Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia

Disruption of G-Protein γ5 Subtype Causes Embryonic Lethality in Mice

(2014) Anne M. Moon et al.   PLoS One

Protein phosphatase 1 catalytic isoforms: specificity toward interacting proteins

(2014) Luís Korrodi-Gregório et al.   Translational Research

Potential of Protein Phosphatase Inhibitor 1 As Biomarker of Pancreatic β-Cell Injury In Vitro and In Vivo

(2013) Lei Jiang et al.   DIABETES

Lipotoxicity disrupts incretin-regulated human β cell connectivity

(2013) David J. Hodson et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenomic plasticity enables human pancreatic α to β cell reprogramming

(2013) Nuria C. Bramswig et al.   JOURNAL OF CLINICAL INVESTIGATION

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets

(2012) Jalal Taneera et al.   Cell Metabolism

A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets

(2012) P. Marchetti et al.   DIABETOLOGIA

Regulation of Glucagon Secretion in Normal and Diabetic Human Islets by γ-Hydroxybutyrate and Glycine

(2012) Changhong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes

(2012) Sofia A. Andersson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Novel biomarkers for pre-diabetes identified by metabolomics

(2012) Rui Wang-Sattler et al.   Molecular Systems Biology

Multiple roles of phosphoinositide-specific phospholipase C isozymes

(2011) Pann-Ghill Suh et al.   BMB Reports

Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

(2011) R. J. Strawbridge et al.   DIABETES

Nuclear PLCs affect insulin secretion by targeting PPARγ in pancreatic β cells

(2011) Roberta Fiume et al.   FASEB JOURNAL

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

(2011) Jaspal S Kooner et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

(2011) Yoon Shin Cho et al.   NATURE GENETICS

Clusters of Conserved Beta Cell Marker Genes for Assessment of Beta Cell Phenotype

(2011) Geert A. Martens et al.   PLoS One

Cell biology of Ca2+-triggered exocytosis

(2010) Zhiping P Pang et al.   CURRENT OPINION IN CELL BIOLOGY

The PP1-R6 protein phosphatase holoenzyme is involved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase, a key regulator of insulin secretion, in MIN6 β cells

(2010) Luisa Garcia-Haro et al.   FASEB JOURNAL

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

(2010) Richa Saxena et al.   NATURE GENETICS

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts

(2008) A. Wojtusciszyn et al.   DIABETOLOGIA

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

(2008) Eleftheria Zeggini et al.   NATURE GENETICS

Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes

(2008) Valeriya Lyssenko et al.   NEW ENGLAND JOURNAL OF MEDICINE