A shower of second hit events as the cause of multifocal renal cell carcinoma in tuberous sclerosis complex

Renal Cell Carcinoma in Tuberous Sclerosis Complex

(2014) Ping Yang et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma

(2014) Caleb F. Davis et al.   CANCER CELL

MET Is a Potential Target across All Papillary Renal Cell Carcinomas: Result from a Large Molecular Study of pRCC with CGH Array and Matching Gene Expression Array

(2014) L. Albiges et al.   CLINICAL CANCER RESEARCH

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

Exonic Mutations ofTSC2/TSC1Are Common but Not Seen in All Sporadic Pulmonary Lymphangioleiomyomatosis

(2013) Kameswara Rao Badri et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sun exposure causes somatic second-hit mutations and angiofibroma development in tuberous sclerosis complex

(2013) M. E. Tyburczy et al.   HUMAN MOLECULAR GENETICS

RASA1Mutations and Associated Phenotypes in 68 Families with Capillary Malformation-Arteriovenous Malformation

(2013) Nicole Revencu et al.   HUMAN MUTATION

Mutations in Hedgehog pathway genes in fetal rhabdomyomas

(2013) Simone Hettmer et al.   JOURNAL OF PATHOLOGY

Comprehensive molecular characterization of clear cell renal cell carcinoma

(2013)   NATURE

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

Perivascular Epithelioid Cell Tumors (PEComas) Harboring TFE3 Gene Rearrangements Lack the TSC2 Alterations Characteristic of Conventional PEComas

(2012) Izabela Malinowska et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

TACC3-TSC2 maintains nuclear envelope structure and controls cell division

(2010) Laia Gómez-Baldó et al.   CELL CYCLE

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Tuberous Sclerosis Complex Renal Disease

(2010) Bradley P. Dixon et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Tumor risks and genotype–phenotype–proteotype analysis in 358 patients with germline mutations inSDHBandSDHD

(2009) Christopher J. Ricketts et al.   HUMAN MUTATION

Germline SDHB Mutations and Familial Renal Cell Carcinoma

(2008) C. Ricketts et al.   JNCI-Journal of the National Cancer Institute

The TSC1-TSC2 Complex Is Required for Proper Activation of mTOR Complex 2

(2008) J. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY