Mutations in the planar cell polarity genesCELSR1andSCRIBare associated with the severe neural tube defect craniorachischisis

Mutations in Prickle Orthologs Cause Seizures in Flies, Mice, and Humans

(2011) Hirotaka Tao et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular and Cellular Mechanisms Underlying Neural Tube Defects in the Loop-tail Mutant Mouse

(2010) Michel Gravel et al.   BIOCHEMISTRY

Loss of Membrane Targeting of Vangl Proteins Causes Neural Tube Defects

(2010) Alexandra Iliescu et al.   BIOCHEMISTRY

An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure

(2010) Muriel J. Harris et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

(2010) Anju Paudyal et al.   BMC DEVELOPMENTAL BIOLOGY

VANGL2Mutations in Human Cranial Neural-Tube Defects

(2010) Yun-Ping Lei et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetics of human neural tube defects

(2009) N. D.E. Greene et al.   HUMAN MOLECULAR GENETICS

Novel mutations inVANGL1in neural tube defects

(2009) Zoha Kibar et al.   HUMAN MUTATION

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

(2009) Janna Merte et al.   NATURE CELL BIOLOGY

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity

(2009) H. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The planar polarity pathway

(2008) David Strutt   CURRENT BIOLOGY

Cthrc1 Selectively Activates the Planar Cell Polarity Pathway of Wnt Signaling by Stabilizing the Wnt-Receptor Complex

(2008) Shinji Yamamoto et al.   DEVELOPMENTAL CELL