Structure-Function Analysis of the Human Ferroportin Iron Exporter (SLC40A1): Effect of Hemochromatosis Type 4 Disease Mutations and Identification of Critical Residues

Relation between sequence and structure in membrane proteins

(2013) Mireia Olivella et al.   BIOINFORMATICS

Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT

(2012) Sandra L. Ross et al.   Cell Metabolism

Hepcidin-Induced Endocytosis of Ferroportin Is Dependent on Ferroportin Ubiquitination

(2012) Bo Qiao et al.   Cell Metabolism

Hepcidin and iron regulation, 10 years later

(2011) T. Ganz   BLOOD

Identification of Mutations in SLC40A1 That Affect Ferroportin Function and Phenotype of Human Ferroportin Iron Overload

(2011) Roman Mayr et al.   GASTROENTEROLOGY

Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload

(2011) Gloria C. Preza et al.   JOURNAL OF CLINICAL INVESTIGATION

A Study of the Evolution of Inverted-Topology Repeats from LeuT-Fold Transporters Using AlignMe

(2010) Kamil Khafizov et al.   BIOCHEMISTRY

Human mutation D157G in ferroportin leads to hepcidin-independent binding of Jak2 and ferroportin down-regulation

(2010) I. De Domenico et al.   BLOOD

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Ferroportin disease: A systematic meta-analysis of clinical and molecular findings

(2010) Roman Mayr et al.   JOURNAL OF HEPATOLOGY

Functional analysis and theoretical modeling of ferroportin reveals clustering of mutations according to phenotype

(2009) Daniel F. Wallace et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The molecular basis of hepcidin-resistant hereditary hemochromatosis

(2009) A. Fernandes et al.   BLOOD

A novel missense mutation inSLC40A1results in resistance to hepcidin and confirms the existence of two ferroportin-associated iron overload diseases

(2009) Emilie Létocart et al.   BRITISH JOURNAL OF HAEMATOLOGY

Molecular models of the open and closed states of the whole human CFTR protein

(2009) Jean-Paul Mornon et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Investigation of the Biophysical and Cell Biological Properties of Ferroportin, a Multipass Integral Membrane Protein Iron Exporter

(2009) Adrian E. Rice et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2

(2009) I. De Domenico et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ins and Outs of Major Facilitator Superfamily Antiporters

(2008) Christopher J. Law et al.   Annual Review of Microbiology

Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network

(2008) Martina U. Muckenthaler et al.   Annual Review of Nutrition

RETRACTED: The Hepcidin-Binding Site on Ferroportin Is Evolutionarily Conserved

(2008) Ivana De Domenico et al.   Cell Metabolism

Atomic model of human cystic fibrosis transmembrane conductance regulator: Membrane-spanning domains and coupling interfaces

(2008) J.-P. Mornon et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Clinical, pathological, and molecular correlates in ferroportin disease: A study of two novel mutations

(2008) Domenico Girelli et al.   JOURNAL OF HEPATOLOGY

The major amino acid transporter superfamily has a similar core structure as Na+-galactose and Na+-leucine transporters

(2008) Juke S. Lolkema et al.   MOLECULAR MEMBRANE BIOLOGY