Article
Psychiatry
David Kimhy, Luz H. Ospina, Katie Beck-Felts, Amanda Lister, Coral Omene, Galen Bodenhausen, Vijay Mittal
Summary: This study explores the potential links between psychiatric and affective indicators and negative racial attitudes (NRA). The results indicate that difficulties in identifying and describing emotions, use of suppression to regulate emotions, and perceptual abnormalities are significantly correlated with explicit and covert NRA. Moreover, these affective and psychiatric indicators explain 5.2% and 10.4% of the variance in explicit and covert NRA, respectively.
PSYCHIATRY RESEARCH
(2023)
Article
Pediatrics
Andreas Goreis, Bettina Pfeffer, Heidi Elisabeth Zesch, Diana Klinger, Tamara Reiner, Mercedes M. M. Bock, Susanne Ohmann, Petra Sackl-Pammer, Sonja Werneck-Rohrer, Harald Eder, Katrin Skala, Klara Czernin, Dunja Mairhofer, Bernhard Rohringer, Carolin Bedus, Ronja Lipp, Christine Vesely, Paul L. L. Plener, Oswald D. D. Kothgassner
Summary: This study examined the association between conspiracy beliefs and guideline adherence among adolescents with mental health problems. The findings showed that although a small percentage of the sample endorsed COVID-19 conspiracy theories, most adolescents demonstrated good adherence to public health measures despite experiencing mental distress. Adverse childhood experiences and peer/conduct problems were identified as important predictors of conspiracy beliefs.
CHILD AND ADOLESCENT PSYCHIATRY AND MENTAL HEALTH
(2023)
Article
Psychiatry
Laszlo Pogany, Judit Lazary
Summary: Research has shown that there are differences in attitudes towards drug treatment between psychiatric and non-psychiatric patients, with addicts and psychiatric patients scoring higher in health locus of control and psychological reactance. Additionally, psychiatric patients exhibited a more pronounced mistrust in physicians compared to non-psychiatric patients.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Paola Bozzatello, Benedetta Giordano, Cristiana Montemagni, Paola Rocca, Silvio Bellino
Summary: This study found that besides psychopathology and severity of the disease, several clinical, socio-demographic, and illness-related variables also predicted improvement of real-world functioning.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Psychology, Clinical
Shin Tae Kim, Jun Ho Seo, Sangmin Lee, Sumoa Jeon, Chun Il Park, Se Joo Kim, Jee In Kang
Summary: This study examined dysfunctional coronavirus anxiety in nonpsychotic psychiatric outpatients during the pandemic and found that health worry may be an important bridge symptom that connects coronavirus anxiety and other clinical psychopathology.
DEPRESSION AND ANXIETY
(2022)
Article
Psychiatry
Minhua Chen, Lina Zhou, Li Ye, Gelin Lin, Yongli Pang, Liyun Lu, Xianglan Wang
Summary: This study investigated the initial adherence and relevant factors among psychiatric outpatients. The results showed that factors such as work, family atmosphere, attitudes towards medication, personality characteristics, and mental status were related to initial adherence.
Article
Pharmacology & Pharmacy
Carina Lundby, Marianne Nielsen, Trine Simonsen, Stine Galsgaard, Maija Bruun Haastrup, Lene Vestergaard Ravn-Nielsen, Anton Pottegard
Summary: Understanding the attitudes and perspectives of older psychiatric patients towards deprescribing is crucial for promoting patient-centered care. This study found that half of the patients had an intrinsic desire to stop taking medication, while the majority were willing to do so on their physician's advice. Concerns about missing out on future benefits and previous negative experiences with deprescribing were also significant factors influencing patient attitudes.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
(2023)
Article
History & Philosophy Of Science
Jonathan Mitchell
Summary: This paper argues that affective experiences involve a type of personal-level affective representation that is non-transparent and non-sensory, representing the object of the experience as minimally good or bad, and having the power to motivate relevant attitudes.
Article
Multidisciplinary Sciences
Lisa Kertzscher, Sabrina Baldofski, Elisabeth Kohls, Georg Schomerus, Christine Rummel-Kluge
Summary: This study highlights the importance of maintaining stable medical care provision for people with mental disorders during the COVID-19 pandemic. Despite a decrease in resilience, mental health status remains stable.
Article
Psychiatry
Paolo Valsecchi, Gabriele Nibbio, Jennifer Rosa, Antonio Vita
Summary: Sleep disorders are more frequent and severe in subjects diagnosed with ADHD compared to other adult outpatients. Sleep disturbances might represent an intrinsic feature in adult ADHD subjects, presenting important clinical repercussions, and should be routinely evaluated and monitored in this population.
PSYCHIATRY RESEARCH
(2022)
Article
Medicine, General & Internal
Yoshinori Sasaki, Masahide Usami, Shoko Sasaki, Hikaru Sunakawa, Yusuke Toguchi, Shuichi Tanese, Kiyoshi Saito, Rena Shinohara, Toshinari Kurokouchi, Kaori Sugimoto, Yuki Hakoshima, Kumi Inazaki, Yuta Yoshimura, Yuki Mizumoto, Takayuki Okada
Summary: This study aimed to evaluate the clinical characteristics of child and adolescent psychiatric patients with child-to-parent violence (CPV). The results showed that patients in the CPV group had significantly higher proportions of experiencing physical abuse, psychological abuse, and witnessing violence between parents. Additionally, there was a significant correlation between neurodevelopmental disorders and CPV, with impulsivity potentially being related to CPV.
Article
Psychiatry
Johanna-Marie Zeibig, Britta Seiffer, Gorden Sudeck, Inka Roesel, Martin Hautzinger, Sebastian Wolf
Summary: The 12-week group exercise intervention significantly improved global symptom severity, depression, anxiety, and sleep quality, as well as increased the amount of exercise among a mixed outpatient sample with various psychiatric disorders. The reduction of global symptom severity was significantly predicted by an increase of exercise across both groups.
Article
Psychology, Multidisciplinary
Richard J. Stevenson, Brayson J. Hill, Alannah Hughes, Madeline Wright, Johanna Bartlett, Supreet Saluja, Heather M. Francis
Summary: This study examines the individual differences in interoceptive hunger and its relationship with dysfunctional eating and beliefs about the causes of hunger. The findings suggest that interoceptive hunger is multidimensional and idiosyncratic, with 11 dimensions identified. The study also reveals the reliability of hunger reports and the significant associations between variability in hunger interoception, dysfunctional eating, and hunger beliefs.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Psychiatry
Jiayi Wang, Enzhao Zhu, Pu Ai, Jun Liu, Zhihao Chen, Feng Wang, Fazhan Chen, Zisheng Ai
Summary: This study conducted wide and comprehensive analyses on the use of three scales in Chinese outpatient psychiatric clinics, finding that univariate subscale scores did not have statistical significance among the four diagnostic groups, highlighting the limitations of their practical use in identifying different mental diseases in Chinese outpatient psychiatric services.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Neurosciences
Francesco Pisani, Laura Rosa Pisani, Maria Antonietta Barbieri, Jose de Leon, Edoardo Spina
Summary: Psychiatric disorders often coexist with epilepsy, suggesting common pathological pathways. Some antiseizure medications have mood-stabilising or anxiolytic effects, but others may contribute to psychiatric disorders. Careful evaluation of medication interactions and patient adherence is necessary for optimizing therapy.
CURRENT NEUROPHARMACOLOGY
(2023)
Review
Pharmacology & Pharmacy
Jose de Leon, Georgios Schoretsanitis, Robert L. Smith, Espen Molden, Anssi Solismaa, Niko Seppala, Miloslav Kopecek, Patrik Svancer, Ismael Olmos, Carina Ricciardi, Celso Iglesias-Garcia, Ana Iglesias-Alonso, Edoardo Spina, Can-Jun Ruan, Chuan-Yue Wang, Gang Wang, Yi-Lang Tang, Shih-Ku Lin, Hsien-Yuan Lane, Yong Sik Kim, Se Hyun Kim, Anto P. Rajkumar, Dinora F. Gonzalez-Esquivel, Helgi Jung-Cook, Trino Baptista, Christopher Rohde, Jimmi Nielsen, Helene Verdoux, Clelia Quiles, Emilio J. Sanz, Carlos De las Cuevas, Dan Cohen, Peter F. J. Schulte, Aygun Ertugrul, Nitin Chopra, Betsy McCollum, Charles Shelton, Robert O. Cotes, Arun R. Kaithi, John M. Kane, Saeed Farooq, Chee H. Ng, John Bilbily, Christoph Hiemke, Carlos Lopez-Jaramillo, Ian McGrane, Fernando Lana, Chin B. Eap, Manuel Arrojo-Romero, Erich Seifritz, Susanna Every-Palmer, Chad A. Bousman, Emmanuel Bebawi, Rahul Bhattacharya, Deanna L. Kelly, Yuji Otsuka, Judit Lazary, Rafael Torres, Agustin Yecora, Mariano Motuca, Sherry K. W. Chan, Monica Zolezzi, Sami Ouanes, Domenico De Berardis, Sandeep Grover, Ric M. Procyshyn, Richard A. Adebayo, Oleg O. Kirilochev, Andrey Soloviev, Konstantinos N. Fountoulakis, Alina Wilkowska, Muhammad Ayub, Alzira Silva, Raphael M. Bonelli, Jose M. Villagran-Moreno, Benedicto Crespo-Facorro, Henk Temmingh, Eric Decloedt, Maria R. Pedro, Hiroyoshi Takeuchi, Masaru Tsukahara, Gerhard Gruender, Marina Sagud, Andreja Celofiga, Dragana Ignjatovic Ristic, Bruno B. Ortiz, Helio Elkis, Antonio J. Pacheco Palha, Adrian LLerena, Emilio Fernandez-Egea, Dan Siskind, Abraham Weizman, Rim Masmoudi, Shamin Mohd Saffian, Jonathan G. Leung, Peter F. Buckley, Stephen R. Marder, Leslie Citrome, Oliver Freudenreich, Christoph U. Correll, Daniel J. Muller, A. Elif Anil Yagcioglu, Flavian S. Radulescu, Wieslaw J. Cubala
Summary: This international guideline suggests improving clozapine package inserts globally by utilizing ancestry-based dosing and gradual titration to prevent potential toxicity and ADRs. It defines six personalized titration schedules for different populations and recommends monitoring inflammation globally.
PHARMACOPSYCHIATRY
(2022)
Review
Pharmacology & Pharmacy
Carlos De las Cuevas, Emilio J. Sanz, Christopher Rohde, Jose de Leon
Summary: This review examines the association between antipsychotics (other than clozapine) and myocarditis through literature analysis and data from VigiBase. Quetiapine and olanzapine were found to have a significant statistical signal for myocarditis, with a high percentage of cases also involving co-prescription of clozapine. Further research is needed to investigate cases of myocarditis caused by antipsychotics during overdose or titration.
EXPERT REVIEW OF CLINICAL PHARMACOLOGY
(2022)
Article
Health Care Sciences & Services
Carlos de las Cuevas, Luis Gutierrez-Rojas, Miguel A. Alvarez-Mon, Alvaro Andreu-Bernabeu, Luis Capitan, Juan Carlos Gomez, Iria Grande, Diego Hidalgo-Mazzei, Raimundo Mateos, Pedro Moreno-Gea, Tomas De Vicente-Munoz, Francisco Ferre
Summary: The study showed that an online educational intervention significantly improved psychiatrists' awareness, knowledge and attitudes toward telepsychiatry, but did not have a significant impact on their skills.
TELEMEDICINE AND E-HEALTH
(2023)
Article
Environmental Sciences
Mariela Loreto Lara-Cabrera, Moises Betancort, Amparo Munoz-Rubilar, Natalia Rodriguez-Novo, Ottar Bjerkeset, Carlos De las Cuevas
Summary: This study aimed to validate the WHO-5 Well-Being Index in a sample of nurses. The results showed that the scale demonstrated good reliability and validity in three countries and can be used to measure nurses' well-being during a pandemic.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Pharmacology & Pharmacy
Michiel J. J. Bakkum, Petra Verdonk, Elias G. G. Thomas, Floor van Rosse, Michael Okorie, Paraskevi Papaioannidou, Robert Likic, Emilio J. J. Sanz, Thierry Christiaens, Joao N. Costa, Lorena Dima, Fabrizio de Ponti, Jeroen van Smeden, Michiel A. A. van Agtmael, Milan C. C. Richir, Jelle Tichelaar
Summary: The relationship between race and biology is complex, and while race is used as a variable in medical guidelines, it has no biological essence. Many teachers unintentionally medicalize race, causing students to misunderstand racial differences. The relation between race and health is easily biased by factors such as stereotypes and other influences. Clinical case vignettes used in teaching often lack diversity and contain biases.
CLINICAL PHARMACOLOGY & THERAPEUTICS
(2023)
Review
Biochemistry & Molecular Biology
Carlos De las Cuevas, Emilio J. Sanz, Jose de Leon
Summary: This study reviewed respiratory aspiration events associated with benzodiazepines, AEDs, and/or ADs, and considered the confounding effects of polypharmacy. The results showed that respiratory aspiration events related to these three drug classes were associated with drug overdose, polypharmacy, and/or major medical problems.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY
(2022)
Article
Pharmacology & Pharmacy
Michiel J. Bakkum, Erik M. Donker, Pietro Spitaleri Timpone, Charlotte A. M. Hagen, Milan C. Richir, Michiel A. van Agtmael, Fabrizio De Ponti, Jelle Tichelaar
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Carlos De Las Cuevas, Emilio J. Sanz, Alejandro G. Villasante-Tezanos, Jose de Leon
Summary: Respiratory aspiration may be associated with antipsychotic (AP) treatment or overdose. Cases of respiratory aspiration were reported during clozapine therapy and AP overdose. The information components (ICs) for APs, clozapine, quetiapine, and olanzapine were relatively high. Respiratory aspiration cases associated with APs included overdose/suicide cases and cases during treatment, with a high fatality rate among patients taking clozapine. Multiple mechanisms of action of APs may contribute to respiratory aspiration.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY
(2023)
Article
Pharmacology & Pharmacy
Jose de Leon, Manuel Arrojo-Romero, Helene Verdoux, Can-Jun Ruan, Georgios Schoretsanitis, Christopher Rohde, Dan Cohen, Peter F. J. Schulte, Se Hyun Kim, Robert O. Cotes, Jonathan G. Leung, Yuji Otsuka, Oleg O. Kirilochev, Trino Baptista, Sandeep Grover, Susanna Every-Palmer, Scott R. Clark, Ian R. McGrane, Mariano Motuca, Ismael Olmos, Alina Wilkowska, Marina Sagud, A. Elif Anil Yagcioglu, Dragana Ignjatovic Ristic, Judit Lazary, Emilio J. Sanz, Carlos de Las Cuevas
Summary: This article discusses the global outcomes of clozapine usage and finds an uneven distribution of fatal outcomes in different countries, which may be related to the frequency of adverse reactions to clozapine. Studies from Finland and Denmark did not find increased mortality or clear evidence of clozapine toxicity. Case data from the UK show a high proportion of clozapine-associated fatal outcomes globally.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
(2023)
Article
Health Care Sciences & Services
Pablo A. Marrero-Morales, Enrique Gonzalez-Davila, Maria Fernanda Hernandez-Gutierrez, Eva M. Gallego-Gonzalez, Martina Jimenez-Hernandez, Emilio J. Sanz-Alvarez, Natalia Rodriguez-Novo, Yurena M. Rodriguez-Novo
Summary: This study aimed to evaluate the functional status of patients one year after hip fracture surgery and the influence of sarcopenia and other clinical factors at the time of admission. The study found that gender, risk of sarcopenia, cognitive impairment, and functional status at admission were related to the functional status at one year. Knowing the estimated functional status at one year can aid in individualized treatment for patients with a worse prognosis.
Editorial Material
Pharmacology & Pharmacy
Jose de Leon, Carlos De Las Cuevas
Summary: ChatGPT3, a new artificial intelligence program, provided a mixture of true and false information regarding the metabolism of clozapine in African-Americans. It offered real and nonexistent references, defending opposite positions within a week on the clinically relevant issue.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
(2023)
Review
Medicine, General & Internal
Carlos de las Cuevas
Summary: Adherence to prescribed treatment is a major challenge in psychiatry, with non-adherence rates estimated to be as high as 50%. Two factors that have been suggested to influence medication adherence in psychiatric patients are perceived health control and psychological reactance.
PATIENT PREFERENCE AND ADHERENCE
(2023)
Review
Primary Health Care
Miguel Del-Pino, Emilio J. Sanz
Summary: Proton pump inhibitors (PPIs) have become the mainstream treatment for acid-related pathologies, but a significant proportion of people are overusing PPIs without approved indications. A narrative review on PPI deprescription strategies found that the clarity and simplicity of the de-escalation protocols and the training of physicians responsible for deprescribing were key factors for success.
PRIMARY HEALTH CARE RESEARCH AND DEVELOPMENT
(2023)