Article
Public, Environmental & Occupational Health
Yael I. Nillni, Holly M. Crowe, Jennifer J. Yland, Amelia K. Wesselink, Lauren A. Wise
Summary: This study aimed to examine the association between time-to-pregnancy (TTP) and postpartum depression (PPD), and determine whether perceived stress during early pregnancy mediated this association. The results indicated a modest positive dose-response association between delayed conception and PPD, with early pregnancy perceived stress explaining only a small proportion of this association.
ANNALS OF EPIDEMIOLOGY
(2022)
Article
Obstetrics & Gynecology
Lihua Huang, See Ling Loy, Wei-Qing Chen, Johan G. Eriksson, Yap Seng Chong, Zhongwei Huang, Jerry Kok Yen Chan, Tien Yin Wong, Michael Kramer, Cuilin Zhang, Ling-Jun Li
Summary: Abnormalities in retinal microvasculature during the pre-conception phase were found to be temporarily associated with a prolonged time-to-pregnancy in this prospective study, indicating that suboptimal microcirculation may lead to reduced female fecundability.
HUMAN REPRODUCTION
(2021)
Article
Obstetrics & Gynecology
Holly Michelle Crowe, Amelia Kent Wesselink, Lauren Anne Wise, Tanran R. Wang, Charles Robert Horsburgh, Ellen Margrethe Mikkelsen, Elizabeth Elliott Hatch
Summary: The study evaluated the association between female preconception antibiotic use and fecundability among a cohort of pregnancy planners. Overall, preconception antibiotic use was not significantly associated with fecundability, with certain types of antibiotics showing slightly increased or decreased fecundability.
HUMAN REPRODUCTION
(2021)
Article
Medicine, General & Internal
Xiang Hong, Jun Zhao, Jiechen Yin, Fanqi Zhao, Wei Wang, Xiaoling Ding, Hong Yu, Xu Ma, Bei Wang
Summary: This study found an association between the pre-pregnancy vaginal microbiome and female fecundability. The microbial community structures in the vaginal samples of pregnant and non-pregnant women were significantly different, with higher abundance of Lactobacillus in the pregnancy group and higher abundance of Gardnerella in the non-pregnant group. The study also revealed that higher abundance of Lactobacillus gasseri was associated with increased fecundability, while higher abundance of Fannyhessea vaginae was associated with decreased fecundability.
Article
Obstetrics & Gynecology
S. L. Mumford, K. S. Flannagan, J. G. Radoc, L. A. Sjaarda, J. R. Zolton, T. D. Metz, T. C. Plowden, N. J. Perkins, E. A. De Vilbiss, V. C. Andriessen, A. C. Purdue-Smithe, K. Kim, S. F. Yisahak, J. R. Freeman, Z. Alkhalaf, R. M. Silver, E. F. Schisterman
Summary: The study found that preconception cannabis use was associated with reduced fecundability among women with a history of pregnancy loss, despite an increased frequency of intercourse.
HUMAN REPRODUCTION
(2021)
Article
Clinical Neurology
Mia Charifson, Akhgar Ghassabian, Eunsil Seok, Mrudula Naidu, Shilpi S. Mehta-Lee, Sara G. Brubaker, Yelena Afanasyeva, Yu Chen, Mengling Liu, Leonardo Trasande, Linda G. Kahn
Summary: This study investigates the associations between nighttime sleep characteristics and time to pregnancy. The results suggest that both sleep duration and sleep midpoint may have an impact on fecundability, and this association is influenced by chronotype.
Article
Public, Environmental & Occupational Health
Sydney K. Willis, Elizabeth E. Hatch, Amelia K. Wesselink, Kenneth J. Rothman, Ellen M. Mikkelsen, Katherine A. Ahrens, Lauren A. Wise
Summary: The study found that long post-partum intervals (>= 48 months) were associated with slightly reduced fecundability, while short post-partum intervals (<12 months) were weakly associated with reduced fecundability in some subgroups.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Alyssa F. Harlow, Elizabeth E. Hatch, Amelia K. Wesselink, Kenneth J. Rothman, Lauren A. Wise
Summary: Current use of e-cigarettes is associated with slightly lower fecundability, but the independent and joint associations with combustible cigarette smoking are inconsistent and imprecise.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Obstetrics & Gynecology
Xiaona Huo, Lin Zhang, Rong Huang, Jiangfeng Ye, Yulin Yang, Hao Zhang, Jun Zhang
Summary: The study found that halitosis is associated with reduced fecundability in Chinese women.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Obstetrics & Gynecology
Erica M. Lokken, Emmanuel Kabare, Brenda Oyaro, Maureen Nyaigero, John Kinuthia, Walter Jaoko, Kishor Mandaliya, R. Scott Mcclelland, Lisa E. Manhart
Summary: Preconception Mycoplasma genitalium-infection was associated with reduced fecundability, although the association may depend on concurrent bacterial vaginosis (BV).
HUMAN REPRODUCTION
(2023)
Article
Obstetrics & Gynecology
Ellen Margrethe Mikkelsen, Sinna Pilgaard Ulrichsen, Benjamin Randeris Johannesen, Anne Sofie Dam Laursen, Lauren Anne Wise, Elizabeth Elliott Hatch, Kenneth Jay Rothman, Amelia Kent Wesselink, Holly Crowe, Henrik Toft Sorensen
Summary: This study assessed the association between preconception antibiotic use and fecundability. The results showed that the use of antibiotics, especially sulfonamides and macrolides, was associated with decreased fecundability.
FERTILITY AND STERILITY
(2023)
Article
Obstetrics & Gynecology
X. Hong, J. Zhao, X. Zhu, Q. Dai, H. Zhang, Y. Xuan, J. Yin, Yue Zhang, X. Yang, S. Fang, Q. Wang, H. Shen, Yiping Zhang, D. Yan, Y. Wang, Z. Peng, Ya Zhang, B. Wang, X. Ma
Summary: This study found a negative association between a poor vaginal microenvironment and women's fecundability, emphasizing the importance of assessing vaginal health during pre-pregnancy check-ups. Women with a poor vaginal microenvironment were associated with a reduction in fecundability.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Erica M. Lokken, Anne Pulei, Brenda Oyaro, Maureen Nyaigero, Walter Jaoko, Kishor Mandaliya, John Kinuthia, R. Scott McClelland
Summary: This study found an association between vaginal washing and reduced fecundability among Kenyan women. Vaginal washing may alter the vaginal microbiota, cause inflammation, disrupt cervical mucus, and affect sperm function. Ceasing vaginal washing may improve women's chances of conceiving.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Anne Marie Z. Jukic, Clarice R. Weinberg, Sunni L. Mumford, Anne Z. Steiner
Summary: This study aimed to investigate the association between inflammation and fecundability. The results showed no significant association between C-reactive protein (CRP) and fecundability, both overall and within different levels of BMI.
Article
Obstetrics & Gynecology
See Ling Loy, Chee Wai Ku, Yin Bun Cheung, Keith M. Godfrey, Yap-Seng Chong, Lynette Pei-Chi Shek, Kok Hian Tan, Fabian Kok Peng Yap, Jonathan Y. Bernard, Helen Chen, Shiao-Yng Chan, Tse Yeun Tan, Jerry Kok Yen Chan
Summary: Research on preconception Asian women found that low FSF is associated with longer time-to-pregnancy. Factors like physical activity, obesity, absence of depression and anxiety are related to decreased odds of low FSF and higher FSFI-6 scores.
BMC PREGNANCY AND CHILDBIRTH
(2021)