The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population

The admixture maximum likelihood test to test for association between rare variants and disease phenotypes

(2013) Jonathan P Tyrer et al.   BMC BIOINFORMATICS

Cancer statistics, 2013

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GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

(2013) Paul D P Pharoah et al.   NATURE GENETICS

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

(2013) Stig E Bojesen et al.   NATURE GENETICS

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

(2013) Jennifer Permuth-Wey et al.   Nature Communications

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

(2013) Hui Shen et al.   Nature Communications

Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer

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BRCA Mutation Frequency and Patterns of Treatment Response in BRCA Mutation–Positive Women With Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group

(2012) Kathryn Alsop et al.   JOURNAL OF CLINICAL ONCOLOGY

Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer

(2012) Jonathan Ledermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

SIFT web server: predicting effects of amino acid substitutions on proteins

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Analysis of 30 Putative BRCA1 Splicing Mutations in Hereditary Breast and Ovarian Cancer Families Identifies Exonic Splice Site Mutations That Escape In Silico Prediction

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Ovarian cancer linked to lynch syndrome typically presents as early-onset, non-serous epithelial tumors

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Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer

(2011) Shiyu Zhang et al.   GYNECOLOGIC ONCOLOGY

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Germline mutations in RAD51D confer susceptibility to ovarian cancer

(2011) Chey Loveday et al.   NATURE GENETICS

Mutations in BRIP1 confer high risk of ovarian cancer

(2011) Thorunn Rafnar et al.   NATURE GENETICS

Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing

(2011) T. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

The inherited genetics of ovarian and endometrial cancer

(2010) Simon A Gayther et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

(2010) Ellen L Goode et al.   NATURE GENETICS

Common variants at 19p13 are associated with susceptibility to ovarian cancer

(2010) Kelly L Bolton et al.   NATURE GENETICS

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

(2010) Alfons Meindl et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Consideration of hereditary nonpolyposis colorectal cancer in BRCA mutation-negative familial ovarian cancers

(2009) Stacey A. South et al.   CANCER

Meta-analysis of Risk Reduction Estimates Associated With Risk-Reducing Salpingo-oophorectomy in BRCA1 or BRCA2 Mutation Carriers

(2009) T. R. Rebbeck et al.   JNCI-Journal of the National Cancer Institute

The Contribution of BRCA1 and BRCA2 to Ovarian Cancer

(2009) Susan J. Ramus et al.   Molecular Oncology

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2

(2009) Honglin Song et al.   NATURE GENETICS

A review of the clinical relevance of mismatch-repair deficiency in ovarian cancer

(2008) Tuya Pal et al.   CANCER

Clinical Classification ofBRCA1andBRCA2DNA Sequence Variants: The Value of Cytokeratin Profiles and Evolutionary Analysis—A Report From the kConFab Investigators

(2008) Amanda B. Spurdle et al.   JOURNAL OF CLINICAL ONCOLOGY

BRCA1 and BRCA2 Missense Variants of High and Low Clinical Significance Influence Lymphoblastoid Cell Line Post-Irradiation Gene Expression

(2008) Nic Waddell et al.   PLoS Genetics