A comprehensive picture of the mutations associated with aromatic amino acid decarboxylase deficiency: from molecular mechanisms to therapy implications

Novel Inhibitors of Human DOPA Decarboxylase Extracted from Euonymus glabra Roxb.

(2014) Jie Ren et al.   ACS Chemical Biology

Mammalian dopa decarboxylase: Structure, catalytic activity and inhibition

(2014) Mariarita Bertoldi   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A next step in adeno-associated virus-mediated gene therapy for neurological diseases: regulation and targeting

(2013) Abdelwahed Chtarto et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Treatment of Congenital Neurotransmitter Deficiencies by Intracerebral Ventricular Injection of an Adeno-Associated Virus Serotype 9 Vector

(2013) Ni-Chung Lee et al.   HUMAN GENE THERAPY

S250F variant associated with aromatic amino acid decarboxylase deficiency: molecular defects and intracellular rescue by pyridoxine

(2013) Riccardo Montioli et al.   HUMAN MOLECULAR GENETICS

ConSurf: Using Evolutionary Data to Raise Testable Hypotheses about Protein Function

(2013) Gershon Celniker et al.   ISRAEL JOURNAL OF CHEMISTRY

Identification by Virtual Screening and In Vitro Testing of Human DOPA Decarboxylase Inhibitors

(2012) Frederick Daidone et al.   PLoS One

Molecular insights into the pathogenicity of variants associated with the aromatic amino acid decarboxylase deficiency

(2011) Riccardo Montioli et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases

(2011) G. Giardina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical and biochemical features of aromatic L-amino acid decarboxylase deficiency

(2010) L. Brun et al.   NEUROLOGY

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Multiple roles of the active site lysine of Dopa decarboxylase

(2009) Mariarita Bertoldi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Aromatic l-amino acid decarboxylase deficiency: clinical features, drug therapy and follow-up

(2009) C. Manegold et al.   JOURNAL OF INHERITED METABOLIC DISEASE