What next for preimplantation genetic screening? High mitotic chromosome instability rate provides the biological basis for the low success rate

Chromosome instability is common in human cleavage-stage embryos

(2009) Evelyne Vanneste et al.   NATURE MEDICINE

Preimplantation aneuploidy testing for infertile patients of advanced maternal age: a randomized prospective trial

(2008) William B. Schoolcraft et al.   FERTILITY AND STERILITY

What next for preimplantation genetic screening? Randomized clinical trial in assessing PGS: necessary but not sufficient

(2008) J. L. Simpson   HUMAN REPRODUCTION

ESHRE PGD Consortium data collection VIII: cycles from January to December 2005 with pregnancy follow-up to October 2006

(2008) V. Goossens et al.   HUMAN REPRODUCTION

No beneficial effect of preimplantation genetic screening in women of advanced maternal age with a high risk for embryonic aneuploidy

(2008) M. Twisk et al.   HUMAN REPRODUCTION

Preimplantation genetic screening does not improve delivery rate in women under the age of 36 following single-embryo transfer

(2008) C. Staessen et al.   HUMAN REPRODUCTION

Preimplantation genetic screening: the end of an affair?

(2008) B. C.J.M. Fauser   HUMAN REPRODUCTION

What next for preimplantation genetic screening? More randomized controlled trials needed?

(2008) S. Mastenbroek et al.   HUMAN REPRODUCTION

Preimplantation genetic screening in women of advanced maternal age caused a decrease in clinical pregnancy rate: a randomized controlled trial

(2008) T. Hardarson et al.   HUMAN REPRODUCTION

What next for preimplantation genetic screening?

(2008) J. Harper et al.   HUMAN REPRODUCTION