
Oncology
Renee L. Mulder, Anna Font-Gonzalez, Melissa M. Hudson, Hanneke M. van Santen, Erik A. H. Loeffen, Karen C. Burns, Gwendolyn P. Quinn, Eline van Dulmen-den Broeder, Julianne Byrne, Riccardo Haupt, W. Hamish Wallace, Marry M. van den Heuvel-Eibrink, Antoinette Anazodo, Richard A. Anderson, Anke Barnbrock, Joern D. Beck, Annelies M. E. Bos, Isabelle Demeestere, Christian Denzer, Natascia Di Iorgi, Holly R. Hoefgen, Rejin Kebudi, Cornelis Lambalk, Thorsten Langer, Lillian R. Meacham, Kenny Rodriguez-Wallberg, Catharyn Stern, Eveline Stutz-Grunder, Wendy van Dorp, Margreet Veening, Saskia Veldkamp, Eline van der Meulen, Louis S. Constine, Lisa B. Kenney, Marianne D. van de Wetering, Leontien C. M. Kremer, Jennifer Levine, Wim J. E. Tissing
Summary: This study aims to develop clinical practice guidelines for fertility preservation in female patients diagnosed with childhood, adolescent, and young adult cancer at age 25 years or younger. By utilizing the Grading of Recommendations Assessment, Development and Evaluation methodology, transparent recommendations were formed to facilitate the care of high-risk female patients. Collaboration led to a comprehensive review of existing evidence, transparent reporting, and achievement of global interdisciplinary consensus.