Activation of AMP-activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis
出版年份 2014 全文链接
标题
Activation of AMP-activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis
作者
关键词
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出版物
HUMAN MOLECULAR GENETICS
Volume 24, Issue 3, Pages 787-801
出版商
Oxford University Press (OUP)
发表日期
2014-09-26
DOI
10.1093/hmg/ddu497
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mutant TDP-43 Deregulates AMPK Activation by PP2A in ALS Models
- (2014) Nirma D. Perera et al. PLoS One
- Traffic control at the nuclear pore
- (2014) Mohamed Kodiha et al. Nucleus
- Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis
- (2013) Emanuele D’Amico et al. FREE RADICAL BIOLOGY AND MEDICINE
- The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons
- (2013) Wenzhang Wang et al. HUMAN MOLECULAR GENETICS
- Effects of chronic caffeine intake in a mouse model of amyotrophic lateral sclerosis
- (2013) Rosa Luisa Potenza et al. JOURNAL OF NEUROSCIENCE RESEARCH
- The epidemiology of ALS: a conspiracy of genes, environment and time
- (2013) Ammar Al-Chalabi et al. Nature Reviews Neurology
- Molecular Signatures of Amyotrophic Lateral Sclerosis Disease Progression in Hind and Forelimb Muscles of an SOD1G93A Mouse Model
- (2012) Daniele Capitanio et al. ANTIOXIDANTS & REDOX SIGNALING
- Energy dysfunction in Huntington’s disease: insights from PGC-1α, AMPK, and CKB
- (2012) Tz-Chuen Ju et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Lost in Transgenesis
- (2012) Jennifer Davis et al. CIRCULATION RESEARCH
- Clinical Trials for Neuroprotection in ALS
- (2012) G. Siciliano et al. CNS & Neurological Disorders-Drug Targets
- Reduced Activity of AMP-Activated Protein Kinase Protects against Genetic Models of Motor Neuron Disease
- (2012) M. A. Lim et al. JOURNAL OF NEUROSCIENCE
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
- (2012) D. Grahame Hardie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Aberrant Localization of FUS and TDP43 Is Associated with Misfolding of SOD1 in Amyotrophic Lateral Sclerosis
- (2012) Edward Pokrishevsky et al. PLoS One
- Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS
- (2011) Victòria Ayala et al. ACTA NEUROPATHOLOGICA
- Familial versus sporadic amyotrophic lateral sclerosis--a false dichotomy?
- (2011) K. Talbot BRAIN
- Design and Synthesis of Novel Dual-Action Compounds Targeting the Adenosine A2A Receptor and Adenosine Transporter for Neuroprotection
- (2011) Jhih-Bin Chen et al. ChemMedChem
- Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking
- (2011) Todd J Cohen et al. EMBO JOURNAL
- Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington’s disease
- (2011) Tz-Chuen Ju et al. JOURNAL OF CELL BIOLOGY
- A New Drug Design Targeting the Adenosinergic System for Huntington's Disease
- (2011) Nai-Kuei Huang et al. PLoS One
- Hyperphosphorylation as a Defense Mechanism to Reduce TDP-43 Aggregation
- (2011) Huei-Ying Li et al. PLoS One
- Metformin Treatment Has No Beneficial Effect in a Dose-Response Survival Study in the SOD1G93A Mouse Model of ALS and Is Harmful in Female Mice
- (2011) Hannah M. Kaneb et al. PLoS One
- AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer’s disease and other tauopathies
- (2010) Valérie Vingtdeux et al. ACTA NEUROPATHOLOGICA
- Hydrogen peroxide stimulates nuclear import of the POU homeodomain protein Oct-1 and its repressive effect on the expression of Cdx-2
- (2010) Peixiang Wang et al. BMC CELL BIOLOGY
- Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration
- (2010) Agnes L. Nishimura et al. BRAIN
- The neurobiology of amyotrophic lateral sclerosis
- (2010) André Bento-Abreu et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Nuclear factor TDP-43 can affect selected microRNA levels
- (2010) Emanuele Buratti et al. FEBS Journal
- Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6)
- (2010) Chen-Li Chien et al. FEBS LETTERS
- TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
- (2010) C. Lagier-Tourenne et al. HUMAN MOLECULAR GENETICS
- Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis
- (2010) S. Byrne et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells
- (2010) Long Chen et al. LABORATORY INVESTIGATION
- Progressive motor weakness in transgenic mice expressing human TDP-43
- (2010) Nancy R. Stallings et al. NEUROBIOLOGY OF DISEASE
- Standards of Medical Care in Diabetes--2009
- (2009) DIABETES CARE
- Do patients with amyotrophic lateral sclerosis (ALS) have increased energy needs?
- (2009) Nachum Vaisman et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport
- (2009) Hidetaka Kosako et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Another gene for ALS: Mutations in sporadic cases and the rare variant hypothesis
- (2009) K. Talbot NEUROLOGY
- Mislocalization of TDP-43 in the G93A mutant SOD1 transgenic mouse model of ALS
- (2009) Xiaoyang Shan et al. NEUROSCIENCE LETTERS
- Dissecting the Signaling Events That Impact Classical Nuclear Import and Target Nuclear Transport Factors
- (2009) Mohamed Kodiha et al. PLoS One
- TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor
- (2008) I.-Fan Wang et al. JOURNAL OF NEUROCHEMISTRY
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